Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 17, 2025

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Editor’s Pick: Assessing recurrence and IDC-P repeat this week.

Topics Discussed

Signs of recurrence after 8 years; lymphedema and RT; does Newbie understand his proposed RT – is it optimal?; signs of BRCA2 recurrence post RP; doublet or triplet for denovo Mx Gent with IDC-P; explaining types of HT treatment; likely PSMA negative Gent challenged to confirm recurrence; PSA spike & fall for IHT man; fatigue after ARSI is added; estradiol supplement experience; pushing exercise helps mitigate HT; IDC-P teatment challenge – RP vs RT; bisphosphonate vs denosumab as bone strengthener

Chat

Larry (Alaska)

sent: 6:17 PM

Was there a decipher test? indicating aggressiveness?
Larry (Alaska)

sent: 6:24 PM

I wonder how old those NIH studies Barbara and Joe are reading?
Eric James; Tyler TX

sent: 6:29 PM

https://pmc.ncbi.nlm.nih.gov/articles/PMC9688147/
Eric James; Tyler TX

sent: 6:31 PM

The higher rates of lymphedema are after pelvic irradiation following lymph node dissection
AnCan–John A

sent: 6:31 PM

Thx Eric
Bob Y. Los Angeles

sent: 6:34 PM

Question: for a Decipher Prostate Test… how do I get that genomic test? Does my doctor order it or what?
AnCan – rick

sent: 6:35 PM

Sandy Liu https://www.cityofhope.org/sandy-liu
Eric James; Tyler TX

sent: 6:35 PM

Bob Y. Yes, generally done from your biopsy tissue
Jim Marshall, Veteran, Alexandria, VA

sent: 6:35 PM

There is Germline test and Somatic Test nothing to do with Decipher. Jim
Bob Y. Los Angeles

sent: 6:38 PM

Thanks. I’ll ask my urologist to run the Decipher test from my biopsy tissue.
Jeff Marchi – San Francisco

sent: 6:43 PM

get genetic test free here
Jeff Marchi – San Francisco

sent: 6:43 PM

https://www.prostatecancerpromise.org/?utm_campaign=ANCAN&utm_medium=link&utm_source=Webinar
Luther Blake

sent: 6:46 PM

have to run gents, have a good evening
AnCan – rick

sent: 5:57 PM

GoTo technical support 877 582 7011
AnCan–John A

sent: 6:48 PM

ming.zhou@mtsinai.org, or https://profiles.mountsinai.org/ming-zhou OR
AnCan–John A

sent: 6:49 PM

advanceduropathoogy.com 516 280 7930
Jeff Marchi – San Francisco

sent: 6:53 PM

while that email may work I got a different address
Jeff Marchi – San Francisco

sent: 6:53 PM

Send an email to Ming.zhou@mountsinai.org to inquire about a second opinion and ask for his specific instructions for the process.
Jim Stewart Reno, NV

sent: 7:07 PM

have to sign off, thanks all and have a good night
Jon McPhee Toronto

sent: 7:33 PM

Have to go. Thanks for the meeting.
Larry (Alaska)

sent: 7:37 PM

AI just told me that 1- micro-ultrasound does not require a contrast dye and uses equipment that is more accessible than MRI. 2- Other than that, they seem to be seen as complementary rather than competing. MRI is better at detecting some lesions and micro-ultrasound better at others.
Stan Friedman

sent: 7:48 PM

Sorry. Need to sign off. Will update on my pluvicto treatments next week. Thanks.
Jim Marshall, Veteran, Alexandria, VA

sent: 7:53 PM

Chocolate is a veggie!!!!!! Jim
TonyFig

sent: 7:53 PM

Rick will get a 3 knot boost when rowing with caffeine
St

sent: 7:56 PM

my experience has been that the fatigue comes mainly from lack of estrogen, not from the lack of T. An E2 patch helped me enormously
Bob Y. Los Angeles

sent: 7:57 PM

I had a couple of short questions, but I have to leave now. I’ve had an MRI and a biopsy, Gleason 4+5. I’m waiting to get a PET Scan on Dec 5th. I was hoping to get the PET earlier and so I made an appt with a urologic oncologist, Timothy Daskivich for a 2nd opinion on Nov 26th. Now I’ll be going to see him without being able to show him the PET results. I’m wondering if that appt is still valuable.
Barbara and Joe

sent: 7:59 PM

why do you have to take something as toxic as prednisone with abiraterone?
Don Rogers

sent: 8:00 PM

got to go
Eric James; Tyler TX

sent: 8:00 PM

Barbara and Joe: side effects of abiraterone. Your body stops producing cortisol on abiraterone so it needs to be replaced with something similar.
AnCan–John A

sent: 8:00 PM

Barbara and Joe the body absolutely needs the corticosteroid.
Jim Marshall, Veteran, Alexandria, VA

sent: 8:01 PM

Abi stops the Adrenal Glands which makes Cortisol. Presidnsone makes the Cortisol.
Jim Marshall, Veteran, Alexandria, VA

sent: 8:02 PM

One needs Cortisol. Jim Marshall
AnCan – rick

sent: 8:10 PM

Estradiol seminar w. Steve S https://ancan.org/talking-estradiol-e2-for-recurrent-and-advanced-prostate-cancer/
Keith H. (southern Oregon)

sent: 8:15 PM

thanks for all this, I got to go, but grateful for expertise and this group.
Thomas Matica

sent: 8:21 PM

Short update. Can wait till next meeting. Got to run. Thanks everyone.
Barbara and Joe

sent: 8:23 PM

I hope it’s a low dose of predisone — it just about killed my mother with her rheumatoid arthritis.
Jim Marshall, Veteran, Alexandria, VA

sent: 8:23 PM

5mg of Prednisone is used. Jim M
Jim Marshall, Veteran, Alexandria, VA

sent: 8:24 PM

Although once you stop it one still should taper off versus Cold Turkey. Jim
Steve White

sent: 8:28 PM

Have to drop…thanks again
Alfredo in Houston, TX

sent: 8:35 PM

I must drop off now, thank you everyone; stay well.
Mark N

sent: 8:42 PM

Thanks!!
Barbara and Joe

sent: 8:43 PM

thanks so much everybody.

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 17, 2025