Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick:  Unrelated Newbies from either Coast have almost identical issues.

Our two Newbies are ‘twins’ – both denovo Mx on the cusp between high and low volume mets, and both with less experienced GU med oncs; 4x chemo down doing well with a full head of hair!; finding an exercise program; contacting NCI; Orgovyx trumps a 6-mo. depot shot; early radiation cystitis; finding Dr. E; with heart history, Orgovyx or Lupron?; discussing NCI trial & adaptive therapy

Chat
  • AnCan – Rick sent: 5:55 PM

    Technical assistance 877 582 7011

  • AnCan – Rick sent: 5:56 PM

    Playing the Long Game https://www.youtube.com/watch?v=v4jzyAeOtNI

  • Steve Roux, North Michigan sent: 6:25 PM

    orgovyx

  • AnCan–John A sent: 6:25 PM

    aka relugolix

  • Steve Roux, North Michigan sent: 6:26 PM

  • Eric James; Tyler TX  sent: 6:28 PM

    So they were unable to find any prostate cancer within the prostate biopsies? That is strange.

  • AnCan–John A sent: 6:29 PM

    right, Eric

  • Steve Roux, North Michigan sent: 6:29 PM

    But the MRI came after the biopsy I think

  • Steve Roux, North Michigan sent: 6:29 PM

    ?

  • AnCan–John A sent: 6:30 PM

    MRI 2 pelvic lesions PIRADS 4 and 5. July 2025

  • AnCan–John A sent: 6:30 PM

    biopsies April and August

  • Steve Roux, North Michigan sent: 6:32 PM

    So the 1st biopsy was a “blind” biopsy

  • Len sent: 6:32 PM

    Yes, Steve.

  • AnCan – Rick sent: 6:34 PM

    Dr. David Wise, GU Med Onc NYU Langone https://nyulangone.org/doctors/1336438258/david-r-wise 

    Dana Rathkopf GU MO http://www.mskcc.org/cancer-care/doctor/dana-rathkopf

  • Steve Schuler (Go Seahawks!) sent: 6:46 PM

    And also the bone strengtheners question

  • Steve Roux, North Michigan sent: 6:56 PM

    Someone from Seattle is called a Seattleite

  • Steve Schuler (Go Seahawks!) sent: 6:58 PM

    Someone from Michigan is a Michigander. I’m both.

  • Jim Marshall, Veteran, Alexandria, VA sent: 6:59 PM

    Heck, Indianians are HOOSIERS

  • AnCan–John A sent: 7:04 PM

    prostate anc bladder specialist

  • Jim Marshall, Veteran, Alexandria, VA sent: 7:05 PM

    Indeed I heart issues and Aberaterone is off the table for the future when I go back on treatment. Jim

  • Jeff Marchi – San Francisco sent: 7:06 PM

    no kidding Jim , abi caused me a lot of heart issues

  • AnCan – Rick sent: 7:07 PM

  • Steve Schuler (Go Seahawks!) sent: 7:14 PM

    Have they done a DEXA (for your bone)?

  • Steve Roux, North Michigan sent: 7:18 PM

    Great Meeting again gang! I’m out – time to walk the dog.

  • michael perillo sent: 7:21 PM

    Hi all, need to leave the meeting. Obviously have quite a bit of work to do re possible change to orggovyx, possible use of radiation, chemo or other triplet approach, possible somatic testing as well as second opinion. Will follw up on future meetings. Thanks Michael

  • AnCan–John A sent: 7:21 PM

    Ok Michael, welcome

  • Eric James; Tyler TX sent: 7:25 PM

    The weight you use is relative to your strength. Weight is usually selected based on how many reps you are to do.

  • Steve Schuler (Go Seahawks!) sent: 7:31 PM

    Did you have doubling time data before going on the ADT?

    The reason I ask is that there will be a lag after going off ADT before the DT data will be reliable

  • Eric James; Tyler TX sent: 7:33 PM

    The NCI doc presentation has some overlap with Adaptive Therapy

  • Steve Schuler (Go Seahawks!) sent: 7:38 PM

    Orgovyx will restore your T faster once you get off it

  • RJ Smith (Seattle) sent: 7:48 PM

    ChatGPT, etc.) is not a GU Med Onc. Not even a urologist or MD of any kind.

  • Steve Schuler (Go Seahawks!) sent: 7:56 PM

    gotta drop, love to hear more discussion of the NCI YT video at some point. If that happens after I drop, I’ll view the recording of this session later

  • Richard B, Silver Spring, MD sent: 8:02 PM

    I need to step away due to an early start tomorrow morning. Nothing new to report but more assessments this week. So possible report next week. ‘Appreciate all the conversations. Good night.

  • dan-s alexandria sent: 8:03 PM

    gotta go, gents…. good conversations.

  • Bruce Schrimpf sent: 8:11 PM

    As always it was very informative. Thanks for being “there” for those of us struggling through!

  • AnCan – Rick sent: 8:12 PM

John G sent: 8:12 PM

https://www.moffitt.org/newsroom/news-releases/moffitt-researchers-identify-key-factors-impacting-adaptive-therapy/ 

  • Frank Ciambra to Everyone 08:26 PM good night
  • Bruce Schrimpf to Everyone 08:27 PM I have heard the line about dying with and not from prostate cancer many times! BDS
  • Bob Alvord to Everyone 08:28 PM Thank you all for the illuminating discussions. Bye till next time.
Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

“Playing the Long Game” – Does your Recurrent/Advanced Prostate Cancer Need Treating? NCI Seminar

“Playing the Long Game” – Does your Recurrent/Advanced Prostate Cancer Need Treating?

National Cancer Institute Seminar with Dr. Ravi Madan and Dr. Melissa Abel,  Jan 30, 2026

READ THROUGH – you won’t regret it!! (rd)

A recent article in the Journal of Clinical Oncology with a very dry title caught our eye – National Cancer Institute’s Working Group on Biochemically Recurrent Prostate Cancer: Clinical Trial Design Considerations

AnCan has long been perplexed by the prostate cancer category “non-metastatic Castrate Resistant” or even “non-metastatic Hormone Sensitive”. If PSA is rising after primary treatment but prior to hormone treatment, something’s going on, however, ‘micro-metastatic’. It’s like being just a little bit pregnant!!

This paper considers a new category, PSMA Positive Biochemically RecurrentPSMA+ BCR. We circulated the paper to our Brains Trust and reached out to Dr. Ravi Madan at the National Cancer Institute (NCI) with a couple of questions. Dr Madan offered to meet with us along with his colleague, Dr. Melissa Abel. What resulted was this REMARKABLE video that could present many of our recurrent and advanced AnCan (& non-AnCan) participants with one of the most mind-blowing videos many have seen in a long time,

DO YOU REALLY NEED TREATMENT??

As the venerable and highly respected Dr. Paul Schellhammer said in the meeting, “it’s like listening 15 years ago to the folks who began to promote active surveillance ( in first line treatment)”     Dr. Madan and Dr. Abel have collected solid data from around 150 patients that suggests men with slow PSA doubling times can “play the long game” as Dr. Ravi calls it, and defer active treatment when their disease recurs.

PLEASE watch this astonishing presentation, listen to some excellent observations and questions, and consider how it relates to your own situation. And spread the word to others. Dr. Madan’s and Dr. Abel’s NCI clinical trial can be found at https://www.clinicaltrials.gov/study/NCT05588128. Don’t immediately assume you’re not eligible before speaking with them… but you’ll have to watch the video to get their contact information.

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/27/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/27/26

AnCan is closing out its Annual Fundraising Campaign. If you haven’t donated yet, consider the priceless value we bring . Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

HEADS-UP: another marathon session!!

Editor’s Pick: Disruptor attends solely to advocate for Dr. Kwon… and makes AnCan’s case with his own inappropriate overtreatment.

Topics Discussed 

Potentially de novo metastatic Gent prefers faith to treatment; … and this de novo Mx man has fared well on doublet and radiotherapy RT; he’s more interested in chastising AnCan over Kwon than his own overtreatment; radiation proctitis discussion; kidneys backwashed from possible radiation damage; Clomid slow to restore T… give it time Dr. Jack; considering immunotherapy well before its time; raises the question – does TMB differ between tissue and blood samples?; v. low testosterone may not be related to previous PrCa treatment; new GU MO needed in Central Florida; PSMA is negative but started on Lupron; why shlepp to MDA – what’s wrong with Chicago?; back- end Newbie needs a GU med onc rather than uro; Kwon proselytizer won’t give up; Canadian placed on doublet per AnCan navigation is feeling good and grateful

Chat
  • Jon McPhee Toronto sent: 4:13 PM

    Toronto is in Canada

  • Dan – Schenectady, NY sent: 4:41 PM

    Thank you Bob

  • AnCan – Rick sent: 4:55 PM

    Telephone # for tech assistance: 877 582 7011

  • Frank Ciambra sent: 5:25 PM

    got to go ,see guys net week everyone have great weekend

  • Bruce Schrimpf sent: 5:38 PM

    Got to go. Best to all of you! BDS

  • Lee Baylin sent: 5:45 PM

    Good night.

  • AnCan – Rick sent: 5:45 PM

    my DEXA showed -2.0 in spine and forearm last week. Doc just wants me to supplement with calcium and D.

    oh… and resistance exercise!!

  • Steve Roux, North Michigan sent: 5:46 PM

    I’m doing the same +K2

    I resist exercise daily.😆

  • Peter M sent: 5:57 PM

    good night gents!

  • Steve Roux, North Michigan sent: 5:58 PM

    Great Meeting gang. I gotta run . Good night all.

  • Jim Marshall, Veteran, Alexandria, VA sent: 6:05 PM

    Hey, 3 1/2 years on a Treatment Holiday and all is good. Jim

  • Julian – Houston sent: 6:15 PM

    Thanks All – I will contact Dr E!

  • Thomas Matica sent: 6:15 PM

    Good night. Thanks to everyone. Peace. Thomas.

  • Ron S Regina SK Canada sent: 6:21 PM

    Thanks all. Gotta go.

  • Richard B, Silver Spring, MD sent: 6:27 PM

    Goodnight gentlemen, I appreciate the feedback tonight. Very helpful

  • Jon McPhee Toronto sent: 6:29 PM

    Nite all.

  • Bob Schwartz U.S.N. Venice, FL. sent: 6:32 PM

    Good mtg., see you next week.

  • Jim Marshall, Veteran, Alexandria, VA sent: 6:58 PM

    Genitourinary Medical Oncologist

  • AnCan – Rick sent: 6:59 PM

    Dr Russell Szmulewitz

  • AnCan – Rick sent: 7:27 PM

    MIchael Ong

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/19/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/19/26

 

AnCan is closing out its Annual Fundraising Campaign. If you haven’t donated yet, consider the priceless value we bring . Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: After 15 years, Prostate cancer recurs for one Gent; and the 2nd time, 13 years later, for another.

Topics Discussed 

Newbie needs to switch to a GU MO; PrCa metastasizes after 15 yrs; singlet to doublet during RT; Pluvicto failing after 10x sessions – STEAP1 xaluritamig (AMG509 ) next but heads up!; early signs of 2nd recurrence; Eligard vs Firmagon (agonist vs antagonist LHRH); first GU med onc appointment coming up; managing hot flashes; Oxybutynin again; doc can’t get approval right so switches drug; PSMA shows Nodes may not need RT; abiraterone dosing;

Chat
  • Rick Davis sent: 6:10 PM

    PLEASE – no mention of the Championship Game tonight. Some peeps are recording it.

  • Rick Davis sent: 6:41 PM

  • Julian – Houston sent: 7:02 PM

    Need to leave – pass my bedtime. Catch you all next week!

  • Bob Schwartz U.S.N. Venice, FL. sent: 7:03 PM

    Another GOOD Mtg., have to go, see everyone next week.

  • Rick Davis sent: 7:26 PM

    Xaluritamig (AMG 509) is a novel bispecific T-cell engager (TCE) immunotherapy

  • Bob Y — Los Angeles sent: 7:27 PM

    Appreciate everyone. I, too, have to go. See you next week.

  • Len sent: 7:30 PM

    STEAP1 (Six-Transmembrane Epithelial Antigen of the Prostate 1) is detected in prostate cancer (PCa) primarily through tissue analysis (immunohistochemistry), showing overexpression in malignant cells, and via liquid biopsies (extracellular vesicles in plasma), using methods like nanoscale flow cytometry,

  • AnCan–John A sent: 7:31 PM

    thanks Len

  • Frank Ciambra sent: 7:32 PM

    thank you

  • Rick Davis sent: 7:32 PM

    Doubling time very unreliable at such low levels, Neil

  • dan-s sent: 7:40 PM

    I also have to scoot… thanks all.

  • Barbara and Joe sent: 7:54 PM

    are you saying lupron?

  • Jim Marshall, Veteran, Alexandria, VA sent: 7:55 PM

    Lupron & Eligard are the exact same drug. Jim

  • Rick Davis sent: 7:56 PM

    Are you asking about the Depot shots?

  • Rick Davis sent: 7:57 PM

    Oxybutynin…. good for hot flashes if you are on abi

  • Steve L sent: 7:57 PM

    Must leave at 7, Best to all.

  • Alain sent: 7:58 PM

    See you next time guys!

  • Barbara and Joe sent: 7:58 PM

    I was asking about a two tier therapy

  • Steve Lsent: 7:59 PM

    no , thank you.

  • Alfredo in Houston, TX sent: 8:00 PM

    I must disconnect shortly. Thanks to everyone; I learn something new from every session.

  • Rick Davis sent: 8:01 PM

    ADT + ARSI = doublet. ADT can be one of several drugs.

  • Thomas Matica sent: 8:02 PM

    Signing out. Thanks to everyone. Peace.

  • Len sent: 8:02 PM

    Dan – Trade name for oxybutynin is Ditropan.

  • Barry Blomquist sent: 8:06 PM

    Thanks guys!

  • Richard B, Silver Spring, MD sent: 8:09 PM

    As much as I would like to remain I need to bow out for the evening. I can save my question until next session. Always appreciate the information on these meeting. Good night!

  • Alfredo in Houston, TX sent: 8:09 PM

    good night

  • Dan – Schenectady, NY sent: 8:16 PM

    Thank you – have to go

  • Robert sent: 8:18 PM

     Thanks for another good meeting.

  • Ed L sent: 8:22 PM

    Thanks for the input. Good night.

  • Jon McPhee Toronto sent: 8:26 PM

    Bed time. Good meeting again. Night.

  • Bruce Schrimpf sent: 8:36 PM

    Thanks for the great meeting!

  • Barbara and Joe sent: 8:37 PM

    Thanks all

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

AnCan is closing out its Annual Fundraising Campaign. If you haven’t donated yet, consider the priceless value we bring . Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Denovo metastatic BRCA2 Newbie stumps us all!

Topics Discussed

High volume denovo Mx Gent with BRCA germline can’t fiing a treatment that controls his T or his PSA; starting IMRT along with constipation; 2nd docetaxel easier with less fatigue than the first; liver returning to normal after 6x docetaxel; so back to full daro dose; T returns within 3 months of stopping 12 mo of orgovyx; BCBS turns down Prolia for -2.7 osteoprosis – did doc ask for wrong denosumab; ‘ciiling cap’ discussion; opting for new Plan Ds (drugs); Inherited Mutations discussed;

Chat
  • Alfredo in Houston, TX sent: 4:24 PM

  • Larry (Alaska) sent: 4:50 PM

    should we test for LH and FSH levels?

  • Alfredo in Houston, TX sent: 4:51 PM

    Dr. Jack, would an LH level be helpful in this case?

  •  Jeff Marchi – San Francisco sent: 4:52 PM

    small cell= neuroendocrine (not exactly: rd)

  • AnCan–John A sent: 4:55 PM

    advanceduropathology.com 5162807930 Dr Epstein prostate pathology expert

  • Alfredo in Houston, TX sent: 5:00 PM

    the relatively long half-life of injectable testosterone undecanoate means its effects can last for weeks, but probably not months

  • Jeff Marchi – San Francisco sent: 5:08 PM

    has anyone had VMAT radiation?

  • Gary Martin sent: 5:09 PM

    I had that prostate inflammation first and second round docetaxel. my oncologist did not know cause. Suggested UTI, which have the same symptom I had in round 1 and 2. I figured it was chemo working on prostate.

  • Julian – Houston sent: 5:13 PM

    Jeff, I have had VMAT radiation.

  • Jeff Marchi – San Francisco sent: 5:13 PM

    how well did it work? any side effects?

  • Jack sent: 5:14 PM

    Enzalutamide blocks androgen binding which disrupts the negative feedback loop that normally supresses testosterone this leads to compensatory increases in LH and subsequent increases in testosterone

  • Julian – Houston sent: 5:14 PM

    It worked quite well – I have been in remission for over 5 years. I am now having some radiation effects but not severe

  • AnCan – rick sent: 5:18 PM

  • Bruce Schrimpf sent: 5:20 PM

    I have not met or heard of him.

  • Gary Martin sent: 5:32 PM

    I had insurance denial of Prolia (bone strengthening)- anyone encounter denial of Prolia?

  • Julian – Houston sent: 5:34 PM

    Aetna no longer approves Prolia.

  • Larry (Alaska) sent: 5:36 PM

    Bone loss is largely drivenby estradiol deficiency (just as it is in post-menopausal women). Testosterone deprivation also lowers a man’snatural estradiol. A low-dose estradiol suppement can avoid the need for bune-building agents. Agents which are expensive and bring their own set of adverese side effects.

  • Larry (Alaska) sent: 5:43 PM

    Calcium + Magnesium:

    AI Says: Why Separation Helps Competition for Absorption: High levels of calcium can block magnesium absorption in the intestines, and vice-versa. Optimizing Intake: Spacing them out (2-4 hours apart is a common suggestion) minimizes this competition, allowing your body to absorb each mineral more effectively. When It’s Okay to Take Them Together Multivitamins: If they are in smaller, balanced amounts within a multivitamin, the interaction is usually not an issue. With Food: Taking them with food can also help with absorption and reduce digestive upset.

  • RJ Smith (Seattle) sent: 5:47 PM

    Cold Cap system is https://paxmanscalpcooling.com/

  • Julian – Houston sent: 5:52 PM

    Volumetric-modulated Arc Therapy (VMAT)

  • Alfredo in Houston, TX sent: 5:55 PM

    Well, here is a longish article, but it does seem to describe the difference between IMRT and VMAT, https://en.wikipedia.org/wiki/Radiation_therapy

  • Julian – Houston sent: 5:57 PM

  • Alfredo in Houston, TX sent: 5:58 PM

    I have to leave now, sending everyone good wishes for the new year. Good night! and thank you!

  • Alan Swope sent: 5:59 PM

    Thanks all. I have to leave. Good information.

  • Don Rogers sent: 5:59 PM

    look at Scriptco.com for generic drugs. Huge saving even with the $140 yearly fee.

  • Bruce Schrimpf sent: 6:01 PM

    Thanks for the good discussion!

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 2/2/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/5/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/5/26

HAPPY NEW YEAR to all AnCan’s YouTube viewers.    AnCan is closing out its Annual Fundraising Campaign. If you haven’t donated yet, consider the priceless value we bring . Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

 

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

HEADSUP – another long session!

Editor’s Pick: Like London buses, topics come in clusters this week – post-surgery recurrence, and monotherapy daro

Topics Discussed

Recurrence 3+ months post-surgery is confusing given medical reports; sitting on hands post 2017 RRP has dire cinsequences; more rapid recurrence requires PSMA scan for younger Gent; low T post treatment raises question whether to force it castrate; oxybutinin manages hot sweats… ARSI makes no difference; Gent considers going from doublet to mono; recently diagnosed denovo Mx man learns he’s 5+4; should he keep one Pluvicto session in reserve?; get a DEXA scan before starting bone stregthener; can a layman read their PSMA scan?; is he ready for mono daro?; should a FAP (Fibroblast Activation Protein Inhibitor) scan be considered?; PSMA needed as PSA rises post IHT; connections between prostate and thyroid cancer; Gent resumes doublet but doesn’t watch PSA – more concerned with duration?!?

Chat
  •  Jim Stewart Reno, NV sent: 7:24 PM

    Family commitment have to sign off…Happy New Year everyone

  • Jim Marshall, Veteran, Alexandria, VA sent: 7:36 PM

    My solution for HOT FLASHES at night has been is even if the room is 55, I have a 12″ fan blowing directly on my face. This is done year round.

  • Paul Schomer sent: 7:50 PM

    I am not, no, Jim

  • RJ Smith (Seattle) sent: 7:50 PM

    NTD–will update next week on how Chemo#3 goes (docetaxel infusion tomorrow, fingers crossed).

  • Thomas Matica sent: 8:07 PM

    Leaving the meeting. Thanks to everyone. Happy New Year.

  • Jim Marshall, Veteran, Alexandria, VA sent: 8:11 PM

    Eric – When you are fatigued, go out and exericse despite the body telling you NOT!!!!

  • S. Datta sent: 8:14 PM

    FAPI (Fibroblast Activation Protein Inhibitor)

  • Larry Schuller – Alaska sent: 8:18 PM

    It is not crazy to want your testosterone back. Intermittent ADT can do that and it is showing promise as a tactic. Bipolar ADT (BAT) is a little crazier, but has some promise also. If you want to go wild, check out Dr Robert Gatenby’s work at Moffit in Florida. Intersesting stuff there.

  • John G. sent: 8:19 PM

  • AnCan – rick sent: 8:20 PM

  • Jeffrey Green sent: 8:23 PM

    Jay Mills Chatanooga- Though I didn’t follow the whole conversation, I heard you say something to the effect of, “I may have mets all over the place, in addition to what shows on PSMA.”

  • Barry Blomquist sent: 8:28 PM

    Have to jump – thanks everyone. Happy New Year

  • Eric Curtis sent: 8:30 PM

    Thanks all – gotta go

  • Jeffrey Green sent: 8:31 PM

    Got to start winding down here. Thanks for all you guys. See you next time.

  • Len sent: 8:34 PM

    Source is AI: Bidirectional Risk: Men diagnosed with thyroid cancer have a roughly 28% to 30% higher risk of later being diagnosed with prostate cancer compared to the general population. Conversely, men with prostate cancer are more likely to be diagnosed with thyroid cancer.

  • Robert sent: 8:35 PM

    Thanks Len. I read the same thing.

  • dan-s sent: 8:49 PM

    Thanks all… another good session. Have to sign off for the evening. Happy New Year…

  • Jay T in MN sent: 8:50 PM

    My hospital was charging the insurance company about $20,000.

  • gary peters sent: 8:50 PM

    I did not know this about thyroid C and PC. Thank you.

  • Jon McPhee Toronto sent: 8:50 PM

    Do a PSA test once a month. Cheap. PSMA/PET is expensive and harder to get.

  • Jay T in MN sent: 8:51 PM

    I “only” had to pay $1000 for my portion of PET PMSA