Hi-Risk/Recurrent/Advanced PCa Video Chat, Jan 28, 2025
Made a donation yet? If not, now’s the time – PLEASE! It’s AnCan’s Annual Fundraiser – once a year is the only time we ask for donations.
We’ve received less than 10% from participants, viewers and those receiving the Reminder combined. Time to step up and show appreciation and gratitude if you watch these videos, find them helpful., and want them to continue. Donate now at https://ancan.org/donate/
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix & Blue Earth Diagnostic.
- You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/
- Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
- Under 60 Stage 3&4 Prostate Cancer – 2nd Thursdays @ 7pm Eastern in AnCan Barniskis Room
- Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
- Veterans Healthcare Navigation… 4th Thursday @ 8.00 pm Eastern https://ancan.org/veterans
Editor’s Pick: After 10 years (with a Gleason 10!) he’s ready for an ADT break. (bn)
Topics Discussed
Just three positive biopsy cores — but they’re in a bad place; five positive cores — but they’re all Gleason 3+3; he’s “an 81-year-old guy who’s been fighting cancer for 10 years” (with a Gleason 10!) and is thinking about a drug holiday; reminders from Rick: donations are still sadly low, and there’s still time to fill out the survey; re-irradiate old metastases that no longer show up in scans?; my docs don’t talk to each other — you’re calling that a team?; he’s never had a seizure till now — was it the Xtandi, and was it really a seizure?; should he fine-tune which statin he takes?; is prostate debulking useful for de novo men?; does he also need spot radiation in his bones if he’s also getting ADT?; those new bone pains might be caused by metastasis, not ADT; his urologist and the MSK nomogram are way apart on prognosis.
Chat Log
Len Sierra · 6:39 PM
https://www.mskcc.org/nomograms/prostate
AnCan – rick · 7:02 PM
PROMISE trial https://www.prostatecancerpromise.org/?utm_campaign=ANCAN&utm_medium=link&utm_source=Webinar
AnCan – rick · 7:29 PM
Survey …. https://docs.google.com/forms/d/e/1FAIpQLSfw2B3rZTMWIPqTmzLYBl1CdN9qRJSpt0f72CoK6J00zllzWw/viewform
AnCan – rick · 7:30 PM
Donations https://ancan.org/donate/
AnCan – rick · 8:06 PM
Study Doug is ref: https://pmc.ncbi.nlm.nih.gov/articles/PMC3255347/#abstract1
Dr. Jeff · 8:09 PM
According to current research, rosuvastatin appears to be more effective than simvastatin in potentially preventing or managing prostate cancer based on studies showing a stronger association with reduced cancer progression and mortality, with some evidence suggesting that rosuvastatin may have a more potent anti-tumor effect compared to simvastatin; however, more research is needed to fully understand the specific differences between the two drugs in relation to prostate cancer. Several studies have indicated that rosuvastatin may be associated with a greater reduction in prostate cancer mortality compared to simvastatin. So there are different conclusions.
AnCan – rick · 8:15 PM
Allen Edel https://pcnrv.blogspot.com/2018/09/no-survival-benefit-to-debulking.html
Larry Schuller · 8:30 PM
Firmagon and Orgovyx are receptor antagonists. Lupron is an agonist. They interrupt the instructions to the testes to make testosterone but agonists have two problems. The first is a testosterone surge (which has to be endured or suppressed) for about amonth and the second is that when you stop, it takes longer for your testosterone to recover
AnCan – rick · 9:03 PM
gdeliguori@imppllc.com
Jim Marshall, Alexandria, VA · 9:04 PM
Ming Zhou – Ming.zhou@mountsinai.org