Hi-Risk/Recurrent/Advanced PCa Video Chat, May 19, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 19, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 19, 2025

It’s GreatNonProfits time of year for AnCan participants! Each year we need 10 new endorsements to retain our GreatNonProfits Seal, so if you’re relatively new &/or have not endorsed us previously, now’s the time. Just click https://greatnonprofits.org/org/ancan-foundation and tell the short version of why you love AnCan Foundation…. THANK YOU!
President Biden’s Diagnosis
Exceptionally, the Moderators dedicated a few minutes at the beginning of the session to discuss Joe Biden’s denovometastatic hormone sensitive prostate cancer diagnosis disclosed late last week. AnCan recognizes that most of our particpants directly relate. Start around the 20 minute mark if you prefer to skip Rick Davis’ statement and reactions to President Biden’s diagnosis from those present.
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix, Blue Earth Diagnostic and Foundation Medicine.
If you missed any recent recordings, you’ll find a full list either on our YouTube Playlist or visit our Blog Post https://ancan.org/our-recent-blog-posts-in-case-you-missed-them/   Sign up for our Blog by checking the New Blog box at https://ancan.org/contact-us/
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime!
Join our other free and drop in groups:

Editor’s Pick: President Biden’s diagnosis; and, ctDNA testing (rd)

Topics Discussed

President Biden’s mHSPC Dx; younger T3b Newbie faces treatment decision; is ctDNA testing available to patients?; 3rd Pluvicto treatemtn brings heavy side effects; what to expect 2 months after starting a drug holiday; Orgovyx appeal continues; Gent with seizure/cardio issuestakes drug holiday and needs a cardio-oncologist; lowPSAl, pre-chemo Gent starts Pluvicto; should Gent with adrenal insufficiency add 5 mg prednisone?

Chat Log

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 19, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 13, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 13, 2025

It’s GreatNonProfits time of year for AnCan participants! Each year we need 10 new endorsements to retain our GreatNonProfits Seal, so if you’re relatively new &/or have not endorsed us previously, now’s the time. Just click https://greatnonprofits.org/org/ancan-foundation and tell the short version of why you love AnCan Foundation…. THANK YOU!
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix, Blue Earth Diagnostic and Foundation Medicine.
If you missed any recent recordings, you’ll find a full list either on our YouTube Playlist or visit our Blog Post https://ancan.org/our-recent-blog-posts-in-case-you-missed-them/   Sign up for our Blog by checking the New Blog box at https://ancan.org/contact-us/
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime!
Join our other free and drop in groups:

Editor’s Pick: Pluvicto shows results after 2 treatments (rd)

Topics Discussed

Surgery vs RT choice for high risk Newbie; PARP failing BRCA1 Gent – what next .. 2nd opinion!; 6-wk testing schedule leads to stable PSA; doing well post recurrence treatment; argon laser beats hyperbaric chamber to treat RT proctitis for our USN diver; Dr. Oh says wait on HT; GU MO in S. Florida; Jevtana holds advnced disease but kidney causes hospitalization; GU MO recommendation at Langone, Madison; unclear recurrence needs Dr. Heath’s eye at Mayo, Rochester.

Chat Log

  • AnCan – rick sent: 4:17 PM

  • Len Sierra sent: 4:37 PM

    Phase 2 study of ADT vs. darolutamide monotherapy: https://pubmed.ncbi.nlm.nih.gov/38272747/

  • Jim Marshall, Alexandria, VA sent: 4:54 PM

    It is called “Testosterone Flair”.

  • Julian – Houston sent: 4:55 PM

  • Jim Cavanaugh sent: 4:58 PM

    Gleason 8 90% of most of 12 cores. on oqgovyx. Prayers to all. Could not figure lock icon in browser

  • AnCan – rick sent: 4:59 PM

    GoTo Helpline 877 582 7011 222-583-97

  • Jim Cavanaugh sent: 5:00 PM

    yes. have been on with Ron Ferraro. Chaplain Jim

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 19, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 5, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 5, 2025

AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix, Blue Earth Diagnostic and Foundation Medicine.
If you missed any recent recordings, you’ll find a full list either on our YouTube Playlist or visit our Blog Post https://ancan.org/our-recent-blog-posts-in-case-you-missed-them/   Sign up for our Blog by checking the New Blog box at https://ancan.org/contact-us/
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime!
Join our other free and drop in groups:

Editor’s Pick: How to follow PARP-I for BRCA1 Gent (rd)

Topics Discussed

Setting up for recurrence treatment in Alberta, Canada; PSMA rules out Mx, but what about other pelvic issues – bone Bx to follow; debulk IMRT done – SBRT boost to follow; 2 Pluvicto sessions reveal good progress; 90 days max for vacay meds on Medicare; is darolutamide monotherapy enough?; will new test to replace PSA work for recurrence?; how long to PSA nadir on HT?; Tricare alone not enough – join Vets to learn how to dual enroll; Payer denies Orgovyx – what to do; Marine Chaplain can’t find his voice – so uses Chat!

Chat Log

AnCan – rick sent: 4:17 PM

https://howardwolinsky.substack.com/

Len Sierra sent: 4:37 PM

Phase 2 study of ADT vs. darolutamide monotherapy: https://pubmed.ncbi.nlm.nih.gov/38272…

Jim Marshall, Alexandria, VA sent: 4:54 PM

It is called “Testosterone Flair”.

Julian – Houston sent: 4:55 PM

https://www.orgovyx.com/cost-and-support

Jim Cavanaugh sent: 4:58 PM

Gleason 8 90% of most of 12 cores. on oqgovyx. Prayers to all. Could not figure lock icon in browser

AnCan – rick sent: 4:59 PM

GoTo Helpline 877 582 7011 222-583-97

Jim Cavanaugh sent: 5:00 PM

yes. have been on with Ron Ferraro. Chaplain Jim

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 19, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, April 22, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, April 22, 2025

AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix, Blue Earth Diagnostic and Foundation Medicine.
If you missed any recent recordings, you’ll find a full list either on our YouTube Playlist or visit our Blog Post https://ancan.org/our-recent-blog-posts-in-case-you-missed-them/   Sign up for our Blog by checking the New Blog box at https://ancan.org/contact-us/
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime!
Join our other free and drop in groups:

Editor’s Pick: If you’re thinking Pluvicto, consider TLX591 (rd)

Topics Discussed

Younger Newbie concerned how to speak with his teenager; doublet or triplet for Canadian; Capt. Jim appreciates Dr. John’s heart intro; rising PSA remains a mystery; if you’re thinking Pluvicto, consider TLX591; remission continues thanks to AnCan; concerned about tentacular involvement; just home from HDR brachy

Chat Log

  • AnCan – rick sent: 3:27 PM

    Telix RLT pre-chemo trial. TLX 591 https://clinicaltrials.gov/study/NCT06520345?term=NCT06520345&rank=1#participation-criteria Not listed but I think it’s available in NYC

    Just checked and TLX591 is at Columbia.

  • Len Sierra sent: 3:45 PM

    docetaxel trade name is Taxotere.

  • Jim Marshall, Alexandria, VA sent: 4:14 PM

    Been taking 100mg in the morning and 200mg at night of B6. Took about 6 weeks to kick in. Jim

  • david opp sent: 4:15 PM

    I take B12 and was told to also take Alpha Lipoic Acid and the Neuropathy has reduced since taking these 2.

  • Steve Roux, North Michigan sent: 4:49 PM

    I need to go. See you guys next week!

  • Gary V Portland, Oregon sent: 4:57 PM

    I have to go as well thanks for a great session..

  • Bob Schwartz, USN, Venice FL sent: 4:58 PM

    Switching over to the other mtg.

  • Doug, Portland, Or sent: 5:01 PM

    Heading over to Vets Speaking Freely. Thank you for the great meeting.

  • Robert Boghosian sent: 5:11 PM

    Need to sign off. Thank you.

  • Thomas M sent: 5:16 PM

    Got to scoot. Thanks for a great meeting.

Hi-Risk/Recurrent/Advanced PCa Video Chat, May 19, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, April 8, 2025

Hi-Risk/Recurrent/Advanced PCa Video Chat, April 8, 2025

AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix & Blue Earth Diagnostic.
If you missed any recent recordings, you’ll find a full list either on our YouTube Playlist or visit our Blog Post https://ancan.org/our-recent-blog-posts-in-case-you-missed-them/   Sign up for our Blog by checking the New Blog box at https://ancan.org/contact-us/
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime!
Join our other free and drop in groups:

Complete Richard Wassersug’s E2/estradiol survey – open to all https://qualtricsxmxjhxcwlhx.qualtrics.com/jfe/form/SV_2h2GxUXB1lWMT9I

Editor’s Pick: Testosterone superman deflates — and his shrine is dismantled — after he checks his math (bn).

Topics Discussed

Will a switch to estrogen outsmart the cancer?; he was slated for 3 years of ADT, but may want to quit or or ease off on year 3 — many options exist but not all are proven; third Pluvicto round for Marc V — he’s looking well, and Dr. Aggarwal’s feeling good about the results; the right way to taper off a bone strengthener; the story of CD46, a promising PCa marker for theranostics; spotlight’s back on hot flashes — as usual, many suggestions; he wants to resume his job the day after brachy — possible?; cardio-oncologist in Chicagoland?; testosterone superman deflates — and his shrine is dismantled — after he checks his math; off ADT, should he worry about rising T?; too early in the game for neuroendocrine worries; even if you need to wait for a scan, don’t start ADT without one; don’t sweat the small stuff when it comes to rising PSA; insufficiency fractures; what to expect during radiation treatment — Dr. Mark’s the expert.

Chat Log

AnCan – rick · 6:41 PM
How Cancer Cells Travel to New Tissues and Take Hold… https://www.medscape.com/s/viewarticle/how-cancer-cells-travel-new-tissues-and-take-hold-2025a10007rt?ecd=WNL_trdalrt_pos1_250407_etid7346797&uac=529807HK&impID=7346797

AnCan – rick · 7:02 PM
Embr WAVE

Len Sierra · 7:02 PM
Embr Wave 2

Steve Roux, North Michigan · 7:09 PM
oxybutynin for hot flashes

david opp · 7:11 PM
I have had a urologist also recommend oxybutanin for ADT hot flashes

AnCan – rick · 7:11 PM
https://www.nejm.org/doi/full/10.1056/NEJMc1801992?query=TOC&

TonyFig · 7:15 PM
Neck fans are another option.

TonyFig · 7:16 PM
https://www.amazon.com/s?k=neck+fans+that+blow+cold+air&crid=3DRXO7F49TVE5&sprefix=neck+fan%2Caps%2C149&ref=nb_sb_ss_ts-doa-p_2_8

AnCan – rick · 7:24 PM
Here’s the Mayo paper by Brad Stish re. oxybutynin https://www.medpagetoday.com/meetingcoverage/asco/110457?xid=nl_mpt_DHE_2024-06-03&eun=g1169472d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%20Evening%202024-06-03&utm_term=NL_Daily_DHE_dual-gmail-definition&mc_cid=81fa35ee19&mc_eid=838454d636&mc_cid=1550e5c67f&mc_eid=838454d636

AnCan – rick · 7:27 PM
Forget that link – here’s the right one https://www.medpagetoday.com/meetingcoverage/asco/110457?xid=nl_mpt_DHE_2024-06-03&eun=g1169472d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%20Evening%202024-06-03&utm_term=NL_Daily_DHE_dual-gmail-definition&mc_cid=81fa35ee19&mc_eid=838454d636&mc_cid=1550e5c67f&mc_eid=838454d636

AnCan – rick · 7:30 PM
The culprit that makes oxyb. work better with abi is the CYP3A4

Steve Roux, North Michigan · 7:54 PM
I’m late for dinner. GREAT Mtg guys! See you next week!

John A · 8:14 PM
insufficiency fractures: result of normal stress on abnormal bone ….fatigue fx: abnormal stress on normal bone…. .pathological fx: diseased weakened bone due to tumors or abnormal bone . ….stress fx: means chronic mechanical stress exceeds the bone’s capacity

Bob Schwartz, USN, Venice FL · 8:15 PM
Another good mtg., have to go.

dan, alexandria · 8:15 PM
thanks all, have to go…