AnCan thanks the following sponsors for making this recording possible: Novartis, Telix and Blue Earth Diagnostics.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Does the PROTEUS trial (RRP + doublet) set a good example?
Topics Discussed
Does surgery with doublet (PROTEUS trial) make sense for 72 yr old; Dana Farber visit raises questions about ‘diffuse’ cells and PSMA tracer agents; sensitive PSA test needed post surgery; VA approves daro but too early for Truqap; hormone resistance post triplet raises RLT vs chemo vs ???; Cu67 SAR-bisPSMA alternative to Pluvicto; switch to local GU PSMA for ease of treatment; small peritoneal lesions double in size to 4mm over 5 years – treat or not?; drug holiday success – PSA declines and T rises 🎉
Chat
Carl – Indiana sent: 6:12 PM
Tin Caps are welcome
Len Sierra sent: 6:40 PM
I’m at my son’s house in Maryland using his computer. Not sure what’s going on. I’ll just listen
Active Surveillance Prostate Cancer Video Chat, October 28th, 2026
AnCan is grateful to the following sponsors for making this recording possible: Novartis, Blue Earth Diagnostics, Telix, and Foundation Medicine.
Active Surveillance (AS) for low-risk prostate cancer involves unique challenges compared to other treatments. This online support group is designed for men and their caregivers who are currently on or considering AS. We hold four meetings monthly, recording only the second and fourth sessions. Our discussions cover a wide range of topics, including anxiety management, biopsy experiences, and the decision-making process around continuing or discontinuing AS. Newcomers are given priority to share their experiences, so we encourage you to join us.
You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/. Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/.
Hi-Risk/Recurrent/Advanced PrCa Video Chat, Oct. 27, 2026
AnCan WEBINAR Thu. Oct, 29 @ 8pm Eastern -” What’s new in radioligand therapy… and how to access it” w. Drs. Mike Hofman and Frankis Almaguel. Register https://short.do/jFCa8I
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix and Blue Earth Diagnostics.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Should minor presence of neuroendocrine cancer from lymph biopsy be a concern? And of course Dr. Paul on NCCN’s E2 approval
Topics Discussed
Inherited mutation makes RRP follow up protocol less clear; what comes after success with triplet but what comes next?; GG5 Newbie does 24 months doublet and wants to know likelihood of recurrence; Ki67 indicates slight presence of neuroendocrine cancer – implications; creatine helps with muscles and fatigue; leg lymphedema bothersome; is E2 available with salvage RT; how quickly does T return with E2; talking NCCN E2 approval with Dr. Paul; can E2 replace Prolia?; over-intensification may have caused heart issues; addressing hot flashes; maintaining exercise in the face of doublet HT; octogenarian does well post triplet and drug holiday; with 2+ bad boy mutations, who’s the best GU med onc to QB care?
Thank you for your help and input. I need to go, but look forward to connecting in the future.
Brian Haack – Eagle, ID sent: 4:28 PM
How long after drug holiday (9 months ADT doublet tx) should I wait until getting blood work? I’m on my 2nd recurrence btw. Don’t want to interrupt the great dialogue
Jim Marshall, Vet Sup Grp. Moderator sent: 4:32 PM
I get blood work every month now for 9+ years, the last 4+ years on Holiday. Kaiser permits it. Hopefully getting PSA test during the holiday to know when it starts to rise.
George Kander sent: 4:32 PM
thanks guys i have to go. see you next week
Len Sierra sent: 4:45 PM
Just a counter opinion: Clinical trials in patients with colorectal or prostate cancer found that creatine supplements generally failed to improve muscle mass, physical function, or quality of life during treatment.
Sam Kaufman (Oakland CA) sent: 4:47 PM
Sorry I cant stay until Im called. My questions can wait two weeks.
Jim Ekrut, Fort Worth TX sent: 5:03 PM
Thanks for another helpful and informational session!
Brian Haack – Eagle, ID sent: 5:05 PM
Gotta bounce… great discussion
TonyFig sent: 5:07 PM
Great meeting. See you next week
Frank D sent: 5:18 PM
Thanks for great meeting. Very helpful!
Bob Schwartz, USN, Venice, FL. sent: 5:19 PM
Another good mtg., have to go.
“Thomas” Matica sent: 5:21 PM
Great meeting. Dinner is on the table. Next time. Peace.
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix and Blue Earth Diagnostics.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: E2 doublet discussion – closely followed by integrating psilocybin into HT doublet!
Topics Discussed
Newbie diagnosed 4 years back with PSA @ 4000 & BRCA+ might consider a different doublet -or PARP; Newbie responds but has 4 consecutive negative PSMA scans – consider Axumin; could E2 doublet be an option?; PTEN just indicated; 2 negative Bx confirm our hunch Gent is Mx ; can experienced user integrate psilocybin into his HT to treat depression; monotherapy daro works exceptionally well – but must make decision on ‘Long Game’ trial; how long to stay on mono daro?; 1st Pluvicto rings PSA down a little – what to expect next?; Dr. Guancial uses fewer tests making Gent anxious – T/W her!
I want to ask Dr A if I can do the psilocybin therapy again while receiving radiation
Bob Schwartz, USN, Venice, FL. sent: 6:33 PM
Danny, we’re all here for you brother.
Gary Martin sent: 6:42 PM
RT can impact bone marrow–lowering blood counts and possibly increasing fatigue. This happened to me–lowering blood counts further to below-normal–on top of impact of triplet prior to RT.
Read that ice packs have been shown to limit the effects of Pluvicto on salivary glands–study in Europe. Don’t have a reference to study yet.
Hank Zajic Springfield VA sent: 7:10 PM
Good night all. Thank you for the discussion. out of battery here. Hank
Active Surveillance Prostate Cancer Video Chat, October 14th, 2026
AnCan is grateful to the following sponsors for making this recording possible: Novartis, Blue Earth Diagnostics, Telix, and Foundation Medicine.
Active Surveillance (AS) for low-risk prostate cancer involves unique challenges compared to other treatments. This online support group is designed for men and their caregivers who are currently on or considering AS. We hold four meetings monthly, recording only the second and fourth sessions. Our discussions cover a wide range of topics, including anxiety management, biopsy experiences, and the decision-making process around continuing or discontinuing AS. Newcomers are given priority to share their experiences, so we encourage you to join us.
You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/. Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/.
Chat Log:
Hugh Houston 8:12 PM
https://ancan.org/prostate-cancer-and-gu-pathology-2nd-opinions/ • Jonathan Epstein, MD, Advanced Uro Pathology T: 516-760-2037 (jepstein@imppllc.com) https://advanceduropathology.com • Ming Zhou, MD, PHD, Mount Sinai (NYC) Health T: 516-760-2037 Ming.zhou@mountsinai.org • Jesse McKenney, MD, Cleveland Clinic https://clevelandcliniclabs.com/healthcare-provider-resources/pathology/ • Johns Hopkins Pathology https://pathology.jhu.edu/patient-care/second-opinions
Phil Segal 8:13 PM
mskaeley@gmail.com
Phil Segal 8:15 PM
dmclachlan@gmail.com
Ed C in California 8:18 PM
My charge from Dr Jonathan Epstein was $900 without an insurance payment
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix and Blue Earth Diagnostics.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Do you get PSMA PET after doublet then how often?; and, how to say Guancial!
Topics Discussed
Younger Newbie graduates to our Group post RRP; treated after 20 yrs of AS.. but in the wrong group; finding the best trial for Frank; Bx cannot confirm PrCa; spot RT may be the ticket; all sable during IHT; RT to commence this month; what’s in Dr. Guancial’s name?; PSMA scans pos doublet are negative; when and how often to PSM scan; GU MO denies Pluvicto post triplet though scans light up; Gent decides to start TRT; brief discussion of HLD-0915
Chat
Bob Schwartz, USN, Venice, FL. sent: 3:17 PM
I can agree as to the hospital sling I received last time, for my other shoulder surgery. Which was why I was glad to hear your recommendation of a better one, prior to my upcoming surgery. Wish I didn’t need the surgery, but old age & past injuries, are catching up with me.
Steve L…. Hold tight and we’ll have the mugs available in our shop before long. You can order and take care of biz.
Alfredo in Wimberley, TX sent: 4:31 PM
Family calling – I must drop off now. Best wishes to all!
Steve Schuler (Seattle) sent: 4:31 PM
I wondered why I hadn’t heard anything… Answer: beurocrac
(can’t spell it though… :^(
Len Sierra sent: 4:36 PM
JAMA Oncol. 2019, 5, 856-863. In the first prospective trial of 68Ga-PSMA-11 PET/CT for BRPC, which included 635 patients, detection rates were 38% for PSA levels of < 1.0 ng/mL (n = 79), 84% for 1.0 to 2.0 (n=89), 86% for 2.0 to 5.0 (n=158), and 94% for >5.0. (BRPC = Bio-Recurrent PC)
Steve Schuler (Seattle) sent: 4:41 PM
a meta-observation is that most therapies that are initially only for end stage move earlier in treatment where their use there improves things. improves at least in the CSS sense, not necessarily in the OS sense
Len Sierrasent: 4:46 PM
New Terminology: • Androgen Pathway Modulator Sensitive: Tumors that continue to respond to or are controlled by androgen pathway suppression/blockade. • Androgen Pathway Modulator Resistant: Tumors that progress despite treatment targeting the androgen pathway
Steve – Seattle sent: 4:49 PM
My Calendar has the Ancan Seattle dinner scheduled for Sunday but I don’t have any details.
rick davis sent: 4:51 PM
Stand by as I said.
Steve Schuler (Seattle) sent: 4:53 PM
I’ve got to drop, but I will “stand by” to hear about Sunday. I will be at the conference Saturday, probably at Fred Hutch which I assume must be a video screen but in the FH building… That way I get a free sandwich I think :^)
RJ Smith (Seattle) sent: 4:54 PM
Same here–see you there Steve!
rick davis sent: 4:54 PM
: NCT06800313 HLD0915
George Kander
sent: 4:56 PM
Family calls – have to go. Thanks everyone and hopefully see you at dinner Friday in Portland – Chhers
