Low/Intermediate PCa Video Chat, December 22, 2025

Low/Intermediate PCa Video Chat, December 22, 2025

AnCan is grateful to the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics, and Foundation Medicine.

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Editor’s Pick: Importance of getting your treatment at a NCCN Member Institution. (bj)

Topics Discussed
New quarterly support group for inherited mutations (e.g., BRCA, Lynch syndrome); eligibility for active surveillance despite a high-intermediate decipher score (0.57) and specific biopsy results (Gleason 3+4 with 10% grade 4); importance of obtaining a second opinion on biospy slides; importance of getting your treatment at a National Comprehensive Cancer Network (NCCN) Member Institution versus other medical institutions; nutrional and lifestyle approaches (e.g., fasting, ketogenic diets) before radiation; MRI-guided radiation (SBRT) and the experience of having fiducials and barriers implanted under local anesthesia; management of side effects like erectile dysfunction (ED) and the benefits of heavy exercise during long-term treatment; challenges faced by patients living abroad; concerns about inguinal hernia mesh repair complicating a future prostatectomy; lack of definitive ways to prevent prostate cancer; various theories regarding calcium levels.

Chat

AnCan – Stuart sent a chat · 8:02 PM
Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881

AnCan – Stuart sent a chat · 8:03 PM
Dr. Jonathan Epstein – https://advanceduropathology.com/  Tel:516-760-2037    jepstein@imppllc.com

AnCan – rick sent a chat · 8:12 PM
877 582 7011

AnCan – rick sent a chat · 8:13 PM
GoTo Technical Help

David K – Jacksonville FL sent a chat · 8:18 PM
aquablation and PAE: I’ll be asking if anyone has had an aquablation or a Prostate Artery Embolization. – david K

AnCan – rick sent a chat · 8:38 PM
We are looking at a spckof cancer here…. half a millimeter

AnCan – rick sent a chat · 8:39 PM
*speck of

Steve in Malaysia sent a chat · 8:41 PM
Does anyone have contact info for support staff of Dr Epstein as I’ve been trying to get slides to Stanford

Steve in Malaysia sent a chat · 8:41 PM
He has them now

Steve in Malaysia sent a chat · 8:43 PM
I did email him a few days ago but no answer

Frank H sent a chat · 8:43 PM
Try ask for Mary jones

Steve in Malaysia sent a chat · 8:44 PM
Thanks Frank, do you have her email?

AnCan Bill sent a chat · 8:44 PM
Steve, you can check his website: https://advanceduropathology.com/

AnCan Bill sent a chat · 8:44 PM
Frank did say he was on vacation for the holidays.

Steve in Malaysia sent a chat · 8:45 PM
My issue is more that I need to get my slides from him to Stanford soon as I’m going to US mid Jan

Frank H sent a chat · 8:47 PM
I will need to check with her myself tomorrow

Greg sent a chat · 9:04 PM
When does Medicare stop paying for Telehealth?

AnCan – rick sent a chat · 9:05 PM
Right around now, we beleive.

Greg sent a chat · 9:06 PM
For just prostate consults or across the board visits?

AnCan – rick sent a chat · 9:06 PM
Check on the internet, Greg

AnCan – rick sent a chat · 9:06 PM
Across tehe board.

AnCan – rick sent a chat · 9:16 PM
Cancer & Fasting UCSF  https://osher.ucsf.edu/patient-care/integrative-medicine-resources/cancer-and-nutrition/faq/cancer-and-fasting-calorie-restriction

AnCan – rick sent a chat · 9:17 PM
QiL fasting during chemo https://www.vumedi.com/video/esmo-2023-insights-effects-of-short-term-fasting-on-quality-of-life-as-an-add-on-option-during-chemo/?token=aea546f6-9f4e-41f5-98fd-3a2f2c6f6add&link_data=eyJiZXRfbWFpbF9pdGVtX2lkIjoyMDAwODM0MjQsImJldF9tYWlsX2FjdGlvbiI6ImJjIn0%3A1ryYHH%3A2ho3Ayar__FqeFstiJEPOgl60cTKcylOggsW5v-BNKQ&mc_cid=af2eade45f&mc_eid=838454d636

AnCan – rick sent a chat · 9:18 PM
Meta study from Kishan on ADT duration https://jamanetwork.com/journals/jamaoncology/article-abstract/2841671?guestAccessKey=d03b0908-90c8-497e-85cd-aebb43ec2a63&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jamaoncology&utm_content=olf-tfl_&utm_term=112025&mc_cid=0fa42784f6&mc_eid=838454d636

AnCan – rick sent a chat · 9:19 PM
Gil – also Spratt is on the metastudy.

Greg sent a chat · 9:20 PM
Which guys at Stanford?

Gil Solomon sent a chat · 9:34 PM
Thanks. I did see the ADT duration study and diminishing returns after 6 months

Gil Solomon sent a chat · 9:36 PM
Apalutamide study HEATWAVE and it is all comers regardless of cell type.

Gil Solomon sent a chat · 9:37 PM
I’m going to sign off for dinner.  Thanks all.

AnCan Bill sent a chat · 9:37 PM
Have a good night Gil

Steve in Malaysia sent a chat · 9:40 PM
Thanks for info Gil

AnCan – rick sent a chat · 9:43 PM
But we know that f you are Lumin A, apalutamide does not work.  Balance trial  https://ascopost.com/issues/october-25-2025/biomarker-driven-apalutamide-therapy-for-patients-with-recurrent-prostate-cancer/?mc_cid=17ff95d283&mc_eid=838454d636

Steve in Malaysia sent a chat · 9:47 PM
How long after last PSA read (was same time as MRI) should I get next one?

Steve in Malaysia sent a chat · 9:47 PM
That as Oct 12

Steve in Malaysia sent a chat · 9:47 PM
*was

AnCan Bill sent a chat · 9:50 PM
Steve, you’re 2 and a half months out from the last one but you don’t  have an urgent need to get PSA right now unless your doctor thinks you should.

Greg sent a chat · 9:51 PM
Will there be another email for donation?

AnCan – rick sent a chat · 9:51 PM
bfranklin@ancan.org

AnCan – rick sent a chat · 9:52 PM

Donate

Steve in Malaysia sent a chat · 9:52 PM
Thanks Bill, I’m a bit concerned as it went from 2.22 to 4.33 in 3 weeks

Steve in Malaysia sent a chat · 9:54 PM
I’ll ask Dr Sonn if needed before consult.

AnCan Bill sent a chat · 9:54 PM
When I was in your situation, I was getting it every 3 months at my doctor’s advice.

AnCan Bill sent a chat · 9:55 PM
Talk to your doc but remember, it can lead to increase anxiety.

Steve in Malaysia sent a chat · 9:55 PM
I understand re: anxiety

Steve in Malaysia sent a chat · 9:55 PM
I had an infection and was on cipro (but finished) right before last read.

AnCan Bill sent a chat · 9:58 PM
Ah, the infection could definitely be a contributer.

Steve in Malaysia sent a chat · 9:58 PM
oddly that infection was what lead to actual detection of cancer.

AnCan – rick sent a chat · 10:02 PM
Steve – the 4.33 could have a huge amount to do with the infection. I’d repeat the PSA sooner rather than later.

Steve in Malaysia sent a chat · 10:03 PM
ok, will do before I go to CA

AnCan – rick sent a chat · 10:04 PM
If it’s 2.33 what would you do, Steve?

Steve in Malaysia sent a chat · 10:05 PM
Hmmm…. not sure … I would still proceed with process I think given Epstein and Klotz recommendations.

AnCan – rick sent a chat · 10:06 PM
Stay in the moment!!!!

Steve in Malaysia sent a chat · 10:14 PM
Good luck with treatment Greg