Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

AnCan is closing out its Annual Fundraising Campaign. If you haven’t donated yet, consider the priceless value we bring . Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Denovo metastatic BRCA2 Newbie stumps us all!

Topics Discussed

High volume denovo Mx Gent with BRCA germline can’t fiing a treatment that controls his T or his PSA; starting IMRT along with constipation; 2nd docetaxel easier with less fatigue than the first; liver returning to normal after 6x docetaxel; so back to full daro dose; T returns within 3 months of stopping 12 mo of orgovyx; BCBS turns down Prolia for -2.7 osteoprosis – did doc ask for wrong denosumab; ‘ciiling cap’ discussion; opting for new Plan Ds (drugs); Inherited Mutations discussed;

Chat
  • Alfredo in Houston, TX sent: 4:24 PM

  • Larry (Alaska) sent: 4:50 PM

    should we test for LH and FSH levels?

  • Alfredo in Houston, TX sent: 4:51 PM

    Dr. Jack, would an LH level be helpful in this case?

  •  Jeff Marchi – San Francisco sent: 4:52 PM

    small cell= neuroendocrine (not exactly: rd)

  • AnCan–John A sent: 4:55 PM

    advanceduropathology.com 5162807930 Dr Epstein prostate pathology expert

  • Alfredo in Houston, TX sent: 5:00 PM

    the relatively long half-life of injectable testosterone undecanoate means its effects can last for weeks, but probably not months

  • Jeff Marchi – San Francisco sent: 5:08 PM

    has anyone had VMAT radiation?

  • Gary Martin sent: 5:09 PM

    I had that prostate inflammation first and second round docetaxel. my oncologist did not know cause. Suggested UTI, which have the same symptom I had in round 1 and 2. I figured it was chemo working on prostate.

  • Julian – Houston sent: 5:13 PM

    Jeff, I have had VMAT radiation.

  • Jeff Marchi – San Francisco sent: 5:13 PM

    how well did it work? any side effects?

  • Jack sent: 5:14 PM

    Enzalutamide blocks androgen binding which disrupts the negative feedback loop that normally supresses testosterone this leads to compensatory increases in LH and subsequent increases in testosterone

  • Julian – Houston sent: 5:14 PM

    It worked quite well – I have been in remission for over 5 years. I am now having some radiation effects but not severe

  • AnCan – rick sent: 5:18 PM

  • Bruce Schrimpf sent: 5:20 PM

    I have not met or heard of him.

  • Gary Martin sent: 5:32 PM

    I had insurance denial of Prolia (bone strengthening)- anyone encounter denial of Prolia?

  • Julian – Houston sent: 5:34 PM

    Aetna no longer approves Prolia.

  • Larry (Alaska) sent: 5:36 PM

    Bone loss is largely drivenby estradiol deficiency (just as it is in post-menopausal women). Testosterone deprivation also lowers a man’snatural estradiol. A low-dose estradiol suppement can avoid the need for bune-building agents. Agents which are expensive and bring their own set of adverese side effects.

  • Larry (Alaska) sent: 5:43 PM

    Calcium + Magnesium:

    AI Says: Why Separation Helps Competition for Absorption: High levels of calcium can block magnesium absorption in the intestines, and vice-versa. Optimizing Intake: Spacing them out (2-4 hours apart is a common suggestion) minimizes this competition, allowing your body to absorb each mineral more effectively. When It’s Okay to Take Them Together Multivitamins: If they are in smaller, balanced amounts within a multivitamin, the interaction is usually not an issue. With Food: Taking them with food can also help with absorption and reduce digestive upset.

  • RJ Smith (Seattle) sent: 5:47 PM

    Cold Cap system is https://paxmanscalpcooling.com/

  • Julian – Houston sent: 5:52 PM

    Volumetric-modulated Arc Therapy (VMAT)

  • Alfredo in Houston, TX sent: 5:55 PM

    Well, here is a longish article, but it does seem to describe the difference between IMRT and VMAT, https://en.wikipedia.org/wiki/Radiation_therapy

  • Julian – Houston sent: 5:57 PM

  • Alfredo in Houston, TX sent: 5:58 PM

    I have to leave now, sending everyone good wishes for the new year. Good night! and thank you!

  • Alan Swope sent: 5:59 PM

    Thanks all. I have to leave. Good information.

  • Don Rogers sent: 5:59 PM

    look at Scriptco.com for generic drugs. Huge saving even with the $140 yearly fee.

  • Bruce Schrimpf sent: 6:01 PM

    Thanks for the good discussion!

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/5/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/5/26

HAPPY NEW YEAR to all AnCan’s YouTube viewers.    AnCan is closing out its Annual Fundraising Campaign. If you haven’t donated yet, consider the priceless value we bring . Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

 

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

HEADSUP – another long session!

Editor’s Pick: Like London buses, topics come in clusters this week – post-surgery recurrence, and monotherapy daro

Topics Discussed

Recurrence 3+ months post-surgery is confusing given medical reports; sitting on hands post 2017 RRP has dire cinsequences; more rapid recurrence requires PSMA scan for younger Gent; low T post treatment raises question whether to force it castrate; oxybutinin manages hot sweats… ARSI makes no difference; Gent considers going from doublet to mono; recently diagnosed denovo Mx man learns he’s 5+4; should he keep one Pluvicto session in reserve?; get a DEXA scan before starting bone stregthener; can a layman read their PSMA scan?; is he ready for mono daro?; should a FAP (Fibroblast Activation Protein Inhibitor) scan be considered?; PSMA needed as PSA rises post IHT; connections between prostate and thyroid cancer; Gent resumes doublet but doesn’t watch PSA – more concerned with duration?!?

Chat
  •  Jim Stewart Reno, NV sent: 7:24 PM

    Family commitment have to sign off…Happy New Year everyone

  • Jim Marshall, Veteran, Alexandria, VA sent: 7:36 PM

    My solution for HOT FLASHES at night has been is even if the room is 55, I have a 12″ fan blowing directly on my face. This is done year round.

  • Paul Schomer sent: 7:50 PM

    I am not, no, Jim

  • RJ Smith (Seattle) sent: 7:50 PM

    NTD–will update next week on how Chemo#3 goes (docetaxel infusion tomorrow, fingers crossed).

  • Thomas Matica sent: 8:07 PM

    Leaving the meeting. Thanks to everyone. Happy New Year.

  • Jim Marshall, Veteran, Alexandria, VA sent: 8:11 PM

    Eric – When you are fatigued, go out and exericse despite the body telling you NOT!!!!

  • S. Datta sent: 8:14 PM

    FAPI (Fibroblast Activation Protein Inhibitor)

  • Larry Schuller – Alaska sent: 8:18 PM

    It is not crazy to want your testosterone back. Intermittent ADT can do that and it is showing promise as a tactic. Bipolar ADT (BAT) is a little crazier, but has some promise also. If you want to go wild, check out Dr Robert Gatenby’s work at Moffit in Florida. Intersesting stuff there.

  • John G. sent: 8:19 PM

  • AnCan – rick sent: 8:20 PM

  • Jeffrey Green sent: 8:23 PM

    Jay Mills Chatanooga- Though I didn’t follow the whole conversation, I heard you say something to the effect of, “I may have mets all over the place, in addition to what shows on PSMA.”

  • Barry Blomquist sent: 8:28 PM

    Have to jump – thanks everyone. Happy New Year

  • Eric Curtis sent: 8:30 PM

    Thanks all – gotta go

  • Jeffrey Green sent: 8:31 PM

    Got to start winding down here. Thanks for all you guys. See you next time.

  • Len sent: 8:34 PM

    Source is AI: Bidirectional Risk: Men diagnosed with thyroid cancer have a roughly 28% to 30% higher risk of later being diagnosed with prostate cancer compared to the general population. Conversely, men with prostate cancer are more likely to be diagnosed with thyroid cancer.

  • Robert sent: 8:35 PM

    Thanks Len. I read the same thing.

  • dan-s sent: 8:49 PM

    Thanks all… another good session. Have to sign off for the evening. Happy New Year…

  • Jay T in MN sent: 8:50 PM

    My hospital was charging the insurance company about $20,000.

  • gary peters sent: 8:50 PM

    I did not know this about thyroid C and PC. Thank you.

  • Jon McPhee Toronto sent: 8:50 PM

    Do a PSA test once a month. Cheap. PSMA/PET is expensive and harder to get.

  • Jay T in MN sent: 8:51 PM

    I “only” had to pay $1000 for my portion of PET PMSA

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

AnCan is in its Annual Fundraising Campaign. Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

HEADSUP – long session

Editor’s Pick: AFib may dictate use of ARSI – 2nd line anti-androgen

Topics Discussed

Dublin EI Newbie needs a GU MO; … and so does 85 yr old from Eau Claire, WI who’s Mayo doc has lost the way; roller coaster metastatic Gent starting with Kishan at UCLA; almost through RT, and finds germline CHEK2; doing well and very thankful to AnCan; germline BRCA2 man not gettiing SoC in Mississippi; great chemo results – now explore debulking; should a man with Afib be on abiraterone?; waiting for PSMA scan after 3x Pluvicto; fatigue & brain fog from abi doublet; avoid 6-month depot LHRH; Dr. Szmulewicz recommends debulking; Florida vacay interferes with treatment plan; 2nd opinion on Bx required; SBRT vs IMRT for man with urinary issues

Chat
  • AnCan – rick sent: 4:35 PM

    Silke Gillesen

  • AnCan – rick  sent: 4:55 PM

  • AnCan – rick sent: 4:58 PM

  • Len sent: 5:05 PM

    Don Larsen should be on a bone strengthener, if not already on one.

  • Jay in MN sent: 5:12 PM

    Sounds like it!

  • AnCan – rick sent: 5:55 PM

  • AnCan – rick sent: 5:59 PM

  • Jon McPhee Toronto sent: 6:07 PM

    Gotta go. Catch up next year. Merry Christmas and Happy New Year to everyone.

  • Alan M – New Jersey sent: 6:09 PM

    Happy Holidays to all. Good night.

  • Steven Waite sent: 6:16 PM

    Got to run. Thank you all very much. Happy Holidays one and all.

  • Barry Blomquist sent: 6:30 PM

    Have to jump, Merry Christmas Everyone!

  •  AnCan – rick sent: 6:32 PM

    switch from abi from to daro

  • gary peters sent: 6:35 PM

    Same from me, gents.

  • Eric Curtis sent: 6:36 PM

    Great to see everyone. Happy Holidays to all.

  • Bob Alvord sent: 6:39 PM

    Gotta run. A very Merry Christmas and Happy New Year to everyone.

  • Dan – Schenectady, NY sent: 6:40 PM

    Merry Christmas all.

  • AnCan – rick sent: 6:47 PM

    Ep-stine! Dr. Jonathan Epstein – https://advanceduropathology.com/ Tel: 516-760-2037 jepstein@imppllc.com

  • AnCan – rick sent: 6:47 PM

    Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881

  • Jeff Marchi – San Francisco sent: 6:49 PM

    Gotta run. Merry Christmas and happy new year to all.

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 15, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 15, 2025

AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Finishing 10x Pluvicto; and, following up post-surgery for BRCA germline Gent

Topics Discussed

Endorsing AnCan; 10 rounds of Pluvicto – with a break after 6; low dose estrigen enquiry; Newbie want to know when to intervene on recrrence post-surgery; Tempus report shows PTEN and more; cribriform favors radiation over surgery; time for another PSMA scan; IHT or mono daro – beware of gynecomastia; can reduciing daro dose loer fatigue?; more on cribriform and RT; debulking primary tumor post chemo; BRCA germline Gent wondes when to intervene with RT post RP – and if to include HT

Chat
  • Jeff Marchi – San Francisco

    sent: 6:12 PM

    friday this week

  • Thomas Matica

    sent: 6:14 PM

    Glad to hear Peter Kafka is doing well.

  • Stan Friedman

    sent: 6:29 PM

    after 5 sessions, my psa is now undetectable

  • Mark N

    sent: 6:30 PM

    What is the drug that was just discussed?

  • Larry Schuller – Alaska

    sent: 6:31 PM

    Mark, Pluvicto work the same way imaging for PSMA-PET scans do. Instead of just giving an image of where the cancer is, it delivers a higher dose that is therapeutic

  • Mark N

    sent: 6:31 PM

    Thanks!

  • AnCan–John A

    sent: 6:33 PM

    Lee–still undetectable psa?

  • Larry Schuller – Alaska

    sent: 6:34 PM

    Many side effecs of standard ADT is actually caused by estradiol deficiency (which is caused by the absence of testosterone). This deficiency is the same as what causes osteopoosis in post-menopausal women.

  • Larry Schuller – Alaska

    sent: 6:35 PM

    Men normally have between 15 and 50 levels of estradiol

  • Larry Schuller – Alaska

    sent: 6:36 PM

    Breast growth and nipple sensitivity is a side effect of standard ADT too, but at a lower incidence than with estradiol.

    Jerry G, Brighton, MI

    sent: 6:39 PM

    I’ll add support for higher dose estradiol, for me in the absence of testosterone. My osteopenia cleared up, and I am now in the normal range for bone density. I have been on permanent ADT for almost 7 years now, and estradiol for just over 6. My PSA is still undetectable

    Larry Schuller – Alaska

    sent: 6:49 PM

    Tom Miller’s Lymph nodes?

  • Lee Baylin, Baltimore

    sent: 6:52 PM

    Dr. John, I’m still undectable.

  • AnCan – rick

    sent: 6:59 PM

    Curtis DeVille an Channing Paller at Sibley

  • Bob Schwartz U.S.N. Venice, FL.

    sent: 7:00 PM

    Once again, many thanks to the Unknown Anonymous Benefactor, who is matching donations to AnCan. Please know that your kindness is very much appreciated. Good meeting as usual, unfortunately have to go early.

  • Larry Schuller – Alaska

    sent: 7:08 PM

    A promising area of research, though

  • Larry Schuller – Alaska

    sent: 7:09 PM

    Immunotherapy is a promising area of research.

  • Larry Schuller – Alaska

    sent: 7:09 PM

    Immunotherapy is a promising area of research

  • Larry Schuller – Alaska

    sent: 7:09 PM

    Oops. Sorry about the triple post

  • Eric James; Tyler TX

    sent: 7:12 PM

    Genetic Variant Results ALK – p.G5R – c.13G>A Missense variant Assessment:Detected CDKN2A – CDKN2A Copy number loss Assessment:Detected CDKN2B – CDKN2B Copy number loss Assessment:Detected MTAP – MTAP Copy number loss Assessment:Detected PIK3CA – p.E545K – c.1633G>A Missense variant (exon 9) – GOF Assessment:Detected PTEN – p.A34fs – c.101del Frameshift – LOF Assessment:Detected TMPRSS2::ERG Fusion – TMPRSS2 – ERG Chromosomal rearrangement Assessment:Detected

  • RJ Smith (Seattle)

    sent: 7:12 PM

    SYNC-T? https://syncromune.com/science/

  • Darren Chervitz

    sent: 7:17 PM

    Gedatolisib is a PI3K/AKT/mTOR (PAM) pathway inhibitor showing promising early results in clinical trials for metastatic castration-resistant prostate cancer (mCRPC), often combined with AR inhibitors like darolutamide, targeting the PI3K pathway which is frequently altered in advanced prostate cancers, especially with PTEN loss, to control cell growth and survival, with studies aiming to find optimal doses and demonstrate improved survival and response rates.

  • Larry Schuller – Alaska

    sent: 7:26 PM

    Get a baseline bone density, too

  • Larry Schuller – Alaska

    sent: 7:29 PM

    Exercise program. A healthy body withstands the rigors of treatment better

  • RJ Smith (Seattle)

    sent: 7:30 PM

    Along with all the other tests, PROSTOX might help to know if you are prone to long-term side effects from the radiation. Most people aren’t. Like Rick said, though, if you’ve decided on radiation–might just take go for it. 😉

  • Steve L

    sent: 7:44 PM

    By the way, My immunotherapy induced Pulmonary embolism cleared this summer after about 12 months. I started feeling better immediately. They have pulled me off Eliquis. I am back to scuba diving. Currently feeling very good.

  • AnCan–John A

    sent: 7:46 PM

    Noted, Steve. that’s good

  • Bruce Schrimpf

    sent: 7:55 PM

    Again A very good discussion! Should I not see you before, Merry Christmas!

  • AnCan – rick

    sent: 8:00 PM

    https://jamanetwork.com/journals/jamaoncology/article-abstract/2840006?guestAccessKey=a83645e8-deae-423a-9139-d772a3301482&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jamaoncology&utm_content=olf-recommended-tfl_&utm_term=110625

  • Larry Schuller – Alaska

    sent: 8:15 PM

    Re: Second reads on PSMA-PET scan. I had a scan at Fred Hutch Cancer Center and the report was MUCH MORE detailed than the scan I had at my local imaging center. So, Second reads on the original scan imaging is valuable, in my opinion.

  • Larry Schuller – Alaska

    sent: 8:17 PM

    On top of that, the written report is only words. Actually showing the imaging to my surgeon saved me an extra surgery. Not mentioned on the report’s text wat that a reservoir from a prior surgery would complicate a robotic prostatectomy. It turns out that if a robotic had been started, it would have had to have been aborted, necessitating a subsequent open procedure.

  • Larry Schuller – Alaska

    sent: 8:18 PM

    Show your original imaging to your doctors, especially if approaching surgery

  • dan-s

    sent: 8:21 PM

    Thanks all for another great mtg – I have to leave (up early tomorrow)

  • AnCan – rick

    sent: 8:22 PM

    Gents – long posts in the Chat poses a problem when we write up these meetings. There is a limit in You Tube on what we can paste.

Hi-Risk/Recurrent/Advanced PrCa Video Chat, 1/13/26

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 25, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 25, 2025

Happy Thanksgiving to all our AnCan particpants, especially if not on our mailing list. We’d have to ask why not, when you can sign up at https://ancan.org/contact-us/ and recive our great Newsletter/Reminder.

CORRECTION (rd)

I want to apologize and make a correction for someting I said in last Tuesday’s support group. At the end we were discussing adding a couple of Pluvicto treatments to Metastatic Directed Therapy. However this was for a man who had progressed rather than having just been diagnosed oligometastatic as in the LUNAR trial reported in the Reminder last week. I mentioned he might be eligible in the USA as Pluvicto is approved for metastatic hormone sensitive  prostate cancer. This is not the case, and I misspoke. PSMAddtion was positively reported for mHSPC use at the recent ESMO conference – thank you Dr. Paul for this link. To date, it has not been FDA approved. I knew of the trial and got ahead of the game; although I was confusing it with PSMAFore.

 

AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Robust discussion around testoterone early on – and thoughts about combining therapies at the end.

Topics Discussed

how long to stay on HT leads to rich discussion on testosterone; did salvage cryo bring his PSA down? And he needs a GU MO QB; cupplementing T with Clomid is new to AnCan; casting around for intial treatment; ststarting Prolia that’s NO lifetime drug; tachycardia and AFib; recovering from 6x dicetaxel; b est treatment options for Stage T3 ; holding steady; allowing PSA to rise to find source of oligo-Mx; can we add Pluvicto to MDT later in the cycle?

Chat
  • Frank Ciambra sent: 5:10 PM

    my wife is a nurse working in cardiology ,im going to share this witth her

  • John M – Chicago sent: 5:11 PM

    Don I am doing great. Feeling stronger. Exercise is the KEY. Everything progressing according to plan. I’m going to my sons house to be with him, his wife and my grandson. What about you?

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:27 PM

    AFib – Join the club with others. Jim Marshall

  • Julian – Houston sent: 5:29 PM

    I had AFIB then had cardiac ablation in March 25 and then it went away!

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:30 PM

    AFib is Mutually exclusive with Vitamin K. Jim Marshall;

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:32 PM

    Have AFib and take Blood Thinner, Pradaxa, Metropolol Tartrate and a Statin – Pravastatin. Jim Marshall

  • AnCan – rick sent: 5:33 PM

    abir-A-terone

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:34 PM

    Lupron/Eligard and Abi have warnings for those who have heart issues. Jim Marshall

  • Alfredo in Houston, TX sent: 5:37 PM

    Vitamin K potentially interferes with anticoagulants (blood thinners). And you also get vitamin K in your diet from leafy greens. Everyone please remember to discuss ALL supplements with your physician AND pharmacist.

  • TonyFig sent: 5:39 PM

    There is a strong link between sleep apnea bringing on A-Fib.

  • Alfredo in Houston, TX sent: 5:41 PM

    I am being called to supper now, so I must leave — but not before wishing a Happy Thanksgiving to everyone. Good night

  • AnCan–John A sent: 5:48 PM

    stereotactic body radiation therapy

  • Julian – Houston sent: 5:53 PM

    Happy Thanksgiving to all!!!

  • TonyFig sent: 5:56 PM

    Blood Thinner – a naturopath approach for anticoagulation can be quite risky as it may not present consistent and reliable levels to address A-Fib episodes or other cardiac issues. I discussed this with cardiac surgeons as well as a heart biologic replacement valve supplier. I would not take the risk of naturopath solution for this application.

    Nattokanese, Vit E, Ginger, Omega Oils in high dose, Cayene Pepper Tumeric, etc

  • John M – Chicago sent: 6:04 PM

    Have a great Thanksgiving everyone!

  • Dennis Correia sent: 6:07 PM

    Happy Thanksgiving all

  • Barry Blomquist sent: 6:07 PM

    Have to jump – Happy Thanksgiving to everyone and thank you all!

  • dan-s sent: 6:09 PM

    Thanks all – Happy Thanksgiving

  • Jerry Pelfrey sent: 6:10 PM

    Time to go. Everyone have a wonderful Thanksgiving.

  • Larry (Alaska) sent: 6:14 PM

    Suggesting Pluvicto as first-line treatment instead of ADT as first-line?

  • Bob Y — Los Angeles sent: 6:15 PM

    Thank you, all, for your good counsel.

  • David Muslin sent: 6:17 PM

    Gobble Gobble love you guys