A retrospective analysis of 3,065 patients with high-risk localized or locally advanced prostate cancer treated with IMRT in the English National Health Service between 2010 and 2013 was performed. The analysis compared GI and genitourinary (GU) complications for Prostate Only-IMRT versus Prostate + Whole Pelvic Lymph Node-IMRT. Three-year cumulative incidence was 14% for both groups for GI toxicity, and 9% and 8% for GU toxicity, for Prostate+PLN and Prostate-Only RT, respectively. The authors conclude that “Including PLNs in radiation fields for high-risk or locally advanced prostate cancer is not associated with increased GI or GU toxicity at 3 years.”
For the full abstract published in the Journal of Clinical Oncology, click here: https://doi.org/10.1200/JCO.18.02237