Low/Intermediate PCa Video Chat, March 9, 2026

Low/Intermediate PCa Video Chat, March 9, 2026

by | Mar 11, 2026 | Cancer Caregivers, Cancer Resources, Low/Intermediate Prostate Cancer, Recorded Groups

Low/Intermediate PCa Video Chat, March 9, 2026

Low/Intermediate PCa Video Chat, March 9, 2026

AnCan is grateful to the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics, and Foundation Medicine.

WELCOME all to our newly recorded Low/Intermediate Prostate Cancer Group. To receive notice when new recordings are posted, either follow us on this YouTube Channel or sign up to our Blog via https://ancan.org/contact-us/ – check New Blog box.

Join our other free and drop in groups:
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime!

Editor’s Pick: The value of connecting with other AnCan peers to compare doctor recommendations and treatment experiences. (bj)

Topics Discussed
Management of Benign Prostatic Hyperplasia (BPH) and prostate size; comparison of radiation modalities such as stereotactic body radiation therapy (SBRT), intensity-modulated radiation therapy (IMRT), magnetic resonance-guided linear accelerator (MRI-Linac) and brachytherapy; comparison of androgen deprivation therapy (ADT) medications: Orgovyx vs Lupron; importance of genomic tests like Decipher, Prolaris, Artera AI, and the PROMISE study (germline testing); discussion on surgical options and surgeon recommendations;  advantages of transperineal over transrectal biopsies; benefits of MRI-fusion biopsies for targeted sampling; veterans get medical treatments through Veterans Affairs (VA) can use Community Care to get access to specialized medical care outside the VA; lymph node involvement seen in a PSMA scan changes disease categorization and requires more advanced drugs; importance of consulting a cardio-oncologist when adding ADT treatments for prostate cancer while recovering from heart surgery; discussion between how long a low/intermediate prostate cancer patient can wait between a diagnosis requiring an active treatment (such as prostatectomy, radiation, hormone therapy) and starting active treatment;  the value of connecting with other AnCan peers at similar stages of their journey to compare doctor recommendations and treatment experiences.

Chat

Stuart sent a chat · 8:01 PM
Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881

Stuart sent a chat · 8:02 PM
Dr. Jonathan Epstein – https://advanceduropathology.com/  Tel:516-760-2037    jepstein@imppllc.com

Bob in Georgia sent a chat · 8:34 PM
can you put those doctor name and contacts in the chat?

AnCan – Rick sent a chat · 8:40 PM
Eggener https://www.uclahealth.org/providers/scott-eggener

AnCan – Rick sent a chat · 8:41 PM
Kishan  UCLA  https://www.uclahealth.org/providers/amar-kishan

AnCan – Rick sent a chat · 8:41 PM
Eggener is UCLA

David in Portland, OR sent a chat · 8:43 PM
Paper on delaying treatment (Mack Roach is co-author): “Delayed Definitive Management of Localized Prostate Cancer: What Do We Know?” Prostate Cancer and Prostate Diseases, Aug. 2024, https://www.nature.com/articles/s41391-024-00876-2

Larry S – ADT by estradiol sent a chat · 8:46 PM
Get baselines for lyour 1) Bone density 2) Hormone levels (especially testosterone) 3) your muscle strength and lean to fat ratio.  These can change with ADT and (in my opinion) you want keep track.

AnCan – Rick sent a chat · 8:48 PM
Brisbane – surgeon  UCLA https://www.uclahealth.org/providers/wayne-brisbane

AnCan – Rick sent a chat · 8:49 PM
Peter Carroll – surgeon UCSF  https://urology.ucsf.edu/people/peter-r-carroll

AnCan – Rick sent a chat · 8:50 PM
Matt Cooperberg  surgeon UCSF  https://urology.ucsf.edu/people/cooperberg

AnCan – Rick sent a chat · 8:50 PM
Mack Roach rad onc UCSF  https://www.ucsfhealth.org/mack.roach

Larry S – ADT by estradiol sent a chat · 8:53 PM
Talk to your doctors about the side effects of ADT, especially if you will be using it for very long.

AnCan – Rick sent a chat · 9:11 PM
Bob…  MRLinac at MSKCC Dr. Nagar

Mark WV sent a chat · 9:27 PM
good night

AnCan – Boykin sent a chat · 9:28 PM
good night

Steve in Malaysia sent a chat · 9:32 PM
Was wondering if I can ask a question or 2.

AnCan – Boykin sent a chat · 9:32 PM
Steve I have you on the list…you’re last

Steve in Malaysia sent a chat · 9:32 PM
Thanks 🙂

Steve K sent a chat · 10:01 PM
Good night. Thanks everyone.

AnCan – Boykin sent a chat · 10:01 PM
Good night Steve K

Larry S – ADT by estradiol sent a chat · 10:03 PM
Cannot stay.  Good night.

AnCan – Boykin sent a chat · 10:03 PM
Good night Larry S

AnCan – Rick sent a chat · 10:06 PM
SBRT vs HDR https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2845485?utm_source=email&utm_campaign=content-shareicons&utm_content=article_engagement&utm_medium=social&utm_term=022826

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 3/10/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 3/10/26

by | Mar 11, 2026 | High Risk/Recurrent/Advanced, High Risk/Recurrent/Advanced Prostate Cancer, mCRPC, mHSPC, Prostate Cancer, Recorded Groups, Uncategorized

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 3/10/26

 

Listen to our recent Estradiol discussion https://ancan.org/learn-from-ancans-emperors-of-estradiol-021626/

Recent article on AnCan in Rarity life. https://ancan.org/rarity-life-magazine-featuring-rick-davis/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Two men recur from low levels, one younger, while a much younger man is denovo metastatic.

Topics Discussed

Fit 87 yr old seeks more treatment ideas; younger man recurs post-LDR brachy for 3+4; – cud be a NCI candidate; 3+3 comes back after 5 yrs as 4+5; PSA stays high but stable after 9 months of doublet – change docs!; Clomid causing heart issues; Long Game candidate gives update; Axumin goes AWOL; another very young Newbie with multiple 5+5 cores needs a GU MO; Gent switches care at MSKCC

Chat

  • AnCan – Ricksent: 3:14 PM

    877 582 7011 – GoTo Technical Help Room # 222 583 973

  • Bob Schwartz, USN, Venice, FL. sent: 3:30 PM

    Dr. Elizabeth Guancial, 1970 Golf St. Sarasota, FL. 34236, (941)957-1000. https://flcancer.com/en/physician/elizabeth-guancial-md/

  • AnCan – Rick sent: 3:31 PM

    Cabazitaxel/Jevtana should be discussed

  • Steve L sent: 3:34 PM

    Thanks Jeff

  • Jeff Marchi – San Francisco sent: 3:51 PM

    orgovyx

  • Answercare sent: 3:51 PM

    Mach Roach at UCSF. Is he good?

  • Jeff Marchi – San Francisco sent: 3:52 PM

    roach is radiation oncologist

  • AnCan – Rick sent: 3:52 PM

    Rahul Aggarwal http://cancer.ucsf.edu/people/profiles/aggarwal_rahul.7339

  • Jeff Marchi – San Francisco sent: 3:52 PM

    he needs a GU oncologist

  • Bill Franklin sent: 3:55 PM

    https://ancan.org/?s=playing+the+long+game

  • AnCan – Rick sent: 3:56 PM

    Terry Friedlander https://www.ucsfhealth.org/terence.friedlander

  • AnCan – Rick sent: 4:00 PM

    Rohit Bose https://www.ucsfhealth.org/providers/rohit-bose

  • Steve L sent: 4:09 PM

    No time needed, Thank you.

  • Morgan Brooke sent: 4:17 PM

    I will share my journey if there is time. I don’t know if I was supposed to provide anything prior to the call

  • AnCan – Rick sent: 4:21 PM

    Morgan – you need to be here in the first 10 minutes as a Newbie. come back next week.

  • John Maxwell – Chicago sent: 4:22 PM

    John A, I do not need time tonight.

  • Steve Roux, Up North, Michigan sent: 4:26 PM

    I need to run – Great meeting guys!

  • Damon sent: 4:28 PM

    I need to drop off. Thanks for the advice on my case. I have a lot to think about. Hope to see you next time.

  • Jim Marshall, Vet Support Grp. Moderator sent: 4:31 PM

    Dr Channing Paller, GU Med Oncologist https://profiles.hopkinsmedicine.org/provider/channing-judith-paller/2706765

  • Alfredo in Wimberley, TX sent: 4:33 PM

    Good luck John B. I must ring off for tonight, best wishes to one and all! — Alfredo

  • Morgan Brooke sent: 4:36 PM

    Okay. I thought I was here in the first 10 minutes. I’ll be sure to join earlier next week. Thank you

  • Jim Marshall, Vet Support Grp. Moderator sent: 4:36 PM

    Jack. – welcome to the CLUB!!!!!

  • Jeff Marchi – San Francisco sent: 4:38 PM

    morgan too many new people today

  • Morgan Brooke sent: 4:38 PM

    Understood

  • Jeff Marchi – San Francisco sent: 4:40 PM

    get here 10 minutes before the meeting

  • Danny sent: 4:50 PM

    you looking for folks to speak?

  • Danny sent: 4:53 PM

    Jun 2022 PSA=4 (no actions taken) Nov 2025 PSA=13 Nov 2025 MRI PiRADs=5 Nov 2025 Biopsy Gleason 10 (5+5) Nov 2025 PSMA PET Local pelvic mets Nov 2025 No Genetic germline or somatic adaptations to treat Dec 2025 Started ADT (Nubeqa 1200mg + Orgovyx 120mg) daily Jan 2026 Blood Panel (PSA=0.45 T=11)

    Urology: R. Jeffrey Karnes, MD Onc: Elisabeth Heath, MD RadOnc: Anne Rajkumar, MD

  • AnCan – Rick sent: 4:58 PM

    Dr. Antonarakis https://med.umn.edu/bio/dom-a-z/emmanuel-antonarakis

Veterans Video Chat, March 3, 2026

Veterans Video Chat, March 3, 2026

by | Mar 5, 2026 | Health Resources, Recorded Groups, Veterans

Veterans Video Chat, March 3, 2026

Veterans Video Chat, March 3, 2026

AnCan is grateful to the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics, and Foundation Medicine.

If you missed any recent recordings, you’ll find the full list either on our YouTube Playlist or visit our Blog Post https://ancan.org/our-recent-blog-posts-in-case-you-missed-them/. Sign up for our Blog by checking the New Blog box at https://ancan.org/contact-us/.

AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussion are based solely on anecdotal peer experience or clinical evidence.

AnCan  cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500, https://www.fda.gov/media/76299/download/.

All AnCan’s groups are free and drop-in … join us in person sometime!

Join our other free and drop in groups:

Editor’s Pick: How to file a supplemental claim and preserve your original intent to file date. (bj)

Topics Discussed
How to file a supplemental claim to a denied disability claim and preserve your original intent to file date; neccesity of obtaining a nexus letter from a qualified medical professional when submitting a disability claim; new VA rules may lump tinnitus and hearing loss into a single 10% max disability rating; bring personal “statement in support of claim” documents (Form 21-4138) or even videos demonstrating physical limitations to C&P exams; procedures for getting a VA ID card; VA and private insurance processing; using “blanket” community care agreements to get access to specialized health care; retired veterans may apply for Combat Related Special Compensation (CRSC) if their disabilities are linked to combat, hazardous duty, training, or instruments of war.

Chat

Eric Baker – Lafayette, IN sent a chat · 9:14 PM
It was good to see everyone,…I just got home from a long business trip, and it is catching up to me.!  Have a good night gentlemen!  See   you on the 17th!

Bruce Schrimpf sent a chat · 9:34 PM
Good seeing all of you.  Good health to all!

Low/Intermediate PCa Video Chat, March 9, 2026

Low/Intermediate PCa Video Chat, February 23, 2026

by | Mar 5, 2026 | Cancer Caregivers, Cancer Resources, Low/Intermediate Prostate Cancer, Recorded Groups

Low/Intermediate PCa Video Chat, February 23, 2026

Low/Intermediate PCa Video Chat, February 23, 2026

AnCan is grateful to the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics, and Foundation Medicine.

WELCOME all to our newly recorded Low/Intermediate Prostate Cancer Group. To receive notice when new recordings are posted, either follow us on this YouTube Channel or sign up to our Blog via https://ancan.org/contact-us/ – check New Blog box.

Join our other free and drop in groups:
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime!

Editor’s Pick: Addressing the unusual: Low PSA with high-grade prostate cancer. (bj)

Topics Discussed
Importance of getting a second reading/opinion on your prostate cancer biopsy results; addressing the unusual: low PSA with high-grade prostate cancer; identifying risk factors that can push you from intermediate-risk to high risk prostate cancer; understanding how gentic testing help determine the best treatment options, espcially when family history exists; evaluating high-dose rate (HDR) brachytherapy as a primary treatment or boost to radiation; comparing transperineal and transrectal biopsies with a focus on lower risk infection and better patient experiences; determining when a patient should move from active surveillence (AS) based on rising PSA or new biospy results.

Chat

AnCan – Stuart sent a chat · 7:58 PM
Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881

AnCan – Stuart sent a chat · 7:59 PM
Dr. Jonathan Epstein – https://advanceduropathology.com/  Tel:516-760-2037    jepstein@imppllc.com

AnCan – Rick sent a chat · 8:04 PM
AnCan’s GU ASCO Poster released today   https://ancan.org/ancan-gu-asco26-survivorship-poster/

Norman Davis sent a chat · 8:13 PM
No. I’ve joined before but I havent joined in a while. I’m just listening tonight

Norman Davis sent a chat · 8:19 PM
Question is this  a call I should be on. I did have treatment 3 yrs ago

Norman Davis sent a chat · 8:20 PM
ok thanks

AnCan – Boykin sent a chat · 8:23 PM
@Norman Davis – I would stay and listen in. It doesn’t hurt and you are already here.

Norman Davis sent a chat · 8:23 PM
Gotcha. I  dont have a reoccurrence

Bill Franklin sent a chat · 8:31 PM
bfranklin@ancan.org

AnCan – Rick sent a chat · 8:49 PM
2nd Opinions for MRIs  Botimage AI for MRIs: https://botimageai.com/prostatid/ ~$250, can also be used for biopsy targeting guidance  NIH 2nd Opinion MRI (no fees): Choyke, Peter (NIH/NCI) Radiologist pchoyke@mail.nih.gov  Second opinion of MRI from Johns Hopkins Images and Reports for Providers | Johns Hopkins Radiology (hopkinsmedicine.org) Email: eradiologycenter@jhmi.edu Phone: 443-287-7378 Fax: 443-769-1210  -Accolade Radiology NY, PA https://accoladeradiology.com/mritap.html  Radiology Check (Switzerland) https://radiologycheck.com/en

AnCan – Rick sent a chat · 8:51 PM
Bx 2nd Opinions       Ep-stine! Dr. Jonathan Epstein – https://advanceduropathology.com/ Tel: 516-760-2037 jepstein@imppllc.com

AnCan – Rick sent a chat · 8:52 PM
Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881

Steve in Malaysia sent a chat · 8:58 PM
I need to head out at 10ish (5 minutes). I’ll followup with Rick and Stuart re: how to think about negotiating costs … I was quoted $100k for HDR and $180k for MR Linac.

Steve in Malaysia sent a chat · 9:01 PM
Also wanted to thank you guys (Rick, Stuart and company) on all your help on this crazy journey… could never had ended up where I did without your help 🙂

AnCan – Rick sent a chat · 9:04 PM
You need to make sure it registers with the Lead Mod.

Clyde sent a chat · 9:07 PM
Hey gang.  Gotta run.  I am graduating to the high risk group, so I will see some of you there.

AnCan – Boykin sent a chat · 9:08 PM
@clyde – Good luck. We will miss you in low/intermediate.

Bob Richards sent a chat · 9:09 PM
I would like to update the group tonight on my situation if possible

Norman Davis sent a chat · 9:21 PM
Good questions. I’ll rejoin next week. Thanks

AnCan – Boykin sent a chat · 9:23 PM
Good night Norman!

AnCan – Boykin sent a chat · 9:26 PM
Nice dog George!

David in Portland, OR sent a chat · 9:40 PM
Prostate Cancer Free Foundation Intermediate Risk graph: https://www.prostatecancerfree.org/compare-prostate-cancer-treatments-intermediate-risk/  High Risk graph: https://www.prostatecancerfree.org/compare-prostate-cancer-treatments-high-risk/

David in Portland, OR sent a chat · 9:41 PM
Prostate Cancer Free Foundation Low Risk graph: https://www.prostatecancerfree.org/compare-prostate-cancer-treatments-low-risk/

George in NC sent a chat · 10:04 PM
Thank you all and good night!  See you in 2 weeks!   Very grateful to AnCan especailly Rick and Stuart!

Larry (Alaska Vet) sent a chat · 10:05 PM
David, can you put a link to that 2024 study also, please?

Bill Franklin sent a chat · 10:05 PM
Good night George.

AnCan – Boykin sent a chat · 10:05 PM
Good night George

Steve in Malaysia sent a chat · 10:06 PM
back

David in Portland, OR sent a chat · 10:18 PM
Albert Chang & Peter Rossi brachytherapy video lecture: https://www.youtube.com/watch?v=QkfB5kkOsm4

[Waiting for name] sent a chat · 10:21 PM
Hi Leon here, trying to get back wit ya. Hit the wrong button

David in Portland, OR sent a chat · 10:22 PM
A Randomized Trial Comparing Quality of Life after Low-Dose Rate or High-Dose Rate Prostate Brachytherapy Boost with Pelvic External Beam Radiation (Crook, Juanita), 2024: https://www.redjournal.org/article/S0360-3016(24)00381-X/fulltext

David in Portland, OR sent a chat · 10:23 PM
A Randomized Comparison of High-Dose-Rate and Low-Dose Rate Prostate Brachytherapy Combined with External Beam Radiation Therapy for Unfavorable Prostate Cancer: Efficacy Results After Median Follow-Up of 74 Months (Crook, Juanita), 2025: https://www.redjournal.org/article/S0360-3016(25)00303-7/abstract

David in Portland, OR sent a chat · 10:24 PM
HDR Brachytherapy Combined with External Beam Radiotherapy for Unfavorable Localized Prostate Cancer: A Single Center Experience from Inception to Standard of Care (Crook, Juanita), 2025: https://www.brachyjournal.com/article/S1538-4721(25)00004-2/fulltext

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 3/10/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 3/2/26

by | Mar 4, 2026 | cardio-oncology, High Risk/Recurrent/Advanced, High Risk/Recurrent/Advanced Prostate Cancer, mCRPC, mHSPC, Prostate Cancer, Recorded Groups, Uncategorized

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 3/2/26

Listen to our recent Estradiol discussion https://ancan.org/learn-from-ancans-emperors-of-estradiol-021626/

Recent article on AnCan in Rarity life. https://ancan.org/rarity-life-magazine-featuring-rick-davis/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: AnCan’r considering AMG509 STEAP T-Cell engager; does IDC-P make you high risk?

Topics Discussed

Newbie needs GU MO and doublet; ADT and heart issues; BRCA2 germline Gent progresses after P; no evidence for doublet; long-timer needs to switch treatment; moving from Pluvicto to xaluritamig/ AMG509/ STEAP trial; supplemental E2 discussed by peer – insurance issues, gui9dance on E2 blood levels; IDC-P man on RT asks how much HT; with BCR, doubling time may be more significant guide to BCR than actual PSA level

Chat

  • Jim Marshall, Vet Support Grp. Moderator sent: 6:33 PM

    Genitourinary Medical Oncologist

  • Steve Schuler (Seattle) sent: 7:05 PM

    STRIKE-1 trial for KTX-2001

    https://www.urologytimes.com/view/fda-greenlights-phase-1-trial-of-nsd2-inhibitor-in-mcrpc

    https://www.nature.com/articles/s41586-025-09727-z

  • Bob Y — Los Angeles sent: 7:07 PM

    Have to leave early. Thanks, all.

  • Bruce Schrimpf sent: 7:08 PM

    Nice meeting, but must leave. BDS

  • Jim Stewart Reno, NV sent: 7:18 PM

    have to go pick up grandkids, good night all and thanks for the comments!

  • Steve Schuler (Seattle) sent: 7:25 PM

    https://erc.bioscientifica.com/view/journals/erc/24/8/ERC-17-0153.xml

  • AnCan – Rick sent: 7:27 PM

    Joining from the air. No mic available. I just blogged the Estradiol conversation.

  • AnCan – Rick sent: 7:36 PM

    Kishan would say 6 months per his recent meta study

    Show Tran the Kishan paper

  • Jeff Marchi – San Francisco sent: 7:37 PM

    has he had genetic testing? it can frequently be associated with genetic issues

  • AnCan – Rick sent: 7:37 PM

    12 months if you’re more aggressive.

    Is Spratt the final author

  • Steve Schuler (Seattle) sent: 7:40 PM

    I just wrapped it up a month ago. Now I’m on nothing, no ADT either. I was on Lupron for 2 years, abiraterone also for 2 years, but started a year after the Lupron started (there’s a story there, but later), and then on Estradiol for most of the time I was on abiraterone. But now on nothing. For most of the E2, it was .05mg (50 microgram) patches 2 per week. So a box of 8 lasts you 4 weeks. With GoodRX, those were $13/box

    A word about the dose level of the patches: that’s the estimated dose delivery of a patch per day. The amount of E2 in the patch itself is higher, something like 600 microgram is what I remember, but then it releases slowly at an ESTIMATED rate of 50. But that release rate is highly dependent on the amount of fat under the skin, etc. So your milage will vary

  • Mark N sent: 7:44 PM

    Thanks for the feed back!

  • dan-s alexandria sent: 7:48 PM

    thanks Jimmy

  • Pierre D., Olean, NY sent: 7:52 PM

    Thank you all for your input.

  • Jeffrey G sent: 7:53 PM

    We were in the 90s today. Ugh, warmest AZ winter i’ve ever been in. Still, gotta be grateful for warm weather and for a psa of 0.02…Adios

  • Steve Schuler (Seattle) sent: 7:54 PM

    I grade my energy on a curve

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 3/10/26

Learn from AnCan’s Emperors of Estradiol… PRICELESS video chat and discussion

by | Mar 2, 2026 | High Risk/Recurrent/Advanced, High Risk/Recurrent/Advanced Prostate Cancer, mCRPC, mHSPC, Prostate Cancer, Recent News, Recorded Groups, Uncategorized

Learn from AnCan’s Emperors of Estradiol… video chat and discussion

 

AnCan would bet no other prostate cancer support group has the experience and knowledge around using estradiol.

For those unfamiliar, estradiol is a female hormone that is found in men in small part; just like women carry a low level of testosterone (T). In large levels, estradiol (E2) can suppress T and effectively do the work of androgen deprivation, without many of the side effects of ADT. It is cheap and effective and has been around many years. So cheap that many pharmaceutical companies are concerned it can replace a primary, far more profitable ADT agent… like Lupron, Eligard, Firmagon or Orgovyx. Robert Reich, former Secretary of Labor, makes the argument better than I can.

It offers a much higher Quality of Life, and the recent PATCH trial has shown its efficacy and non inferiority. The major disadvantages are 1) getting a doctor to prescribe it since it is not FDA approved and must be prescribed off label. And 2) gynecomastia (breast enlargement) that can be painful and socially embarrassing, although it has remedies.

Two of the  most outspoken and well recognized advocates for E2 are peer users associated with AnCan. Dr. Paul Schellhammer, a former President of the American Urological Association, is on our Brains Trust. Dr. Richard Wassersug is on AnCan’s Advisory Board. Both have used E2 for more than 20 years, while AnCan member Al Latimer outlasts them both – but not together.

Listen to this outstanding discussion… yet again AnCan’s information is PRICELESS!

We have other E2 resources on our AnCan website: