The TALK is a series of webinars addessing how parents and kids of every age speak to each other about their health conditions. If you haven’t noticed, this is a topic that rarely get aired in public – AnCan hopes to address that over the next several months.
We started last Tuesday, June 30 with a discussion around prostate cancer, moderated by genitourinary medical oncologist extraordinaire, Dr. Alicia Morgans speaking with panel members that included pairs of father and child from ages 17 to 43. We also welcomed Dr. Ryan Berglund, a urologist at Clevaland Clinic and spokesperson for MENtion It, a men’s health awareness campaign sponsored by his institution. Dr. Berglund had excellent slides and a 2 minute video that we were unable to view due to a SNAFU by our co-presenters, UsTOO. But the magic of modern technology allows us to provide them to you here …. click here – the video is embedded in the 5th of 6 slides. And to watch the whole, outstanding presentation, click on the video above
New G4+4 Dx with very low PSA; Tx after Lu177 PSMA fails; immunotherapy with no positive markers vs Jevtana; perineal pain; successful RT to prostate for Mx man; remarkable continued success from abi; interpreting inconsistent scan report; recurrent PCa plateaus w/o treatment; continued success from PARP-I
Chat Log
Jake Hannam (to Everyone): 5:21 PM: Jonathan Epstein 410-955-5043
Len (to Everyone): 6:00 PM: Talabostat is an experimental drug that initiates an inflammatory response in the tumor microenvironment, converting cold tumors to hot tumors and thereby making them better targets for checkpoint inhibitors, like pembro or nivolumab. The open-label Phase 2 basket trial is NCT04171219
scott (to Everyone): 6:01 PM: I have to go. I have an online class tonight. Best to everyone. See you next meeting.
Larry Fish (to Everyone): 6:35 PM: there are a number of variations on the ‘perianal abscess leading to lumps and related painful cysts and common and unusual perianal conditions….you can just Google any of the related terms and get to the articles and links that I ran into in my intermittant condition and still looking for a definitive answer or treatment that relolves it permanently. So I use a ring pillow for my chair and it comes and goes.
Editor’s Pick: Why are there no new chemotherapy treatments for prostate cancer?
Topics Discussed
Using Procrit; docitaxel + carboplatin study; chemotherapy issues; bone density scans; itchy skin; cramping; chemo cycles vs rounds; pre-chemo advice; why no new chemo treatments?;genetic vs somatic gene testing; Covid19 impact on advanced treatment; scanning for recurrence – sensitivity; ROS1 mutation; liquid vs solid Bx analysis; are metastatic PCa cells homogenous; rectal pain post RT
Pick of the Week: Do academic GU med oncs have a clinical trial conflict of interest?
Topics Discussed
Finding a quarterback GU med onc in Pennsylvania; do academic GU med oncs have a trial conflict of interest?; no prednisone with chemo; what mutation drives your PCa; gynecomastia remedies; is too much succes from a 2nd line HT a bad thing?; Dr. Daniel Petrylak @ Yale; how do you follow up your RT/SBRT?; painful Lupron shots; generic abiraterone co-pay assistance
Chat Log
scott (to Everyone): 3:31 PM: could you spell that again…the gumedical oncologist?
Len (to Everyone): 3:31 PM: genitourinary
Len (to Everyone): 3:31 PM: genito-urinary medical oncologist
Peter K : 3:38 PM: Allentown to MSK in Bedminster, NJ is only 1 hour drive. Same distance and time to Philly.
Peter K : 3:52 PM: Roswell Park is not far from Rochester
scott (to Everyone): 3:54 PM: how do you spell and what is something lilke “sabozitaxil” she is referring to? anyone?
Len (to Everyone): 3:55 PM: cabazitaxel
Len (to Everyone): 3:55 PM: It’s a form of chemotherapy very similar to docetaxel
scott (to Everyone): 3:55 PM: how do you spell it? thanks
Len (to Everyone): 3:59 PM: cabazitaxel
Len (to Everyone): 4:00 PM: trade name is Jevtana
scott (to Everyone): 4:03 PM: my big question tonight, if I get to ask, is what is best foundation or group for financial assistance with Zytiga copays?
Len (to Everyone): 4:10 PM: Scott, go here: https://www.janssencarepath.com/patient/zytiga/cost-support
scott (to Everyone): 4:15 PM: Janssen won’t help if you have Medicare
In the context of prostate cancer, newly diagnosed men with low and intermediate disease often consider focal therapy modes such as cryotherapy, HIFU or targeted radiation for intial treatment. And more frequently, we are seeing some of these modes employed for adjuvant and salvage therapy.
AnCan’s good friend, John Fortin, just published a short report on UroToday summarizing the findings from a Febraury 2020 Conference that considered focal therapy. This may well be of interest to other cancers, like ovarian and breast, where focal modes are also employed. John’s report linked above does not address follow-up treatment in the case of recurrent disease after intial treatment.
