“Playing the Long Game” – Does your Recurrent/Advanced Prostate Cancer Need Treating? NCI Seminar
by Rick Davis | Jan 30, 2026 | High Risk/Recurrent/Advanced, High Risk/Recurrent/Advanced Prostate Cancer, Low/Intermediate Prostate Cancer, mCRPC, mHSPC, nmCRPC, Recent News, Recorded Groups, Uncategorized, Webinars
“Playing the Long Game” – Does your Recurrent/Advanced Prostate Cancer Need Treating?
National Cancer Institute Seminar with Dr. Ravi Madan and Dr. Melissa Abel , Jan 30, 2025
READ THROUGH – you won’t regret it!! (rd)
AnCan has long been perplexed by the prostate cancer category “non-metastatic Castrate Resistant” or even “non-metastatic Hormone Sensitive”. If PSA is rising after primary treatment but prior to hormone treatment, something’s going on however ‘micro-metastatic’. It’s like being just a little bit pregnant!!
This paper considers a new category PSMA Positive Biochemically Recurrent – PSMA+ BCR. We circulated the paper to our Brains Trust and reached out to Dr. Ravi Madan at the National Cancer Institute (NCI) with a couple of questions. Dr Madan offered to meet with us along with his colleague, Dr. Melissa Abel. What resulted was this REMARKABLE video that could present many of our recurrent and advanced AnCan (& non-AnCan) participants with one of the most mind blowing videos many have seen in a long time,
DO YOU REALLY NEED TREATMENT??
As the venerable and highly respected Dr. Paul Schellhammer said in the meeting, “it’s like listening 15 years ago to the folks who began to promote active surveillance ( in first line treatment)” Dr. Madan and Dr. Abel have collected solid data from around 150 patients that suggests men with slow PSA doubling times can “play the long game” as Dr. Ravi calls it, and defer active treatment when their disease recurs.
PLEASE watch this astonishing presentation, listen to some excellent observations and questions, and consider how it relates to your own situation. And spread the word to others. Dr. Madan’s and Dr. Abel’s NCI clinical trial can be found at https://www.clinicaltrials.gov/study/NCT05588128 . Don’t immediately assume you’re not eligible before speaking with them… but you’ll have to watch the video to get their contact information.
Watch the video https://youtu.be/v4jzyAeOtNI
