Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

AnCan is in its Annual Fundraising Campaign. Please donate – especially if you watch our recordings and are not on our Mailchimp list. https://ancan.org/donate/

Hear Founder, rick davis talk about how AnCan came to be in this 20-min podcast dropped this week on Empowered Patient Radio http://empoweredpatientradio.com/virtual-support-groups-remove-barriers-encourage-sharing-honest-experiences-to-fight-misinformation-with-rick-davis-ancan

AnCan thanks the following sponsors for making this recording possible: Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

HEADSUP – long session

Editor’s Pick: AFib may dictate use of ARSI – 2nd line anti-androgen

Topics Discussed

Dublin EI Newbie needs a GU MO; … and so does 85 yr old from Eau Claire, WI who’s Mayo doc has lost the way; roller coaster metastatic Gent starting with Kishan at UCLA; almost through RT, and finds germline CHEK2; doing well and very thankful to AnCan; germline BRCA2 man not gettiing SoC in Mississippi; great chemo results – now explore debulking; should a man with Afib be on abiraterone?; waiting for PSMA scan after 3x Pluvicto; fatigue & brain fog from abi doublet; avoid 6-month depot LHRH; Dr. Szmulewicz recommends debulking; Florida vacay interferes with treatment plan; 2nd opinion on Bx required; SBRT vs IMRT for man with urinary issues

Chat
  • AnCan – rick sent: 4:35 PM

    Silke Gillesen

  • AnCan – rick  sent: 4:55 PM

  • AnCan – rick sent: 4:58 PM

  • Len sent: 5:05 PM

    Don Larsen should be on a bone strengthener, if not already on one.

  • Jay in MN sent: 5:12 PM

    Sounds like it!

  • AnCan – rick sent: 5:55 PM

  • AnCan – rick sent: 5:59 PM

  • Jon McPhee Toronto sent: 6:07 PM

    Gotta go. Catch up next year. Merry Christmas and Happy New Year to everyone.

  • Alan M – New Jersey sent: 6:09 PM

    Happy Holidays to all. Good night.

  • Steven Waite sent: 6:16 PM

    Got to run. Thank you all very much. Happy Holidays one and all.

  • Barry Blomquist sent: 6:30 PM

    Have to jump, Merry Christmas Everyone!

  •  AnCan – rick sent: 6:32 PM

    switch from abi from to daro

  • gary peters sent: 6:35 PM

    Same from me, gents.

  • Eric Curtis sent: 6:36 PM

    Great to see everyone. Happy Holidays to all.

  • Bob Alvord sent: 6:39 PM

    Gotta run. A very Merry Christmas and Happy New Year to everyone.

  • Dan – Schenectady, NY sent: 6:40 PM

    Merry Christmas all.

  • AnCan – rick sent: 6:47 PM

    Ep-stine! Dr. Jonathan Epstein – https://advanceduropathology.com/ Tel: 516-760-2037 jepstein@imppllc.com

  • AnCan – rick sent: 6:47 PM

    Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881

  • Jeff Marchi – San Francisco sent: 6:49 PM

    Gotta run. Merry Christmas and happy new year to all.

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 15, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 15, 2025

AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Finishing 10x Pluvicto; and, following up post-surgery for BRCA germline Gent

Topics Discussed

Endorsing AnCan; 10 rounds of Pluvicto – with a break after 6; low dose estrigen enquiry; Newbie want to know when to intervene on recrrence post-surgery; Tempus report shows PTEN and more; cribriform favors radiation over surgery; time for another PSMA scan; IHT or mono daro – beware of gynecomastia; can reduciing daro dose loer fatigue?; more on cribriform and RT; debulking primary tumor post chemo; BRCA germline Gent wondes when to intervene with RT post RP – and if to include HT

Chat
  • Jeff Marchi – San Francisco

    sent: 6:12 PM

    friday this week

  • Thomas Matica

    sent: 6:14 PM

    Glad to hear Peter Kafka is doing well.

  • Stan Friedman

    sent: 6:29 PM

    after 5 sessions, my psa is now undetectable

  • Mark N

    sent: 6:30 PM

    What is the drug that was just discussed?

  • Larry Schuller – Alaska

    sent: 6:31 PM

    Mark, Pluvicto work the same way imaging for PSMA-PET scans do. Instead of just giving an image of where the cancer is, it delivers a higher dose that is therapeutic

  • Mark N

    sent: 6:31 PM

    Thanks!

  • AnCan–John A

    sent: 6:33 PM

    Lee–still undetectable psa?

  • Larry Schuller – Alaska

    sent: 6:34 PM

    Many side effecs of standard ADT is actually caused by estradiol deficiency (which is caused by the absence of testosterone). This deficiency is the same as what causes osteopoosis in post-menopausal women.

  • Larry Schuller – Alaska

    sent: 6:35 PM

    Men normally have between 15 and 50 levels of estradiol

  • Larry Schuller – Alaska

    sent: 6:36 PM

    Breast growth and nipple sensitivity is a side effect of standard ADT too, but at a lower incidence than with estradiol.

    Jerry G, Brighton, MI

    sent: 6:39 PM

    I’ll add support for higher dose estradiol, for me in the absence of testosterone. My osteopenia cleared up, and I am now in the normal range for bone density. I have been on permanent ADT for almost 7 years now, and estradiol for just over 6. My PSA is still undetectable

    Larry Schuller – Alaska

    sent: 6:49 PM

    Tom Miller’s Lymph nodes?

  • Lee Baylin, Baltimore

    sent: 6:52 PM

    Dr. John, I’m still undectable.

  • AnCan – rick

    sent: 6:59 PM

    Curtis DeVille an Channing Paller at Sibley

  • Bob Schwartz U.S.N. Venice, FL.

    sent: 7:00 PM

    Once again, many thanks to the Unknown Anonymous Benefactor, who is matching donations to AnCan. Please know that your kindness is very much appreciated. Good meeting as usual, unfortunately have to go early.

  • Larry Schuller – Alaska

    sent: 7:08 PM

    A promising area of research, though

  • Larry Schuller – Alaska

    sent: 7:09 PM

    Immunotherapy is a promising area of research.

  • Larry Schuller – Alaska

    sent: 7:09 PM

    Immunotherapy is a promising area of research

  • Larry Schuller – Alaska

    sent: 7:09 PM

    Oops. Sorry about the triple post

  • Eric James; Tyler TX

    sent: 7:12 PM

    Genetic Variant Results ALK – p.G5R – c.13G>A Missense variant Assessment:Detected CDKN2A – CDKN2A Copy number loss Assessment:Detected CDKN2B – CDKN2B Copy number loss Assessment:Detected MTAP – MTAP Copy number loss Assessment:Detected PIK3CA – p.E545K – c.1633G>A Missense variant (exon 9) – GOF Assessment:Detected PTEN – p.A34fs – c.101del Frameshift – LOF Assessment:Detected TMPRSS2::ERG Fusion – TMPRSS2 – ERG Chromosomal rearrangement Assessment:Detected

  • RJ Smith (Seattle)

    sent: 7:12 PM

    SYNC-T? https://syncromune.com/science/

  • Darren Chervitz

    sent: 7:17 PM

    Gedatolisib is a PI3K/AKT/mTOR (PAM) pathway inhibitor showing promising early results in clinical trials for metastatic castration-resistant prostate cancer (mCRPC), often combined with AR inhibitors like darolutamide, targeting the PI3K pathway which is frequently altered in advanced prostate cancers, especially with PTEN loss, to control cell growth and survival, with studies aiming to find optimal doses and demonstrate improved survival and response rates.

  • Larry Schuller – Alaska

    sent: 7:26 PM

    Get a baseline bone density, too

  • Larry Schuller – Alaska

    sent: 7:29 PM

    Exercise program. A healthy body withstands the rigors of treatment better

  • RJ Smith (Seattle)

    sent: 7:30 PM

    Along with all the other tests, PROSTOX might help to know if you are prone to long-term side effects from the radiation. Most people aren’t. Like Rick said, though, if you’ve decided on radiation–might just take go for it. 😉

  • Steve L

    sent: 7:44 PM

    By the way, My immunotherapy induced Pulmonary embolism cleared this summer after about 12 months. I started feeling better immediately. They have pulled me off Eliquis. I am back to scuba diving. Currently feeling very good.

  • AnCan–John A

    sent: 7:46 PM

    Noted, Steve. that’s good

  • Bruce Schrimpf

    sent: 7:55 PM

    Again A very good discussion! Should I not see you before, Merry Christmas!

  • AnCan – rick

    sent: 8:00 PM

    https://jamanetwork.com/journals/jamaoncology/article-abstract/2840006?guestAccessKey=a83645e8-deae-423a-9139-d772a3301482&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jamaoncology&utm_content=olf-recommended-tfl_&utm_term=110625

  • Larry Schuller – Alaska

    sent: 8:15 PM

    Re: Second reads on PSMA-PET scan. I had a scan at Fred Hutch Cancer Center and the report was MUCH MORE detailed than the scan I had at my local imaging center. So, Second reads on the original scan imaging is valuable, in my opinion.

  • Larry Schuller – Alaska

    sent: 8:17 PM

    On top of that, the written report is only words. Actually showing the imaging to my surgeon saved me an extra surgery. Not mentioned on the report’s text wat that a reservoir from a prior surgery would complicate a robotic prostatectomy. It turns out that if a robotic had been started, it would have had to have been aborted, necessitating a subsequent open procedure.

  • Larry Schuller – Alaska

    sent: 8:18 PM

    Show your original imaging to your doctors, especially if approaching surgery

  • dan-s

    sent: 8:21 PM

    Thanks all for another great mtg – I have to leave (up early tomorrow)

  • AnCan – rick

    sent: 8:22 PM

    Gents – long posts in the Chat poses a problem when we write up these meetings. There is a limit in You Tube on what we can paste.

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 9, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 9, 2025

AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Lotsa confusion throughout this week! To pick just one, Signatera MRD test.

Topics Discussed

Newbie has a great HCP team – but seeking more; Mayo bamboozles this Newbie – needs more and reliable information; another Newbie chose to leave himself on ADT for 5 years – and wonders about fatigue and weight gain he’s now shed w. GLP; muscle mass with low T; Regular finds Signatera MRD test – but it’s not yet FDA approved for prostate cancer… & Dr. Jack’s been following this test a long time; Epstein downgrades Gent from 4+5 to 4+3 – Kishan & MR Linac next; elevated liver enzymes after chemo; steady as he goes with 0.03 rise; what’s pituitary’s role for testosterone; PSA testing during Pluvicto

Chat
  • Alexander Lalov, Pendleton, IN

    sent: 4:13 PM

    Is the recording going to be made public?

  • Eric James; Tyler TX

    sent: 4:13 PM

    yes, on Youtube

  • AnCan – rick

    sent: 4:14 PM

    All our Recordings are posted on YuTube – over 700

  • Larry (Veteran, Alaskan)

    sent: 4:16 PM

    Check your camera shutter at the top of your screen

  • AnCan – rick

    sent: 4:19 PM

    877 582 7011 GoTo

  • Jeff Marchi – San Francisco

    sent: 4:28 PM

    free genetic testing PROMISE PCa Germline Project

  • AnCan – rick

    sent: 4:31 PM

    Tx Jeff – Doug has germline already

  • Jeff Marchi – San Francisco

    sent: 4:32 PM

    ok i hear you

  • Alexander Lalov, Pendleton, IN

    sent: 4:34 PM

    As far as I know PROMISE do Hereditary Cancer Test Only.

  • AnCan – rick

    sent: 4:35 PM

    Yes Promise is only germline

  • AnCan – rick

    sent: 4:35 PM

    Gents – I have poor bandwidth today . There’s an interent issue here.

  • AnCan – rick

    sent: 4:47 PM

  • Jim Marshall, Veteran, Alexandria, VA

    sent: 4:59 PM

    When you ask for the Promise test, do not specify any doctor. It is between you and Promise. Jim

  • Jay in MN

    sent: 5:10 PM

    👍

  • AnCan – rick

    sent: 5:15 PM

    Dr. Jonathan Epstein – https://advanceduropathology.com/ Tel: 516-760-2037 jepstein@imppllc.com

  • AnCan – rick

    sent: 5:16 PM

    Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881

    Jay – those are the 2 pathologists for a 2nd opinion.

  • Alexander Lalov, Pendleton, IN

    sent: 5:27 PM

    Bary, would you post the web address, please

  • Alexander Lalov, Pendleton, IN

    sent: 5:28 PM

    Oh, Withing is the name. Thnx!

  • John G.

    sent: 5:28 PM

    https://www.youtube.com/watch?v=Ado6dItMebE Yes, even on androgen deprivation therapy (ADT) with testosterone suppressed to near-zero (castration levels), you can increase muscle mass and strength through resistance training, though gains are typically modest and focused on counteracting atrophy rather than dramatic hypertrophy.[1][3] ## Evidence from Studies Multiple clinical trials show prostate cancer patients on ADT gaining muscle mass and fiber size after 12–20 weeks of supervised resistance training, including compound lifts like squats and presses, performed 2–3 times weekly. Progressive overload—gradually increasing weights—prevents fiber size decline in both type I and II muscles and boosts capillarization for better performance. These adaptations occur via mechanical loading and protein synthesis pathways independent of testosterone, such as IGF-1 signaling.

  • Larry (Veteran, Alaskan)

    sent: 5:28 PM

    YMCA “Livestrong” program is designed for cancer survivors. Look it up

  • Larry (Veteran, Alaskan)

    sent: 5:29 PM

    Government funded, so it is free and includes YMCA membership for the 12 week duration,

  • AnCan – rick

    sent: 5:29 PM

  • Eric James; Tyler TX

    sent: 5:30 PM

    Yes, muscle mass may be increased, if you haven’t already been doing resistance training.

  • Larry (Veteran, Alaskan)

    sent: 5:32 PM

    Lupron has been demonstrated to cause weight gain. I am not sure about lymphedema, though.

  • Larry (Veteran, Alaskan)

    sent: 5:33 PM

    Ask about going on an ADT “Vacation”. Stop the ADT and closely observe the PSA response.

  • AnCan – rick

    sent: 5:34 PM

    rick rd@ancan.org dr. john dr.john@ancan.org

  • Larry (Veteran, Alaskan)

    sent: 5:34 PM

    If you go on ADT vacation, do it with the supervision of your oncologist.

  • AnCan – rick

    sent: 5:35 PM

    Larry – he needs to find a new oncologist

  • Eric James; Tyler TX

    sent: 5:49 PM

    Did Dr. Epstein provide any other details? % 4 vs %3? Invasion, intraductal, etc.?

  • AnCan – rick

    sent: 5:56 PM

  • AnCan – rick

    sent: 5:58 PM

    RT machine is MR-Linac

  • Steve Roux, North Michigan

    sent: 6:07 PM

    sorry guys – I need to bug out.

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Mon. Dec 1, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 1, 2025

AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: How do you pick a doctor for a second opinion?

Topics Discussed

bladder control during salvage RT sessions; surgery vs RT for Gent with IDC-P; who to trust for a 2n opinion; gratitude for AnCan’s support; embarking on chemo on ice – report after 1st round;… abd finishing chemo – what next?: recurrence after salvage RT 7 yrs calls for PSMA – but KP is slow on the uptake; T level falls in hours after starrting Orgovyx… really??

Chat
  • AnCan – rick

    sent: 6:03 PM

    877 582 7011

  • AnCan – rick

    sent: 6:05 PM

    Number for GoTo technical support

  • Bob Y — Los Angeles

    sent: 6:21 PM

    Gerry, How did you decide on surgery as the first line of treatment?

  • Jeff Marchi – San Francisco

    sent: 6:27 PM

    wiesner clamp

  • AnCan–John A

    sent: 6:40 PM

    MSKCC nomogram

  • AnCan – rick

    sent: 6:40 PM

    http://nomograms.mskcc.org/Prostate/index.aspx

  • Gerry & Cynthia

    sent: 6:41 PM

    thank you

  • AnCan–John A

    sent: 6:44 PM

    I see PSA, gleason, age, NCCN risk, and tumor stage on the arterra report

  • AnCan–John A

    sent: 6:45 PM

    and the bx slides of course

  • AnCan – rick

    sent: 6:51 PM

    Partin tables

  • Mark N

    sent: 6:52 PM

    Labcorp test 481220

  • TonyFig

    sent: 6:53 PM

    here is another similar labcorp test https://www.labcorp.com/tests/483555/vistaseq-prostate-panel

  • AnCan–John A

    sent: 6:56 PM

    If your focus is on inherited genetic risk factors, the Color gene test is likely more complete. If you are seeking tumor-specific genetic profiling or somatic mutations relevant to prostate cancer management, Labcorp #481220 might be more comprehensive.

  • Jeff Marchi – San Francisco

    sent: 6:57 PM

    Check out how running may stop prostate cancer from getting worse https://pmc.ncbi.nlm.nih.gov/articles/PMC12535562/

  • AnCan–John A

    sent: 6:57 PM

    All I can find so far on #483555 is it’s specially for prostate cancer

  • Eric James; Tyler TX

    sent: 7:05 PM

    has anyone had trouble with their camera working on Go To Meeting? Sometimes my camera works on these meetings and sometimes it doesn’t.

  • Jeff Marchi – San Francisco

    sent: 7:06 PM

    5 years, 4 different camers on PC, IPADs and iphone

  • Jeff Marchi – San Francisco

    sent: 7:06 PM

    never a problem

  • Jeff Marchi – San Francisco

    sent: 7:06 PM

    are you on a PC?

  • Eric James; Tyler TX

    sent: 7:06 PM

    yes

  • Jim Marshall, Veteran, Alexandria, VA

    sent: 7:07 PM

    When I cheaped out on buying Internet bandwidth. Jim

  • Jeff Marchi – San Francisco

    sent: 7:07 PM

    if camera doesn’t work go to gear at top right and check camera settings. is the right one selected

  • Eric James; Tyler TX

    sent: 7:08 PM

    I only have one camera. In the PC.

  • Eric James; Tyler TX

    sent: 7:08 PM

    I suppose I could try adding a new external camera

  • Gary Martin

    sent: 7:08 PM

    My PC camera did not work tonight for first time (after WIndows 11 update). Had to switch to external camera.

  • Jeff Marchi – San Francisco

    sent: 7:08 PM

    some windows 10 cameras don’t work with win 11

  • Mark N

    sent: 7:09 PM

    I had to restart my laptop to get it connect to my mic tonight

  • Eric James; Tyler TX

    sent: 7:09 PM

    I

  • Jeff Marchi – San Francisco

    sent: 7:09 PM

    restarting is a real fix many times

  • Jim Marshall, Veteran, Alexandria, VA

    sent: 7:09 PM

    When I do GOTO I make sure no other apps are running. Many folks leave a whole bunch of apps open which takes memory. Jim

  • Eric James; Tyler TX

    sent: 7:09 PM

    I’ve restarted, tried in Chrome and Outlook.

  • Jeff Marchi – San Francisco

    sent: 7:10 PM

    did the camera work with zoom or other app

  • Jim Marshall, Veteran, Alexandria, VA

    sent: 7:10 PM

    Are you using the Browser Interface for Chrome. Jim

  • Eric James; Tyler TX

    sent: 7:11 PM

    It has always worked in the past with zoom

  • Eric James; Tyler TX

    sent: 7:11 PM

    I’ve opened in Chrome and Outlook. I don’t know what an interface is.

  • Jeff Marchi – San Francisco

    sent: 7:11 PM

    ask goto support 877 582 7011

  • Jeff Marchi – San Francisco

    sent: 7:12 PM

    you mean edge not outlook

  • Eric James; Tyler TX

    sent: 7:12 PM

    yes

  • Eric James; Tyler TX

    sent: 7:13 PM

    I’ll try calling go to support and possibly try an external camera

  • Larry Schuller

    sent: 7:13 PM

    Interface: where two systems or programs talk to each other/exchange signals

  • Eric James; Tyler TX

    sent: 7:13 PM

    thanks

  • Jeff Marchi – San Francisco

    sent: 7:13 PM

    electrolytes give more energy

  • Larry Schuller

    sent: 7:14 PM

    Exercise begets Energy…Putit on your car’s sunvisor. Put it on your refrigerator. Put it on your mirror

  • Jeff Marchi – San Francisco

    sent: 7:15 PM

    Check out how running may stop prostate cancer from getting worse https://pmc.ncbi.nlm.nih.gov/articles/PMC12535562/

  • Jeff Marchi – San Francisco

    sent: 7:17 PM

    i could not run a mile on the track until I started taking electrolytes that enabled me to build up my stamina so I didn’t need it any longer

  • Jeff Marchi – San Francisco

    sent: 7:18 PM

    i run a mile twice every day

  • Jim Stewart Reno, NV

    sent: 7:24 PM

    have to sign off. grandkid duty…good night all!!!

  • Hank Zajic Springfield VA

    sent: 7:24 PM

    Thank you all for tonight’s session. I have to drop off.

  • RJ Smith (Seattle)

    sent: 7:25 PM

    Thanks all for the great words of encouragement! I’ll give myself a few breaks and still try to push through as far as is reasonable (without going too far).

  • Mark N

    sent: 7:28 PM

    Signing off, thanks !!

  • Larry Schuller

    sent: 7:28 PM

    Wait for it to come back? Or get ahead of what you think MIGHT happen? Hard choice.

  • Len

    sent: 7:43 PM

    Gary Martin and Mods – the PEACE-1 trial has a group of patients receiving RT added to the systemic triple therapy (ADT + Docetaxel + Abiraterone). The full results regarding the role of RT in this specific quadruplet combination are “highly anticipated.”

  • AnCan – rick

    sent: 7:53 PM

    https://ascopubs.org/doi/full/10.1200/JCO.22.02489

  • AnCan – rick

    sent: 7:53 PM

    https://www.medpagetoday.com/reading-room/asco/prostate-cancer/105340?xid=NL_ASCORR_2023-07-20&eun=g10110736d39r&pos=

  • Jim Marshall, Veteran, Alexandria, VA

    sent: 7:58 PM

    BE CONSISTENT getting the PSA test. Jim

  • Bob Y — Los Angeles

    sent: 8:01 PM

    Thank you, all. I am required by my family to leave the session. Appreciate all the help.

  • Jeff Marchi – San Francisco

    sent: 8:03 PM

    PSMA test was not available when my PSA rose after salvage radiation, if it was I would have held off Lupron

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 23, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 25, 2025

Hi-Risk/Recurrent/Advanced PrCa Video Chat, Nov 25, 2025

Happy Thanksgiving to all our AnCan particpants, especially if not on our mailing list. We’d have to ask why not, when you can sign up at https://ancan.org/contact-us/ and recive our great Newsletter/Reminder.

CORRECTION (rd)

I want to apologize and make a correction for someting I said in last Tuesday’s support group. At the end we were discussing adding a couple of Pluvicto treatments to Metastatic Directed Therapy. However this was for a man who had progressed rather than having just been diagnosed oligometastatic as in the LUNAR trial reported in the Reminder last week. I mentioned he might be eligible in the USA as Pluvicto is approved for metastatic hormone sensitive  prostate cancer. This is not the case, and I misspoke. PSMAddtion was positively reported for mHSPC use at the recent ESMO conference – thank you Dr. Paul for this link. To date, it has not been FDA approved. I knew of the trial and got ahead of the game; although I was confusing it with PSMAFore.

 

AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.

AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.

AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download

All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/

Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room

Editor’s Pick: Robust discussion around testoterone early on – and thoughts about combining therapies at the end.

Topics Discussed

how long to stay on HT leads to rich discussion on testosterone; did salvage cryo bring his PSA down? And he needs a GU MO QB; cupplementing T with Clomid is new to AnCan; casting around for intial treatment; ststarting Prolia that’s NO lifetime drug; tachycardia and AFib; recovering from 6x dicetaxel; b est treatment options for Stage T3 ; holding steady; allowing PSA to rise to find source of oligo-Mx; can we add Pluvicto to MDT later in the cycle?

Chat
  • Frank Ciambra sent: 5:10 PM

    my wife is a nurse working in cardiology ,im going to share this witth her

  • John M – Chicago sent: 5:11 PM

    Don I am doing great. Feeling stronger. Exercise is the KEY. Everything progressing according to plan. I’m going to my sons house to be with him, his wife and my grandson. What about you?

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:27 PM

    AFib – Join the club with others. Jim Marshall

  • Julian – Houston sent: 5:29 PM

    I had AFIB then had cardiac ablation in March 25 and then it went away!

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:30 PM

    AFib is Mutually exclusive with Vitamin K. Jim Marshall;

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:32 PM

    Have AFib and take Blood Thinner, Pradaxa, Metropolol Tartrate and a Statin – Pravastatin. Jim Marshall

  • AnCan – rick sent: 5:33 PM

    abir-A-terone

  • Jim Marshall, Veteran, Alexandria, VA sent: 5:34 PM

    Lupron/Eligard and Abi have warnings for those who have heart issues. Jim Marshall

  • Alfredo in Houston, TX sent: 5:37 PM

    Vitamin K potentially interferes with anticoagulants (blood thinners). And you also get vitamin K in your diet from leafy greens. Everyone please remember to discuss ALL supplements with your physician AND pharmacist.

  • TonyFig sent: 5:39 PM

    There is a strong link between sleep apnea bringing on A-Fib.

  • Alfredo in Houston, TX sent: 5:41 PM

    I am being called to supper now, so I must leave — but not before wishing a Happy Thanksgiving to everyone. Good night

  • AnCan–John A sent: 5:48 PM

    stereotactic body radiation therapy

  • Julian – Houston sent: 5:53 PM

    Happy Thanksgiving to all!!!

  • TonyFig sent: 5:56 PM

    Blood Thinner – a naturopath approach for anticoagulation can be quite risky as it may not present consistent and reliable levels to address A-Fib episodes or other cardiac issues. I discussed this with cardiac surgeons as well as a heart biologic replacement valve supplier. I would not take the risk of naturopath solution for this application.

    Nattokanese, Vit E, Ginger, Omega Oils in high dose, Cayene Pepper Tumeric, etc

  • John M – Chicago sent: 6:04 PM

    Have a great Thanksgiving everyone!

  • Dennis Correia sent: 6:07 PM

    Happy Thanksgiving all

  • Barry Blomquist sent: 6:07 PM

    Have to jump – Happy Thanksgiving to everyone and thank you all!

  • dan-s sent: 6:09 PM

    Thanks all – Happy Thanksgiving

  • Jerry Pelfrey sent: 6:10 PM

    Time to go. Everyone have a wonderful Thanksgiving.

  • Larry (Alaska) sent: 6:14 PM

    Suggesting Pluvicto as first-line treatment instead of ADT as first-line?

  • Bob Y — Los Angeles sent: 6:15 PM

    Thank you, all, for your good counsel.

  • David Muslin sent: 6:17 PM

    Gobble Gobble love you guys