Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 25, 2025

Happy Thanksgiving to all our AnCan particpants, especially if not on our mailing list. We’d have to ask why not, when you can sign up at https://ancan.org/contact-us/ and recive our great Newsletter/Reminder.

CORRECTION (rd)

I want to apologize and make a correction for someting I said in last Tuesday’s support group. At the end we were discussing adding a couple of Pluvicto treatments to Metastatic Directed Therapy. However this was for a man who had progressed rather than having just been diagnosed oligometastatic as in the LUNAR trial reported in the Reminder last week. I mentioned he might be eligible in the USA as Pluvicto is approved for metastatic hormone sensitive prostate cancer. This is not the case, and I misspoke. PSMAddtion was positively reported for mHSPC use at the recent ESMO conference – thank you Dr. Paul for this link. To date, it has not been FDA approved. I knew of the trial and got ahead of the game; although I was confusing it with PSMAFore.

AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Robust discussion around testoterone early on – and thoughts about combining therapies at the end.

Topics Discussed

how long to stay on HT leads to rich discussion on testosterone; did salvage cryo bring his PSA down? And he needs a GU MO QB; cupplementing T with Clomid is new to AnCan; casting around for intial treatment; ststarting Prolia that’s NO lifetime drug; tachycardia and AFib; recovering from 6x dicetaxel; b est treatment options for Stage T3 ; holding steady; allowing PSA to rise to find source of oligo-Mx; can we add Pluvicto to MDT later in the cycle?

Chat

Frank Ciambra sent: 5:10 PM

my wife is a nurse working in cardiology ,im going to share this witth her
John M – Chicago sent: 5:11 PM

Don I am doing great. Feeling stronger. Exercise is the KEY. Everything progressing according to plan. I’m going to my sons house to be with him, his wife and my grandson. What about you?
Jim Marshall, Veteran, Alexandria, VA sent: 5:27 PM

AFib – Join the club with others. Jim Marshall
Julian – Houston sent: 5:29 PM

I had AFIB then had cardiac ablation in March 25 and then it went away!
Jim Marshall, Veteran, Alexandria, VA sent: 5:30 PM

AFib is Mutually exclusive with Vitamin K. Jim Marshall;
Jim Marshall, Veteran, Alexandria, VA sent: 5:32 PM

Have AFib and take Blood Thinner, Pradaxa, Metropolol Tartrate and a Statin – Pravastatin. Jim Marshall
AnCan – rick sent: 5:33 PM

abir-A-terone
Jim Marshall, Veteran, Alexandria, VA sent: 5:34 PM

Lupron/Eligard and Abi have warnings for those who have heart issues. Jim Marshall
Alfredo in Houston, TX sent: 5:37 PM

Vitamin K potentially interferes with anticoagulants (blood thinners). And you also get vitamin K in your diet from leafy greens. Everyone please remember to discuss ALL supplements with your physician AND pharmacist.
TonyFig sent: 5:39 PM

There is a strong link between sleep apnea bringing on A-Fib.
Alfredo in Houston, TX sent: 5:41 PM

I am being called to supper now, so I must leave — but not before wishing a Happy Thanksgiving to everyone. Good night
AnCan–John A sent: 5:48 PM

stereotactic body radiation therapy
Julian – Houston sent: 5:53 PM

Happy Thanksgiving to all!!!
TonyFig sent: 5:56 PM

Blood Thinner – a naturopath approach for anticoagulation can be quite risky as it may not present consistent and reliable levels to address A-Fib episodes or other cardiac issues. I discussed this with cardiac surgeons as well as a heart biologic replacement valve supplier. I would not take the risk of naturopath solution for this application.

Nattokanese, Vit E, Ginger, Omega Oils in high dose, Cayene Pepper Tumeric, etc
John M – Chicago sent: 6:04 PM

Have a great Thanksgiving everyone!
Dennis Correia sent: 6:07 PM

Happy Thanksgiving all
Barry Blomquist sent: 6:07 PM

Have to jump – Happy Thanksgiving to everyone and thank you all!
dan-s sent: 6:09 PM

Thanks all – Happy Thanksgiving
Jerry Pelfrey sent: 6:10 PM

Time to go. Everyone have a wonderful Thanksgiving.
Larry (Alaska) sent: 6:14 PM

Suggesting Pluvicto as first-line treatment instead of ADT as first-line?
Bob Y — Los Angeles sent: 6:15 PM

Thank you, all, for your good counsel.
David Muslin sent: 6:17 PM

Gobble Gobble love you guys

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 25, 2025