Hi-Risk/Recurrent/Advanced PrCa Video Chat, Sep 23, 2025
UPCOMING PRESENTATION
Dr. JONATHAN EPSTEIN IS BACK for an AnCan webinar on Tue, Sep 30 at 8.pm Eastern!
“Interpreting Prostate Needle Biopsies in Today’s World”
Bx explained from early AS to advanced Pr Ca inc. AI – with lotsa time for Q&A.
Register at https://ow.ly/PpoX50WVsJ4
NEW monthy GAY & BISEXUAL MEN’S Prostate Cancer Group starting Tue, Oct 14.
Sign up at https://ancan.org/contact-us/
AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Hiding in plain sight, a new tumor docs failed to mention. (bn)
Topics Discussed
Upcoming AnCan group; newly diagnosed with a spot on his spine — consider zapping both prostate and tumor; what’s happening with Medicare and telehealth?; a Pluvicto update after his first treatment; after focal therapy, docs kept quiet about a new tumor, and it may now be escaping the prostate; lots of metastasis, PSA in the thousands, but he got doublet therapy, not triplet; a 0.04 PSA rise isn’t worrisome; he’s offered Clomid to raise testosterone (why not just take testosterone?); massive sweating spells that far exceed hot flashes; prior mastectomy complicates planned radiation for sore nipples; thanks to John Maxwell for giving AnCan the proceeds of his poetry collection during September; great experience from Dr. Guercio in Rochester; ready to shift his care to a top NYC hospital.
Chat Log
Ben Nathanson · 6:16 PM
NY Times: In Chicago, a New Approach to Gay and Bisexual Men With Prostate Cancer https://www.nytimes.com/2021/12/07/health/prostate-gay-sex-cancer.html?unlocked_article_code=1.oE8.Ij-J.lRa7OMYAXY5h&smid=url-share Allen Edel: Gay men should never have a prostatectomy https://www.prostatecancer.news/2021/
AnCan – rick · 6:29 PM
Kevin courtney is the GU med onc
AnCan – rick · 6:29 PM
at UTSW that I ws truying to recall.
Alfredo in Houston · 6:31 PM
https://profiles.utsouthwestern.edu/profile/131906/kevin-courtney.html
Alfredo in Houston · 6:32 PM
https://www.houstonmethodist.org/doctor/eleni-efstathiou/
AnCan – rick · 6:39 PM
PROMISE Trial https://www.prostatecancerpromise.org/?utm_campaign=ANCAN&utm_medium=link&utm_source=Webinar
Alfredo in Houston · 7:03 PM
https://www.uofmhealth.org/profile/2980/todd-matthew-morgan-md
AnCan – rick · 7:27 PM
Interpreting Prostate Needle Biopsies in Today’s World” with global expert Dr.Jonathan Epstein , Advanced Uropathology Register at https://ow.ly/PpoX50WVsJ4 – free.
Jim Marshall, Veteran, Alexandria, VA · 7:28 PM
https://ancan.us14.list-manage.com/track/click?u=ece3f3da90f82cb974b407396&id=9b15081950&e=7e455a27bb For Veterans Speaking Freely. Jim
Don Rogers · 8:08 PM
anastrozole 1 mg twice a week
AnCan – rick · 8:23 PM
casodex
Frank Ciambra · 8:35 PM
i just did my 7th pluvicto last wednesday i am recovering well and ave atrip planned to see my son and his family this weekend and will be jammig music tommorow night
Frank Ciambra · 8:38 PM
im going to see my son who recently retirrd from the teams in va beach mygrandsons have bb tornaments this weekend
AnCan – rick · 8:42 PM
Dr. McHugh, Dr. Rathkopf, Dr. Autio
AnCan – rick · 8:44 PM
geenitourinary (GU) medical oncologist
Hi-Risk/Recurrent/Advanced PCa Video Chat, Jan 28, 2025
Made a donation yet? If not, now’s the time – PLEASE! It’s AnCan’s Annual Fundraiser – once a year is the only time we ask for donations.
We’ve received less than 10% from participants, viewers and those receiving the Reminder combined. Time to step up and show appreciation and gratitude if you watch these videos, find them helpful., and want them to continue. Donate now at https://ancan.org/donate/
IF YOU’RE WATCHING THIS VIDEO, PLEASE COMPLETE OUR SHORT, 7-MINUTE ANCAN 2024 SURVEY... https://docs.google.com/forms/d/e/1FAIpQLSfw2B3rZTMWIPqTmzLYBl1CdN9qRJSpt0f72CoK6J00zllzWw/viewform AnCan needs your feedback and we also hope to take the results to medical conferences. We will be closing out in the next couple of weeks, so no more procrastinating please!! Analysis is scheduled to start soon and we are at 454 response in total. Let’s break 500!
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix & Blue Earth Diagnostic.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime!
Editor’s Pick: After 10 years (with a Gleason 10!) he’s ready for an ADT break. (bn)
Topics Discussed
Just three positive biopsy cores — but they’re in a bad place; five positive cores — but they’re all Gleason 3+3; he’s “an 81-year-old guy who’s been fighting cancer for 10 years” (with a Gleason 10!) and is thinking about a drug holiday; reminders from Rick: donations are still sadly low, and there’s still time to fill out the survey; re-irradiate old metastases that no longer show up in scans?; my docs don’t talk to each other — you’re calling that a team?; he’s never had a seizure till now — was it the Xtandi, and was it really a seizure?; should he fine-tune which statin he takes?; is prostate debulking useful for de novo men?; does he also need spot radiation in his bones if he’s also getting ADT?; those new bone pains might be caused by metastasis, not ADT; his urologist and the MSK nomogram are way apart on prognosis.
Chat Log
Len Sierra · 6:39 PM
https://www.mskcc.org/nomograms/prostate
AnCan – rick · 7:02 PM
PROMISE trial https://www.prostatecancerpromise.org/?utm_campaign=ANCAN&utm_medium=link&utm_source=Webinar
AnCan – rick · 7:29 PM
Survey …. https://docs.google.com/forms/d/e/1FAIpQLSfw2B3rZTMWIPqTmzLYBl1CdN9qRJSpt0f72CoK6J00zllzWw/viewform
AnCan – rick · 7:30 PM
Donations https://ancan.org/donate/
AnCan – rick · 8:06 PM
Study Doug is ref: https://pmc.ncbi.nlm.nih.gov/articles/PMC3255347/#abstract1
Dr. Jeff · 8:09 PM
According to current research, rosuvastatin appears to be more effective than simvastatin in potentially preventing or managing prostate cancer based on studies showing a stronger association with reduced cancer progression and mortality, with some evidence suggesting that rosuvastatin may have a more potent anti-tumor effect compared to simvastatin; however, more research is needed to fully understand the specific differences between the two drugs in relation to prostate cancer. Several studies have indicated that rosuvastatin may be associated with a greater reduction in prostate cancer mortality compared to simvastatin. So there are different conclusions.
AnCan – rick · 8:15 PM
Allen Edel https://pcnrv.blogspot.com/2018/09/no-survival-benefit-to-debulking.html
Larry Schuller · 8:30 PM
Firmagon and Orgovyx are receptor antagonists. Lupron is an agonist. They interrupt the instructions to the testes to make testosterone but agonists have two problems. The first is a testosterone surge (which has to be endured or suppressed) for about amonth and the second is that when you stop, it takes longer for your testosterone to recover
AnCan – rick · 9:03 PM
gdeliguori@imppllc.com
Jim Marshall, Alexandria, VA · 9:04 PM
Ming Zhou – Ming.zhou@mountsinai.org
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Janssen, Myriad Genetics, Novartis, Telix & Blue Earth Diagnostics.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime!
Editor’s Pick: He starts forgetting words in mid-sentence — is it his ADT? (bn)
Topics Discussed
Reminder to complete the AnCan survey — this includes those who watch our recordings!; entering “the most intense time of my 5 1/2 years with prostate cancer” as cancer recurs and chemo and bone radiation begin; 550 genes in his report — but not many will be actionable; close relatives have prostate cancer, but nothing shows on germline tests — perhaps it was a toxic exposure?; a colon cancer gene mutation is found to be driving his prostate cancer — does he have both?; bizarre insurance company denial has him scratching his head; don’t let VA paperwork stand in the way of a PSMA PET; platelet clumping in his blood tests isn’t likely to be disease-related; he starts forgetting words midsentence — is ADT to blame?; his doc restarts the ADT clock — this time with standard-of-care intensification; why CT and bone scan, but no PSMA PET?; doctors don’t talk to each other anymore, and patient care suffers.
Chat Log
Jim Marshall, Alexandria, VA · 6:36 PM
TCEs are known causes of Prostate. Cancer. Jim
AnCan – rick · 6:46 PM
MUTYH is the driver mutation that Joel had
AnCan – rick · 6:50 PM
Pesticides adn Prostate Cancer https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/cncr.35572?mc_cid=c1825f551a&mc_eid=838454d636
Jerry G, Brighton, MI · 7:19 PM
estradiol helps
Steve Roux, North Michigan · 7:24 PM
thanks! I’ll ask Dr. Fedak.
Steve L · 7:54 PM
Thanks to all. Happy Thanksgiving!
Steve L · 8:01 PM
Orca in photo was taken from my boat .
Julian – Houston · 8:08 PM
Happy Thanksgiving to ALL!!!
Steve Roux, North Michigan · 8:09 PM
This group empowers us to be our own best advocate.
J. Ward · 8:09 PM
Thankful for AnCan. Happy Thanksgiving, everyone!
Steve Roux, North Michigan · 8:10 PM
I need to sign off…..Tucker the rescue pup and my wife require my attention. HAVE AN AWESOME THANKSGIVING DAY!
Hi-Risk/Recurrent/Advanced PCa Video Chat, Oct 24, 2023
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Pfizer, Janssen, Myriad Genetics, Myovant, Telix & Blue Earth Diagnostics.
UPCOMING WEBINAR – Let’s talk Medicare 2024!Monday, Oct 30 8.00 pm Eastern Register at http://tinyurl.com/ancanmedicare . We plan NOT to make this scary!!!
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Editor’s pick: Facing the future as a three-year drug holiday falters. (bn)
Topics Discussed
Smooth recovery for kidney transplant patient who chose surgery over radiation; beginning of the end for a three-year drug holiday; turning to Pluvicto after chemo failure — which treatment is worse?; what it’s like undergoing Pluvicto therapy yet again; off ADT for 18 months, but now unexplained fatigue as PSA rises; controversy over Jonathan Epstein; prophylaxis for ADT bone loss; when triplet therapy makes sense; putting out the welcome mat for questions.
Chat Log
Peter Kafka – Maui · 7:20 PM
How much radiation from Pluvicto can a person safely have if multiple cycles are involved?
Al L · 7:26 PM
i didn’tmention it but I talk to Dr Scholz next week as well. He has patients that have had more Pluvicto sessions than I have had. I will be asking him about tolerating multiple rounds.
Peter Kafka – Maui · 7:33 PM
Has Marc had previous PSMA scans? Have they shown up stuff? Just wondering with low PSA profile.
Rick Davis · 7:45 PM
The Active Surveillor
Gary P · 7:52 PM
Here is the WP article:
Gary P · 7:54 PM
https://www.washingtonpost.com/health/2023/10/22/johns-hopkins-jonathan-epstein-pathology/
Hi-Risk/Recurrent/Advanced PCa Video Chat, Oct 10, 2023
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Foundation Medicine, Pfizer, Janssen, Myriad Genetics, Myovant, Telix & Blue Earth Diagnostics.
UPCOMING WEBINAR – Let’s talk Medicare 2024!Monday, Oct 30 8.00 pm Eastern Register at http://tinyurl.com/ancanmedicare . We plan NOT to make this scary!!!
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Editor’s pick:Does it make sense to keep your cancer off guard?… & the Group talks A-fib! (rd)
Topics Discussed
AnCan loses two long term men on same day; Zometa side effects; 3+3 (??) newbie addresses mets after 20 years; Gent running out of options needs current sequencing … and new doc; does it make sense to keep the cancer off guard?; addressing A-fib; reducing visceral fat with exercise addresses sarcopenia; darolutamide refused so Gent starts with Orgovyx alone; Payer wrongly refusing NGS somatic testing; blood in urine could be RT cystitis – cystoscopy required; PCa recurs only within the gland.
Chat Log
Matt Kriegersent · 3:32 PM
Here are my recent PSA trends, it’s been a bit of a rollercoaster and I would appreciate any feedback. My treatment history is external radiation and HDR brachytherapy completed April 2020, and I was on 2 anti-androgens until June 2022. So 9 (Sept.)/2022 <.06, 1/2023 .06, 3/2023 .06, 6/2023 .35, 7/2023 .17, 8/23 .24, 9/2023 .07 I’m seeing my urologist tomorrow because a few weeks ago, for the only time other than the one biopsy and brachy, I had some blood in my urine – that was surprising but hasn’t happened again since.
sent · 3:35 PM
Too many things to do. You need to talk with the group. You need to make changes now.
Jim Marshall, Alexandria, VAsent · 3:44 PM
Genitourinary Medical Oncologist
John Asent · 3:48 PM
“LHRH antagonist drugs include relugolix (Orgovyx) and degarelix (Firmagon). These will suppress testosterone rapidly and don’t need the premedication with another drug.
Jim Marshall, Alexandria, VAsent · 3:50 PM
Abiraterone for Castration-Sensitive guys is 5MG of Prednisone
John Asent · 3:50 PM
Then, a second dug may be added to add to the testosterone suppression: abiraterone or darolutamide or enzalutamide.
marc valenssent · 3:56 PM
genitourinary MedOnc at Fred Hutchinson in Seattle: Petros Grivas
J. Wardsent · 4:00 PM
I need to hop off now; thanks for allowing me speak about Ken Anderson.
