Hi-Risk/Recurrent/Advanced PrCa Video Chat, 5/4/26
Survey Opportunity
$200 for a 60min interview. Must be mHSPC or mCRPC; 40-75+/-; NOT have used Talzenna, Xtandi or Orgovyx. Reach out to Jason at 773 383 9090 jturner@flinceresearch.com. 15 needed. Indicate you are via AnCan and let us know if accepted (rd@ancan.org)
AnCan thanks the following sponsors for making this recording possible: Novartis, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Mutation issues prevail tonight… but also 1.4 PSA on mono daro raises questions.
Topics Discussed
Does PTEN change HT duration?; low/intermediate Gent sneaks in; gynecomastia prevention; is a 1.4 PSA on mono daro good or bad?; 2nd opinion for another PTEN Gent; BRCA Gent finds new lead GU MO; HIFU for recurrence within prostate; bad reaction to first chemo; PSA rises 4x in 3 months; younger Newbie follows triplet against TP53 and PTEN
Chat
AnCan – Rick sent: 4:53 PM
Flince survey…. NO Talzenna, Xtandi or Orgovyx JTurner@flinceresearch.com
40-75 +/- metastatic
AnCan–John A sent: 5:42 PM
germline (inherited) gene test
AnCan–John A sent: 5:44 PM
Dr Epstein: advanceduropathology.com (516)280-7930
Don Rogers sent: 6:06 PM
anastrozole 1 mg twice a week
Len Sierra sent: 6:24 PM
The only study I’m aware of was the EMBARK trial with 3 arms: ADT alone, Enzalutamide alone, and combo of enzalutamide and ADT. Read about that trial.
Richard B, Silver Spring, MD sent: 6:31 PM
I need to step away to take a phone call. I appreciate the efforts of the AnCan team for their efforts to this evening’s discussion.
AnCan–John A sent: 6:33 PM
cabazitaxel Jevtana
AnCan Bill sent: 6:34 PM
Frank is still on. Just not in front of his camera right now.
Bruce Schrimpf sent: 6:59 PM
Thanks guys! As always good!
Jim Marshall, Vet Support Grp. Moderator sent: 7:03 PM
Another Trial for PTEN for mCRPC is being run by the VA and GW Hospital called the Carpet Trial. Jim M
“Thomas” Matica sent: 7:03 PM
Good night, gents. Very good meeting and many thanks to our great moderators
$200 for a 60min interview. Must be mHSPC or mCRPC; 40-75+/-; NOT have used Talzenna, Xtandi or Orgovyx. Reach out to Jason at 773 383 9090 jturner@flinceresearch.com. 15 needed. Indicate you are via AnCan and let us know if accepted (rd@ancan.org)
AnCan thanks the following sponsors for making this recording possible: Novartis, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: PSA rockets to 186 and bone mets are found 5 months after prostatectomy; AND, self-advocacy pays off!
Topics Discussed
Recurrence (salvage) RT success but Newbie is anxious; BRCA germline Newbie in treatment at MSKCC; PSA skyrockets right after surgery and mets are found; treatment doing its work and GU med onc confirms path; great experience with AnCan Advisor Dan Georg who endorses treatment; 2nd opinion where academic conflict of interest is suspected; bad reaction to Zometa; chemo steroids create mega-munchies – GLP1 helps; if enz is not making issues, don’t switch; BRCA gets Gent to finally see a GU med onc; rash from coming off HT meds; self-advocating shortens time on HT doublet
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Don’t blame it on the prostate cancer… two Gents report tenderness but is it something else?
Topics Discussed
Newbie prescribed singlet HT when doublet was SoC – don’t switch w.3 months left but change docs; is cystoscopy the right procedure?; IHT after 3 years – but what bout shortness of breath; is tenderness from exercise or cancer?; is HT the right first step on BCR; insurance declines Axumin; starting AMG509 xaluritamig trial; stable on mono daro at 86; just finished 6th Pluvicto for foamy cell PrCa; don’t fret over tiny PSA moves; is chest tenderness down to HT or a previous cancer?; not eligible for Capitello trial – needs 2nd opinion on intensification
Chat
AnCan – Ric sent: 3:04 PM
GoTo Help 877 582 7011
Danny sent: 3:13 PM
Have to duck out for a couple of minutes.
David D Seattle sent: 3:14 PM
David joined by phone, I have an update
Len sent: 3:31 PM
Yes, my brother in arms, I was at the beach today. Water temp was 73. Re: your email – did you complete your chest RT?
Hello Steve! Yes, I’ll need to step up my sunblock to spf 50. UV index is high every day. How’s by you?
Adrian (Tony) Bruno sent: 3:51 PM
ask him what his hemoglobin level is
Steve Roux, Up North, Michigan sent: 4:00 PM
I got to run gang. So good to see you all. Great meeting as usual!
Joseph (Sean) Siry – Laguna Woods, CA. sent: 4:04 PM
Dinner is on the table, so I will have to go also– & I can report next time the good news.
AnCan – Rick sent: 4:06 PM
For everyone – Please tell us if you think you need to leave early…(should have added, “and you asked for time’:rd)
Bob Y — Los Angeles sent: 4:13 PM
I also need to leave early. Happy to see all of you.
Jim E., Ft. Worth T sent: 4:17 PM
While I haven’t had “Germline” testing, I had a complimentary gene testing through a group called Color, and they indicated no concerns for increased risk. I have logged in and opened my biopsy and PSMA PET results.
Bruce Schrimpf sent: 4:27 PM
I may have b e to leave there is a tornado warning for areas just to the South of my home. BDS
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: addressing insomnia… and AnCan helps men switch docs.
Topics Discussed
T3b Gent needs clarification on his Bx before starting treatment; how much HT before discussing intermittent; starting doublet; Nagar suggests IMRT is better for this Gent; switching HT drugs may address castrate resistance; Cialis for nocturia – maybe; potential cardio-onc in Portland, OR; Kishan’s ANDROMEDA trial attractive to men with slow recurrence; can prostate cancer cells be dormant?… follow up post-recording suggests YES.
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Toss up between ANDROMEDA trial and dormant cancer discussion
Topics Discussed
T3b Gent needs clarification on his Bx before starting treatment; how much HT before discussing intermittent; starting doublet; Nagar suggests IMRT is better for this Gent; switching HT drugs may address castrate resistance; Cialis for nocturia – maybe; potential cardio-onc in Portland, OR; Kishan’s ANDROMEDA trial attractive to men with slow recurrence; can prostate cancer cells be dormant?… follow up post-recording suggests YES.
Chat
AnCan – Rick sent: 4:58 PM
RJ – please call 877 582 7011 for HELP!!
Dial In 646 749 3129 #222 583 973
Jeff Marchi – San Francisco sent: 5:23 PM
Rajni Sethi is a Radiation Oncologist
Jim Marshall, Vet Support Grp. Moderato sent: 5:33 PM
Dr Jonathan Epstein. Advanced Uropathology of New York 700 Stewart Ave, Suite 101 Garden City, NY 11530 Hours: Monday-Friday 9:00AM – 6:00PM P: 516-760-2037 F: 516-200-3899 jepstein@imppllc.com
Jeff Marchi – San Francisco sent: 5:36 PM
orgovyx
Jeff Marchi – San Francisco sent: 5:38 PM
Ductal is very aggressive, is it really Ductal
Jeff Marchi – San Francisco sent: 5:39 PM
that would call for 2nd
Bob Schwartz, USN, Venice, FL. sent: 5:44 PM
Veterans, in Capt. Jim, We Trust!
Jim Marshall, Vet Support Grp. Moderator sent: 5:45 PM
Jim Marshall, USAF(RET), 703-338-7341. veterans@ancan.org
May be a GU cardiologist: Maros Ferencik OHSU Knight Cardiovascular Institute Cardiology Clinic, Beaverton, OR 1-503-494-1775
Jeff Marchi – San Francisco sent: 6:49 PM
Actinium major problem with dry mouth
Jeff Marchi – San Francisco sent: 6:50 PM
more according to studies
10-25%have severe dry mouth
Larry (Alaska-Estradiol as ADT monotherapy) sent: 6:52 PM
Alpha particles simply have a shorter penetration than beta particles, so cellular damage is more limited to the locations the ligand binds the radioactive material. The problem with both is that the radioactive material is placed everywhere there is uptake of the ligand.
Joseph (Sean) Siry – Laguna Woods, CA. sent: 6:52 PM
So the actinium treatment does not rely on knowing the precise location of the metastasis?
Larry (Alaska-Estradiol as ADT monotherapy) sent: 6:53 PM
Joseph/Sean, both treatments (using ligands) bind to the same cells. The ligand (sort of) “knows” where to bind.
Joseph (Sean) Siry – Laguna Woods, CA. sent: 6:59 PM
my Testosterone is in the 180 + level, would systemic treatment rule me out due to ADT is just started?
