Hi-Risk/Recurrent/Advanced PrCa Video Chat, Oct. 27, 2026
AnCan WEBINAR Thu. Oct, 29 @ 8pm Eastern -” What’s new in radioligand therapy… and how to access it” w. Drs. Mike Hofman and Frankis Almaguel. Register https://short.do/jFCa8I
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix and Blue Earth Diagnostics.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Should minor presence of neuroendocrine cancer from lymph biopsy be a concern? And of course Dr. Paul on NCCN’s E2 approval
Topics Discussed
Inherited mutation makes RRP follow up protocol less clear; what comes after success with triplet but what comes next?; GG5 Newbie does 24 months doublet and wants to know likelihood of recurrence; Ki67 indicates slight presence of neuroendocrine cancer – implications; creatine helps with muscles and fatigue; leg lymphedema bothersome; is E2 available with salvage RT; how quickly does T return with E2; talking NCCN E2 approval with Dr. Paul; can E2 replace Prolia?; over-intensification may have caused heart issues; addressing hot flashes; maintaining exercise in the face of doublet HT; octogenarian does well post triplet and drug holiday; with 2+ bad boy mutations, who’s the best GU med onc to QB care?
Thank you for your help and input. I need to go, but look forward to connecting in the future.
Brian Haack – Eagle, ID sent: 4:28 PM
How long after drug holiday (9 months ADT doublet tx) should I wait until getting blood work? I’m on my 2nd recurrence btw. Don’t want to interrupt the great dialogue
Jim Marshall, Vet Sup Grp. Moderator sent: 4:32 PM
I get blood work every month now for 9+ years, the last 4+ years on Holiday. Kaiser permits it. Hopefully getting PSA test during the holiday to know when it starts to rise.
George Kander sent: 4:32 PM
thanks guys i have to go. see you next week
Len Sierra sent: 4:45 PM
Just a counter opinion: Clinical trials in patients with colorectal or prostate cancer found that creatine supplements generally failed to improve muscle mass, physical function, or quality of life during treatment.
Sam Kaufman (Oakland CA) sent: 4:47 PM
Sorry I cant stay until Im called. My questions can wait two weeks.
Jim Ekrut, Fort Worth TX sent: 5:03 PM
Thanks for another helpful and informational session!
Brian Haack – Eagle, ID sent: 5:05 PM
Gotta bounce… great discussion
TonyFig sent: 5:07 PM
Great meeting. See you next week
Frank D sent: 5:18 PM
Thanks for great meeting. Very helpful!
Bob Schwartz, USN, Venice, FL. sent: 5:19 PM
Another good mtg., have to go.
“Thomas” Matica sent: 5:21 PM
Great meeting. Dinner is on the table. Next time. Peace.
Stay in shape with FIT Together in your own living room!
Mark and Kathy Baldridge are avid birders, and as a result, frequent visitors to “Deep Southern Arizona” from their home in University Place, Washington. You may have seen them in an AnCan Group – we’ve been supporting the Baldridges since 2021.
Recently Mark mentioned an at home exercise program in a group, so we encouraged him to tell us more so all AnCan’rs living with cancer could participate… with or without their care partner.
This October 17th, AnCan will participate in the OHSU-Fred Hutch Prostate Cancer Summit. Dr. Kerri Winters is also speaking, and Dr. E (Eleni Efstathiou), the new Chief of Genitourinary Cancer at OHSU, has already set up a time for us to meet. We’ll be writing about the Summit closer to the date. (rick davis)
Back in high school, I did multiple pushups before I went to bed. Fast-forward 50 years and I was unable to do a single pushup. Over the years, I’d fooled myself into thinking I was in ‘decent shape’ because I took long walks several times a week. The truth was that after being diagnosed with osteoporosis, 24 months of Hormone Therapy and a lack of upper body exercise, my overall strength had significantly declined.
Fortunately, I discovered an online exercise program FIT Together for cancer survivors and their partners. FIT Together is a 501(c)(3) nonprofit organization founded in 2014 under the leadership of Dr. Kerri Winters-Stone and Jessica Sitemba. Dr. Winters-Stone has a PhD in Human Performance and has been conducting research in exercise oncology for 20 years. She has run over 15 clinical trials funded by NIH and cancer non-profits. I have participated in two of Dr. Winters-Stone’s clinical trials run through Oregon Health Sciences University – OHSU.
I’ve attended FIT Together classes for a year and can attest that the instructors are excellent. They demonstrate each exercise and then give tips to ensure each participant correctly performs the exercise. The instructors individualize and tailor movements and exercises to accommodate each person’s needs—no matter what the person’s fitness level. For instance, pushups can be performed in many different ways (e.g. against a wall/desk/chair or on hands and knees/feet).
The classes are held twice per week at various times virtually. I love the convenience of performing these exercises at home and look forward to each class. All you need for the classes are dumbbells, a resistance band, stretch strap and an exercise mat. The cost for this equipment is quite reasonable—less than $75.
There are several classes to choose from: strength training, strength/cardio and an exercise class for couples. Classes are very reasonably priced— around $5 per session for a 12 week/24 session class… even less if two of you join together.
I participate in the strength training class and physically feel much better about myself. It’s been really encouraging to see that I’ve slowly gained upper body strength. While I still can’t do a pushup on my hands and toes, I can perform 12 pushups on my hands and knees—I’m on my way to performing a full pushup.
I highly recommend these classes and hope to see some of you in a class—you won’t be disappointed!
AnCan thanks the following sponsors for making this recording possible: Novartis, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Ask for an EKG if you’re on hormone therapy – Dr. Alfredo says it’s cheap!
Topics Discussed
Newbie switches ADT after EKG; wearing a Holter patch; white diet during radiation; AnCan’r signs up for ANDROMEDA; 8 lesions but all above the pelvis call for new QB; no treatment for 12 mo. more, so why worry about what’s available; T returns and PSA says low; Axumin may find what PSMA does not; dental issue; insist on regular DEXA and PSMA scans during treatment; PTEN and TP53 somatic emerge – will it change treatment?; MSKCC doc drops the ball; steady as she goes on mono daro at 89; E2 needs name for its newsletter
Chat
Billy Ingersoll sent: 3:23 PM
QTC 482 from 420/437
Alfredo in Sacramento sent: 3:26 PM
Medicare covers 72% of the EKG (Electrocardiogram) cost. Beneficiaries should budget approximately $4 in out-of-pocket costs. EKG (Electrocardiogram) costs vary 37% across states: from $12 in Arkansas to $17 in Alaska. At $15 nationally, EKG (Electrocardiogram) is a low-cost procedure. For most Medicare beneficiaries, the coinsurance will be under $50. The patient cost of $4 is within the annual Part B deductible ($257), making this relatively affordable for Medicare beneficiaries.
Jim Marshall, Vet Sup Grp. Moderator sent: 3:46 PM
There is GOTO Help. 877-582-7011 if want to ask why. Jim
Avery Becton sent: 3:46 PM
ok. thx
Avery Becton sent: 3:51 PM
Finally I can hear the group on my PC
Bob Schwartz, USN, Venice, FL. sent: 3:58 PM
Great mtg., see everyone next mtg., have to go.
Alfredo in Sacramento sent: 3:58 PM
Gotta go now, best wishes to all.
AnCan–John A sent: 4:11 PM
next-generation sequencing or genomic or somatic test .on the biopsy sample
Jim Marshall, Vet Sup Grp. Moderator sent: 4:12 PM
Genitourinary Medical Oncologist
David D Seattle sent: 4:51 PM
I have to run to another meeting. Have a good evening all.
Alan Moskowitz sent: 4:56 PM
bye all
J. Ward sent: 4:59 PM
What was the date of Len’s write-up again, please?
AnCan thanks the following sponsors for making this recording possible: Novartis, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: No Newbies – but repeating topics: incontinence; heart issues; and, intermittent vs continuous hormone therapy
Topics Discussed
Foamy gland AnCan’r does well with Pluvicto but has urinary issues; incontinence issues defer salvage RT; PCPEP program solid but time consuming; AnCan’r getting AUS this week; neck fan outperforms venlafaxine for hot sweats; low T and still hot sweats; Gent on abi cuts back his prednisone and has muscle pains; are cardio issue down to oncology treatments/; after 24 mo doublet, is it time for a change?; Dr. E’s available to sort his protocol – our AnCan’r just has to call; ending HT takes time to reverse the side effects
SDHA sig for paragangliomas (noncancerous) and GI stromal tumors, and pheos. We need not be concerned it looks like
Len Sierra sent: 6:18 PM
From the AnCan website, my comments from 2024: Tumor responses improved following a steroid switch from prednisone to dexamethasone in castration-resistant prostate cancer patients progressing on abiraterone: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264443/ Conclusions: Durable PSA responses occur in up to 40% of patients following a ‘steroid switch’ for PSA progression on abiraterone and prednisone
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Toss up between ANDROMEDA trial and dormant cancer discussion
Topics Discussed
T3b Gent needs clarification on his Bx before starting treatment; how much HT before discussing intermittent; starting doublet; Nagar suggests IMRT is better for this Gent; switching HT drugs may address castrate resistance; Cialis for nocturia – maybe; potential cardio-onc in Portland, OR; Kishan’s ANDROMEDA trial attractive to men with slow recurrence; can prostate cancer cells be dormant?… follow up post-recording suggests YES.
Chat
AnCan – Rick sent: 4:58 PM
RJ – please call 877 582 7011 for HELP!!
Dial In 646 749 3129 #222 583 973
Jeff Marchi – San Francisco sent: 5:23 PM
Rajni Sethi is a Radiation Oncologist
Jim Marshall, Vet Support Grp. Moderato sent: 5:33 PM
Dr Jonathan Epstein. Advanced Uropathology of New York 700 Stewart Ave, Suite 101 Garden City, NY 11530 Hours: Monday-Friday 9:00AM – 6:00PM P: 516-760-2037 F: 516-200-3899 jepstein@imppllc.com
Jeff Marchi – San Francisco sent: 5:36 PM
orgovyx
Jeff Marchi – San Francisco sent: 5:38 PM
Ductal is very aggressive, is it really Ductal
Jeff Marchi – San Francisco sent: 5:39 PM
that would call for 2nd
Bob Schwartz, USN, Venice, FL. sent: 5:44 PM
Veterans, in Capt. Jim, We Trust!
Jim Marshall, Vet Support Grp. Moderator sent: 5:45 PM
Jim Marshall, USAF(RET), 703-338-7341. veterans@ancan.org
May be a GU cardiologist: Maros Ferencik OHSU Knight Cardiovascular Institute Cardiology Clinic, Beaverton, OR 1-503-494-1775
Jeff Marchi – San Francisco sent: 6:49 PM
Actinium major problem with dry mouth
Jeff Marchi – San Francisco sent: 6:50 PM
more according to studies
10-25%have severe dry mouth
Larry (Alaska-Estradiol as ADT monotherapy) sent: 6:52 PM
Alpha particles simply have a shorter penetration than beta particles, so cellular damage is more limited to the locations the ligand binds the radioactive material. The problem with both is that the radioactive material is placed everywhere there is uptake of the ligand.
Joseph (Sean) Siry – Laguna Woods, CA. sent: 6:52 PM
So the actinium treatment does not rely on knowing the precise location of the metastasis?
Larry (Alaska-Estradiol as ADT monotherapy) sent: 6:53 PM
Joseph/Sean, both treatments (using ligands) bind to the same cells. The ligand (sort of) “knows” where to bind.
Joseph (Sean) Siry – Laguna Woods, CA. sent: 6:59 PM
my Testosterone is in the 180 + level, would systemic treatment rule me out due to ADT is just started?
AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: AnCan’r considering AMG509 STEAP T-Cell engager; does IDC-P make you high risk?
Topics Discussed
Newbie needs GU MO and doublet; ADT and heart issues; BRCA2 germline Gent progresses after RP; no evidence for doublet; long-timer needs to switch treatment; moving from Pluvicto to xaluritamig/ AMG509/ STEAP trial; supplemental E2 discussed by peer – insurance issues, gui9dance on E2 blood levels; IDC-P man on RT asks how much HT; with BCR, doubling time may be more significant guide to BCR than actual PSA level
Chat
Jim Marshall, Vet Support Grp. Moderator sent: 6:33 PM
Joining from the air. No mic available. I just blogged the Estradiol conversation.
AnCan – Rick sent: 7:36 PM
Kishan would say 6 months per his recent meta study
Show Tran the Kishan paper
Jeff Marchi – San Francisco sent: 7:37 PM
has he had genetic testing? it can frequently be associated with genetic issues
AnCan – Rick sent: 7:37 PM
12 months if you’re more aggressive.
Is Spratt the final author
Steve Schuler (Seattle) sent: 7:40 PM
I just wrapped it up a month ago. Now I’m on nothing, no ADT either. I was on Lupron for 2 years, abiraterone also for 2 years, but started a year after the Lupron started (there’s a story there, but later), and then on Estradiol for most of the time I was on abiraterone. But now on nothing. For most of the E2, it was .05mg (50 microgram) patches 2 per week. So a box of 8 lasts you 4 weeks. With GoodRX, those were $13/box
A word about the dose level of the patches: that’s the estimated dose delivery of a patch per day. The amount of E2 in the patch itself is higher, something like 600 microgram is what I remember, but then it releases slowly at an ESTIMATED rate of 50. But that release rate is highly dependent on the amount of fat under the skin, etc. So your milage will vary
Mark N sent: 7:44 PM
Thanks for the feed back!
dan-s alexandria sent: 7:48 PM
thanks Jimmy
Pierre D., Olean, NY sent: 7:52 PM
Thank you all for your input.
Jeffrey G sent: 7:53 PM
We were in the 90s today. Ugh, warmest AZ winter i’ve ever been in. Still, gotta be grateful for warm weather and for a psa of 0.02…Adios
Mark and Kathy Baldridge are avid birders, and as a result, frequent visitors to “Deep Southern Arizona” from their home in University Place, Washington. You may have seen them in an AnCan Group – we’ve been supporting the Baldridges since 2021.