Pick of the Week …. long term monotherapy bicalutamide (Casodex)
Topic discussed
Mayo Clinic & Medicare reimbursement; PSMA scans vs starting ADT and salvage radiation on recurrence; USPSTF PSA recommndations result in advanced Dx and death; long-term monotherapy bicalutamide (Casodex); olaparib & CDK12; diet during salvage RT; novel abiraterone protocol; intervention after surgery; compassionate vs off label use; drug pricing after FDA approval; Richard Foody RIP
Chat Log
Peter Kafka : 3:41 PM: DR. Felix Feng at UCSF rad onc is amonst the best in the nation. Hard to get to him. He came from Michigan and is well known for his research in prostate cancer.
AnCan – Rick (to Peter Kafka): 3:55 PM: You are right – forgot about Felix. Best to let Borno direct him ….
Richard Stanton (to Everyone): 4:02 PM: Anyone who wants to chat offline please contact me. Thanks. (Ed. If you wish to discuss bicalutamide monotherapy, please contact info@ancan.org for Richard Stanton’s email address)
Editor’s Pick – Low PSA with high volume metastasis (rd) + successful treatment for ‘young’ man with de novo metastatic disease
Topics Discussed
de novo Mx with low PSA; clinical trial conflicts; biopsy sample from primary vs. Mx tumor; relevance of bone density tests; young de novo Mx man finds successful treatment; debulking the primary; when the end may not be the end!; bone biopsies; testing for PSMA avidity; PSMA scan availability in Covid times; testosterone swings; shipping delays for abiraterone; specialty pharmacies; what is the ‘doughnut’ hole?; abscopal/immuno effect from RT
Chat Log
scott (to Everyone): 5:05 PM: is this link the same link for all meetings?
Ken Anderson (to Everyone): 5:06 PM: scott yes this is the same meeting room
scott (to Everyone): 5:07 PM: 100 degrees isn’t fun…
Dell Jensen (to Everyone): 5:38 PM: Both Lupron and Docataxel
Dell Jensen (to Everyone): 5:43 PM: Rick is correct, treating the primary is critical
scott (to Everyone): 5:48 PM: is docetaxyl an infusion or a pill?
Dell Jensen (to Everyone): 5:48 PM: infusion
Ken Anderson (to Everyone): 5:49 PM: infusion once every three weeks
scott (to Everyone): 5:49 PM: do you do docetaxyl if the Zytiga I am on isn’t working?”
Ken Anderson (to Everyone): 5:49 PM: you can for sure do both at the same time…
scott (to Everyone): 5:51 PM: does the docetaxil have hard side effects?
Dell Jensen (to Everyone): 5:51 PM: osteoporosis is a result of ADT treatment
Dell Jensen (to Everyone): 5:51 PM: I definitely concur
Dell Jensen (to Everyone): 5:52 PM: my side effects were minimal, infections were my problems.
Ken Anderson (to Everyone): 5:52 PM: all chemo has side effects.. doce has some for sure and all are post on the web.
scott (to Everyone): 5:53 PM: thanks ken
Peter Kafka (to Everyone): 5:54 PM: I had a specialized genetic test from MIRA labs that gave me a risk assessment for developing a grade 2 or greater adverse reaction to PD1/PDL1 agent therapy.
Russ Smith (to Everyone): 6:28 PM: Good night all. It’s been a long day.
scott (to Everyone): 6:31 PM: is david muslin head of answer cancer foundation?
Len (to Everyone): 6:35 PM: No, Rick is head of AnCan
scott (to Everyone): 6:36 PM: I sent a donation to ancan fdn in honor of rick and have heard nothing
Len (to Everyone): 6:36 PM: It will be acknowledged soon, if in fact they received it properly.
scott (to Everyone): 6:37 PM: thanks…just want to make sure rick is honored by donation
scott (to Everyone): 6:39 PM: is speaking freely 8 pm az time?
Rich Jackson (to Everyone): 6:43 PM: Speaking Freely starts at 8pm EST.
scott (to Everyone): 6:43 PM: thanks
Rich Jackson (to Everyone): 6:43 PM: Same connection as this call.
scott (to Everyone): 6:53 PM: who is the gentleman now speaking?
Dell Jensen (to Everyone): 6:53 PM: Correia
Dell Jensen (to Everyone): 6:55 PM: Are there other compounding pharmacy?
Dell Jensen (to Everyone): 6:57 PM: I have local one that is in Rock Island, IL
Pick of the Week: Do academic GU med oncs have a clinical trial conflict of interest?
Topics Discussed
Finding a quarterback GU med onc in Pennsylvania; do academic GU med oncs have a trial conflict of interest?; no prednisone with chemo; what mutation drives your PCa; gynecomastia remedies; is too much succes from a 2nd line HT a bad thing?; Dr. Daniel Petrylak @ Yale; how do you follow up your RT/SBRT?; painful Lupron shots; generic abiraterone co-pay assistance
Chat Log
scott (to Everyone): 3:31 PM: could you spell that again…the gumedical oncologist?
Len (to Everyone): 3:31 PM: genitourinary
Len (to Everyone): 3:31 PM: genito-urinary medical oncologist
Peter K : 3:38 PM: Allentown to MSK in Bedminster, NJ is only 1 hour drive. Same distance and time to Philly.
Peter K : 3:52 PM: Roswell Park is not far from Rochester
scott (to Everyone): 3:54 PM: how do you spell and what is something lilke “sabozitaxil” she is referring to? anyone?
Len (to Everyone): 3:55 PM: cabazitaxel
Len (to Everyone): 3:55 PM: It’s a form of chemotherapy very similar to docetaxel
scott (to Everyone): 3:55 PM: how do you spell it? thanks
Len (to Everyone): 3:59 PM: cabazitaxel
Len (to Everyone): 4:00 PM: trade name is Jevtana
scott (to Everyone): 4:03 PM: my big question tonight, if I get to ask, is what is best foundation or group for financial assistance with Zytiga copays?
Len (to Everyone): 4:10 PM: Scott, go here: https://www.janssencarepath.com/patient/zytiga/cost-support
scott (to Everyone): 4:15 PM: Janssen won’t help if you have Medicare
Pick of the Week – not too exciting folks, but an important discussion on radiation procitis that we rarely have! rd
Topics Discussed
Treatment choice for hi-risk Dx; when is oligometastatic no longer?; risks of Keytruda + Xtandi trial vs cabazitaxel; clinical trial conflict of interest; success with dutasteride; radiation proctitis – pentoxifylline, argo laser, hyperbaric Tx?; Intermittent Hormone Therapy – risks and rewards; abscopal effect from spot RT;
Bill Franklin (to Everyone): 5:17 PM: Highly recommend the nexverse.org COVID-19 Summit @ https://www.crowdcast.io/e/nextopic-future-of-pandemics. Lots of interesting things about viruses, vaccines, and future treatments.
Ken Anderson (to Everyone): 5:18 PM: thanks Bill…
Ken Anderson (to Everyone): 5:18 PM: will have a look!
Bill Franklin (to Everyone): 5:19 PM: Just above the video window is a small drop down menu where you can select the different presentations. It’s kind of hard to see.
AnCan – Rick (to Everyone): 5:21 PM: prostatecancerinfolink.net/2015/03/12/ebrt-ldrbt-boost-provides-superior-cancer-control-compared-to-ebrt-alone/#comment-152149
AnCan – Rick (to Everyone): 5:34 PM: http://urology.ucsf.edu/sites/urology.ucsf.edu/files/uploaded-files/attachments/hormone_therapy_for_prostate_cancer_a_patient_guide_2.pdf
AnCan – Rick (to Everyone): 5:35 PM: https://smile.amazon.com/Androgen-Deprivation-Therapy-Second-Essential/dp/0826183913/ref=dp_ob_title_bk
Len (to Everyone): 5:36 PM: http://www.lifeonadt.com/
Len (to Everyone): 6:44 PM: Pentoxifylline
scott (to Everyone): 6:55 PM: does this group generally meet 1st and 3rd Mondays or other times as well?
Pick of the Week: First and last this week ….. prednisone may have optical side effects; and, using Lu177 very early in the metastatic disease cycle.(rd)
Prednisone side efects on eyes and more; Covid19 making you stir crazy?; Doctor/lab visits during Covid19; Getting treated home and away; Xgeva users survey pays well; getting used to ADT; starting salvage radiation; should a GU med onc lead your team?; very early Lu177 vs hormone therapy
AnCan – Rick (to Everyone): 4:17 PM: len@ancan.org
AnCan – Rick (to Paul Freda): 4:58 PM: We see ya …. looking v. good w/o a moustache!!
Paul Freda (Private): 4:59 PM: Oh gosh I have not had a mustache for years. Maybe when I was living in Bangkok 5 yrs ago. ??
Paul Freda (Private): 5:02 PM: My blood test came back in one day. Cheers … still in remission.
AnCan – Rick (to Paul Freda): 5:05 PM: Yeah …….
AnCan – Rick (to Paul Freda): 5:07 PM: We’ll get to you next week -promise
Paul Freda (Private): 5:08 PM: No problem. I was just going to mention a great documentary on Jim Allison, the Nobel Prize winner who is now at MD Anderson. He is responsible for many CURES with Ipilimumab. Really interesting guy.
