Hi-Risk/Recurrent/Advanced PCa Video Chat, Nov 28, 2023

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Editor’s Pick: Advocating for what you want may not be advocating for what’s best for you. (bn)

Topics Discussed

PSA in the 60s, but Gleason 3+4 — time for a PSMA scan; SUV maxes of FDG PET and PSMA PET are unrelated and can’t be compared; don’t underestimate the chills and aches when starting zoledronic acid; Keytruda surpasses his expectations — a Christmas miracle? — but another man fails to respond; surprisingly good response after switching from daro to abi; docs agree to drop ADT — but advocating for what you want may not be advocating for what’s best for you; ADT is an easier ride when you’re knowledgeable and prepared; reminder: no cold turkey with prednisone; could monotherapy be a safer choice than ditching hard-to-tolerate ADT?; doc balks at genetic testing that could uncover therapy options

Chat Log

Richard Wassersug (Vancouver) · 6:09 PM
Myovant is now Sumitomo Pharma

AnCan – rick · 6:14 PM
Gleason Grade, right group????

Julian – Houston · 6:14 PM
I did read that Myovant got bought out!

Peter Kafka – Maui · 6:14 PM
He probably should be in the Low and Intermediate group.

Unknown · 6:24 PM
https://www.prostatecancerpromise.org/?utm_campaign=ANCAN&utm_medium=link&utm_source=Webinar

Steven Friedman · 6:31 PM
stevenfriedman55@yahoo.com

AnCan – rick · 6:36 PM
peterk@ancan.org

Peter Kafka – Maui · 6:37 PM
peterk@ancan.org

Peter Kafka – Maui · 6:44 PM
Sounds similar to Len’s experience recently.

Len Sierra · 6:44 PM
Almost identical to me.

Unknown · 6:44 PM
My wife Ellen had the same response she like you and Len

J. Ward · 6:59 PM
I made it an hour, gents, and wanted everyone to know about the Reclast side effects. I’m going to take Dr. John’s advice and hop off the call to get rest. Good night!

Len Sierra · 7:15 PM
From RADICALS-HD trial: After a median follow-up of 9 years, the study investigators found that 24 months of ADT were superior to 6 months (HR 0.77, 95% CI [0.61, 0.97]; 72% vs 78% at 10 years) with respect to the primary endpoint of metastasis-free survival (MFS).

Unknown · 7:20 PM
Why not try mono therapy first with Dara?

Larry Fish · 7:26 PM
please spell this drug-suppliment

AnCan – rick · 7:26 PM
fenbendazole

Jim Marshall, Melbourne, FL on Vac · 7:26 PM
I managed my ADT + Abi for 5 years and it did not slow me down. Being diagnosed at 73 and now 79 has slowed me down more. Aerobic Exercise has been the key even when my body said it was exhausted, will power got me on the bike which promoted recovery. jim

AnCan – rick · 7:48 PM
Elizabeth Heath Karmanos

AnCan – rick · 7:48 PM
https://www.karmanos.org/karmanos/karmanos-physician-directory/heath-elisabeth-8225

Frank Fabish Columbus OH · 8:00 PM
See you guys. good session.

Steve Roux, MI · 8:07 PM
Guys, really need some dinner; see you next meeting. Great session and thanks to all of you!

Len Sierra · 8:07 PM
BXCL701 showed good results when used with Keytruda in both enzalutamide resistatnt mCRPC and with small cell neuroendocrine cancer.

Len Sierra · 8:09 PM
Chromogranin A (CGA) and neuron-specific enolase (NSE) levels are biomarkers for NEPC. Also, they are synaptophysin positive