Hi-Risk/Recurrent/Advanced PCa Video Chat, Nov 28, 2023
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Pfizer, Janssen, Myriad Genetics, Myovant, Telix & Blue Earth Diagnostics.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Editor’s Pick: Advocating for what you want may not be advocating for what’s best for you. (bn)
Topics Discussed
PSA in the 60s, but Gleason 3+4 — time for a PSMA scan; SUV maxes of FDG PET and PSMA PET are unrelated and can’t be compared; don’t underestimate the chills and aches when starting zoledronic acid; Keytruda surpasses his expectations — a Christmas miracle? — but another man fails to respond; surprisingly good response after switching from daro to abi; docs agree to drop ADT — but advocating for what you want may not be advocating for what’s best for you; ADT is an easier ride when you’re knowledgeable and prepared; reminder: no cold turkey with prednisone; could monotherapy be a safer choice than ditching hard-to-tolerate ADT?; doc balks at genetic testing that could uncover therapy options
Chat Log
Richard Wassersug (Vancouver) · 6:09 PM
Myovant is now Sumitomo Pharma
AnCan – rick · 6:14 PM
Gleason Grade, right group????
Julian – Houston · 6:14 PM
I did read that Myovant got bought out!
Peter Kafka – Maui · 6:14 PM
He probably should be in the Low and Intermediate group.
Steven Friedman · 6:31 PM
stevenfriedman55@yahoo.com
AnCan – rick · 6:36 PM
peterk@ancan.org
Peter Kafka – Maui · 6:37 PM
peterk@ancan.org
Peter Kafka – Maui · 6:44 PM
Sounds similar to Len’s experience recently.
Len Sierra · 6:44 PM
Almost identical to me.
Unknown · 6:44 PM
My wife Ellen had the same response she like you and Len
J. Ward · 6:59 PM
I made it an hour, gents, and wanted everyone to know about the Reclast side effects. I’m going to take Dr. John’s advice and hop off the call to get rest. Good night!
Len Sierra · 7:15 PM
From RADICALS-HD trial: After a median follow-up of 9 years, the study investigators found that 24 months of ADT were superior to 6 months (HR 0.77, 95% CI [0.61, 0.97]; 72% vs 78% at 10 years) with respect to the primary endpoint of metastasis-free survival (MFS).
Unknown · 7:20 PM
Why not try mono therapy first with Dara?
Larry Fish · 7:26 PM
please spell this drug-suppliment
AnCan – rick · 7:26 PM
fenbendazole
Jim Marshall, Melbourne, FL on Vac · 7:26 PM
I managed my ADT + Abi for 5 years and it did not slow me down. Being diagnosed at 73 and now 79 has slowed me down more. Aerobic Exercise has been the key even when my body said it was exhausted, will power got me on the bike which promoted recovery. jim
AnCan – rick · 7:48 PM
Elizabeth Heath Karmanos
AnCan – rick · 7:48 PM
https://www.karmanos.org/karmanos/karmanos-physician-directory/heath-elisabeth-8225
Frank Fabish Columbus OH · 8:00 PM
See you guys. good session.
Steve Roux, MI · 8:07 PM
Guys, really need some dinner; see you next meeting. Great session and thanks to all of you!
Len Sierra · 8:07 PM
BXCL701 showed good results when used with Keytruda in both enzalutamide resistatnt mCRPC and with small cell neuroendocrine cancer.
Len Sierra · 8:09 PM
Chromogranin A (CGA) and neuron-specific enolase (NSE) levels are biomarkers for NEPC. Also, they are synaptophysin positive
AnCan takes a holistic approach to your physical and mental health. AnCan also recognizes that a healthy mouth contributes to a stress free life… and all too often your condition, or the meds you take for it, can disrupt dental health. Some of our groups speak frequently about dry mouth (xerostomia), loss of taste (ageusia) and ONJ … osteonecrosis of the jaw.
When, Dr. Bob Gurmankin DMD, a recently retired dentist living with advanced prostate cancer, noticed the frequency with which these dental topics came up in his group, he suggested a two-step support program – 1) a handout on our website, and 2) a dental health webinar in 2024… watch out for this int he New Year.
One handout alone was not going serve all needs so Dr. Bob graciously prepared THREE to kick start our effort to help you maintain a healthy mouth.
Please download whatever is appropriate and spread the word to others who you think may benefit. Dr. Bob Gurmankin can be reached at dr.bob@ancan.org ; if you have questions he has kindly agreed to assist… THANK YOU DR. BOB!!!
Please participate in our Groups where you’ll find more support… onward & upwards.
Hi-Risk/Recurrent/Advanced PCa Video Chat, Nov 20, 2023
HAPPY THANKSGIVING TO ALL OUR VIEWERS… may it be peaceful and full of gratitude.
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Pfizer, Janssen, Myriad Genetics, Myovant, Telix & Blue Earth Diagnostics.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Editor’s Pick: Persevere to the very end to hear us question docs who recommend Pluvicto knowing some mets won’t respond (rd)
Topics Discussed
Different MRI presentations can confuse; balance and falling; do dormant prostate cells express PSMA?; Pluvicto offers no quick result – Ac225 next??; don’t rush the prednisone taper; does your assigned doc have the right qualifications?; urinary issues lead to kidney failure – and a neck brace!; Orgovyx causes fewer hot flashes for some men; with mCRPC, don’t anguish over 0.1-0.3 PSA fluctuations; do historic doubling patterns hold when PCa recurs?; PCa recurs only IN the radiated gland – what next after 6 mo. HT?; ultra sensitive test redundant post-RT; does Pluvicto make sense for man with hybrid PCa?
Chat Log
Michael Wyn, Denversent · 6:15 PM
Thanks everyone. Good bye
Phil Dipaolasent · 6:19 PM
Hi, I would like a few minutes during the session today, if possible! Thanks, Phil Dipaola
sent · 6:21 PM
Phil – you have to be here in the first 10 minutes to be sure of time. PLEASE REFER TO OUR REMINDER. That’s the protocol with so many attendees.. If we have time at the end, we’ll certainly get to you.
sent · 6:22 PM
Were you tested for neuropathy?
Bill Franklinsent · 6:31 PM
Joel, if at all possible, don’t hesitate to ask for a physical therapy referral from your PCM. All the stuff Larry talked about would be worked on.
Bill Franklinsent · 6:37 PM
What age is considered elderly now? This is a serious question. Sometimes all doctors think about is the number on the age line. But many of us are in great shape.
TonyFigsent · 6:39 PM
I thought the Surf sound in Florida got louder in the winter. Maybe it is elderly shuffling their feet.
AnCan – ricksent · 6:52 PM
Google …… Alpha emitter vs Beta emitter PSMA radionuclide therapeutics
I will. turn 75 tomorrow, and I do not consider myself elderly!
My wife was a geriatric nurse. She had no time for doctors who blamed problems on an individual’s age.
AnCan – ricksent · 7:10 PM
Happy B-day to Alan Babcock!!!
JEFFERSONsent · 7:11 PM
thank you so much
Julian – Houstonsent · 7:14 PM
Happy B-day Alan!!!
Jimmy Greenfieldsent · 7:20 PM
Biological age , not the number. In my parent’s time 70 was elderly. People stopped moving. I know otherwise ‘healthy”50 year olds who are truly old, physically and/or behaviorally. Unfit, set in their ways etc. Then you have birthday boy Alan Babcock- 75 years young if ever I saw it.
sent · 7:21 PM
Hi I have a question about PSA test sensitivity. For the first time in about 6 months my level went below the ‘undetectable’ level as my local Kaiser defines it, <.06. Very grateful for that. Going forward, I’m wondering if I should be pushing Kaiser for a test with greater sensitivity? When people talk about their PSA testing I usually hear specificity below .06, but I’m not sure if there would be value for me in that ‘extra’ sensitivity. I am 3.5 years past initial radiation treatments not taking any medications at this point.
Alan Babcocksent · 7:22 PM
Thanks Jimmy
Jim Marshall, Jupiter, FL on Vacsent · 7:26 PM
You say not under treatment but have you been not being treatec for 3.5 yrs or on a treatment holiday. I’d press for PSA tests every 4 months. I am Kaiser too. but on treatment holiday gettng PSA test every month.
sent · 7:34 PM
Thank you Jim Marshall for the question; after radiation I did 2 years of Zytiga/prednisone, and haven’t yet had the need to restart.
Jim Marshall, Jupiter, FL on Vacsent · 7:36 PM
uugst PSA test ever 1-2 months because you are on holiday. In fact I get all the blood tests I got when under treatment. Kaiser has no problem with in in the DC area.
Jim Marshall, Jupiter, FL on Vacsent · 7:38 PM
although if the thought is you are in remission, then 3 months for a year and then either every 4 or 6 months going forward not needing all the other tests. Jim M
sent · 7:41 PM
Thank you Jim M!
Alan Msent · 7:46 PM
Matt, I have had the ultrasensitive PSA test done by Labcorp for 10 years. I prefer to see small changes and get an early warning of pending increases or decreased in PSA. I recommend it as long as it won’t give you anxiety.
Julian – Houstonsent · 7:47 PM
I am also doing the ultrasensitive PSA test every 3 months!
Alan Msent · 7:52 PM
Need to sign off guys. Good night.
Jim Marshall, Jupiter, FL on Vacsent · 8:03 PM
Kaiser has always given me PSA tests with 2 decimal places from the start 6.25 years ago. It has been less than 0.01 ever since I was on ABI + Lupron and into 15 months holiday.
Hi-Risk/Recurrent/Advanced PCa Video Chat, Nov 14, 2023
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Pfizer, Janssen, Myriad Genetics, Myovant, Telix & Blue Earth Diagnostics.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Editor’s pick: Full of urine and free of care (bn).
Topics Discussed
Remedies for full-bladder anxiety before radiation: Gemtesa, the Lunderg clamp, the Wiesner clamp, and the perfect glass of water; men who know less about their cancer than they should; does starting Provenge mean dropping abi?; what is Provenge?; docs OK ADT holiday after 7 months — we have our doubts; controversial off-label fenbendazole; painfully swollen leg 5 months after chemo — lymphedema or something else?; happy camper with rebounded testosterone and PSA low 9 months after radiation; struggling with rectal pain from a massive prostate tumor — a case for palliative care; he’s impatient for testosterone recovery; a doc predicts end of the road for Lupron as monotherapy becomes standard of care.
Chat Log
AnCan – rick · 6:10 PM
King Charles birthday too!
AnCan – rick · 6:17 PM
Alan B …. bet you wish you had known about that!!
AnCan – rick · 6:18 PM
Gemtesa – virbegron
AnCan – rick · 6:29 PM
Lundberg clamp; via Amazon
· 6:36 PM
Wiesner clamp also Amazon
AnCan – rick · 6:38 PM
Here’s teh study Vic referenced https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10320463/
AnCan – rick · 6:41 PM
Provenge / Sipileucel-T
todd rieke · 7:01 PM
Fenbendazole
AnCan – rick · 7:13 PM
Please run the use of any complementary or alternative medicine with your HCP!!
todd rieke · 7:13 PM
fenbenlab.com
J. Ward · 7:20 PM
Thanks. Wishing you success with Fenben and also with your consults at MDA and Guancale. I see Dr. Corn at MDA.
Jim Marshall, Melbourne, FL · 7:42 PM
I was on ADT for 5 years and it took 9 months for the testosterone to begin.
Julian – Houston · 7:47 PM
I got off all my medications 1 year ago and testosterone is at 125 last month.
Jim Marshall, Melbourne, FL · 7:49 PM
After 15 months the testosterone has trended down from 144 for the last 3 months. Interesting.
Julian – Houston · 7:50 PM
About the same, testosterone went up to 155 and came back down to 125.
Hi-Risk/Recurrent/Advanced PCa Video Chat, Nov 6, 2023
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Pfizer, Janssen, Myriad Genetics, Myovant, Telix & Blue Earth Diagnostics.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Editor’s pick: Several Gents face new lesions, and a couple of GU med oncs overlook the obvious! (rd)
Topics Discussed
Oligometastatic treatment strategies; could this be a recurrence?; single new bone lesion; PSMA shows metastatic lymph node; can prednisone suppress testosterone?; dehydration/low potassium causes brief blackout; full bladder strategies during RT; can you do Provenge while on androgen blockers; GU med onc overlooks PSMA scan; Next Generation Sequencing needed post Pluvicto; AUS coating could be the problem; chemo only works 25% of time
Chat Log
Peter Kafka – Mauisent · 6:33 PM
For some guys it is a question of whether the mets are causing pain or discomfort in deciiding to radiate
AnCan takes a holistic approach to your physical and mental health. AnCan also recognizes that a healthy mouth contributes to a stress free life… and all too often your condition, or the meds you take for it, can disrupt dental health. Some of our groups speak frequently about dry mouth (xerostomia), loss of taste (ageusia) and ONJ … osteonecrosis of the jaw.