AnCan is grateful to the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics, and Foundation Medicine.
WELCOME all to our newly recorded Low/Intermediate Prostate Cancer Group. To receive notice when new recordings are posted, either follow us on this YouTube Channel or sign up to our Blog via https://ancan.org/contact-us/ – check New Blog box.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime!
Editor’s Pick: Focal therapy sounds great but has higher risk of recurrence. (bj)
Topics Discussed Importance of getting a second opinion on your biopsy slides by a specialist; don’t rush into a treatment without getting all the information; focal therapy sounds great but has higher risk of recurrence; active surveillance is a viable treatment option—it depends on your risk factors; cryotherapy vs HIFU—effectiveness vs side-effects; fears about erectile dysfunction (ED) and incontinence make focal therapy make it easy to jump on the focal therapy bandwagon; heart disease and hormone therapy (ADT) interactions; balancing open-heart surgery and managing prostate cancer (PCa); symptom management concerns cause me to lean toward IMRT (Intensity-Modulated Radiation Therapy) vs SBRT (Stereotactic Body Radiation Therapy); concerns about ADT side effects.
Chat
AnCan – Stuart sent a chat · 7:56 PM
Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881
AnCan – Stuart sent a chat · 7:56 PM
Dr. Jonathan Epstein – https://advanceduropathology.com/ Tel:516-760-2037 jepstein@imppllc.com
AnCan Bill sent a chat · 8:17 PM
If you are new, feel free to share your email address here and we will ensure you get our reminders.
AnCan Bill sent a chat · 8:32 PM
Steve, we were getting a lot of mic noise from you. We muted you.
Larry (Veteran, Alaskan) sent a chat · 8:33 PM
Do not overlook the potential value of getting a consult from a Medical Oncologist as opposed to Surgical or Radiological.
Martin Uthe sent a chat · 8:35 PM
Stuart, What is your email? Thank you.
Martin Uthe sent a chat · 8:36 PM
Larry, Thank you. M
AnCan – rick sent a chat · 8:36 PM
stuart@ancan.org
AnCan – rick sent a chat · 8:40 PM
I would disagrree with Larry at this time. With just a mm or two of 4+3 that we are checking with a 2nd opinion, most Genitourinary medical oncologists would not see you. You will not be able to get an appointment with Maha Hussein or David VanderWeele. Just seeing a general med onc will only confuse you.
Martin Uthe sent a chat · 8:41 PM
I am already confused!
Tom O NJ sent a chat · 8:44 PM
Martin confusion is why this group exist… keep coming keep doing research. I am new also and struggling w/ decision making.
Martin Uthe sent a chat · 8:45 PM
Thank you, Tom.
AnCan Bill sent a chat · 8:47 PM
Thanks Tom. We are here to help as best we can.
AnCan – Boykin sent a chat · 9:02 PM
Active Surveillance https://ancan.org/event/active-surveillance-prostate-cancer-2/2025-12-10/
Steve sent a chat · 9:10 PM
I was wondering if I should push for a Decipher test now?
Steve sent a chat · 9:11 PM
I tried to get one but its a bit hard from a foriegn country without a US Dr.
AnCan – rick sent a chat · 9:12 PM
Speak with Epstein first and also ask him. May help but I don’t know enough about Decipher. Dr. John does.
AnCan – rick sent a chat · 9:13 PM
We’re awae that it’s hard to get Decipher outside the country.
Steve sent a chat · 9:13 PM
ok 👍
Steve sent a chat · 9:13 PM
Yes I had Invitae genetic test … all negative.
Steve sent a chat · 9:14 PM
12 genes tested
AnCan – rick sent a chat · 9:14 PM
From Dr. John …. Steve: since there is some ambiguity, why not, if Epstein agrees
AnCan – rick sent a chat · 9:15 PM
Invitae is a germline test – very different to Decipher.
Steve sent a chat · 9:16 PM
Yep understand re: germline … I might have used wrong terminology
Steve sent a chat · 9:16 PM
Thanks Rick
Steve sent a chat · 9:17 PM
Any thoughts on state of the air radiation treatments if I end up there?
AnCan Bill sent a chat · 9:18 PM
bfranklin@ancan.org
Steve sent a chat · 9:19 PM
My connection dropped so not sure if I missed any texts
Steve sent a chat · 9:19 PM
re: Radiation.
AnCan – rick sent a chat · 9:20 PM
My bad…. didn’t realize the mic was on.
AnCan–John A sent a chat · 9:21 PM
Steve: likely SBRT
Steve sent a chat · 9:21 PM
ok, does that imply MRI Guided?
AnCan–John A sent a chat · 9:23 PM
Steve: probably at a state of the art center. Maybe CT
Steve sent a chat · 9:23 PM
CT?
AnCan–John A sent a chat · 9:23 PM
Computerized Axial Tomography
Steve sent a chat · 9:24 PM
Got ya, thanks 🙂
Steve sent a chat · 9:25 PM
SBRT with Real-Time Tracking (CyberKnife)?
AnCan–John A sent a chat · 9:26 PM
that’s an example yes
Steve sent a chat · 9:26 PM
MRI-Guided SBRT (MR-Linac: ViewRay MRIdian or Elekta Unity)
AnCan Bill sent a chat · 9:27 PM
Dr. Sanoj Punnen
Steve sent a chat · 9:27 PM
I will also check with my oncologist who I am seeing for Pet scan in a few hours
AnCan Bill sent a chat · 9:30 PM
https://sylvester-doctors.umiamihealth.org/
AnCan – rick sent a chat · 9:32 PM
https://sylvester-doctors.umiamihealth.org/
Steve sent a chat · 9:32 PM
I’m considering adding Dr. Kishan at UCLA to my trip.
Steve sent a chat · 9:36 PM
Did you have side effects?
Steve sent a chat · 9:37 PM
I like the idea he is on west coast as its already about 20-25 hrs flight time to get to CA 🙂
AnCan – rick sent a chat · 9:45 PM
dr.john@ancan.org
AnCan – rick sent a chat · 9:46 PM
https://www.uwmedicine.org/bios/effie-andrikopoulou
Steve sent a chat · 9:50 PM
Who was the Dr at UCSF who I should talk to re: Active Surveillance?
AnCan – rick sent a chat · 9:53 PM
UCSF – Peter Carrroll is the expert but winding down. Matt Cooperberg is one. If you can’t get to him, Sam Washington.
Steve sent a chat · 9:54 PM
Thanks Rick 👍
Steve sent a chat · 9:55 PM
Did you have the name and contact of the guy in Malaysia (I think it was you who mentioned him).
AnCan – rick sent a chat · 9:57 PM
Read this metastudy …. https://jamanetwork.com/journals/jamaoncology/article-abstract/2841671?guestAccessKey=d03b0908-90c8-497e-85cd-aebb43ec2a63&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jamaoncology&utm_content=olf-tfl_&utm_term=112025&mc_cid=0fa42784f6&mc_eid=838454d636
Steve sent a chat · 10:01 PM
Thanks so much for all the help guys. Makes my path alot more focused on best next steps. Much appreciated 🙏
Steve sent a chat · 10:05 PM
My connection dropped again… back on now
AnCan Bill sent a chat · 10:05 PM
We are glad you found us. Please keep coming to the group.
Steve sent a chat · 10:06 PM
You guys give us alot more confidence dealing with PC
Steve sent a chat · 10:10 PM
Rick/Stuart do you guys mind sharing your email?
AnCan Bill sent a chat · 10:11 PM
rd@ancan.org and stuart@ancan.org
AnCan – Stuart sent a chat · 10:11 PM
https://www.uclahealth.org/providers/amar-kishan
AnCan – Stuart sent a chat · 10:12 PM
MR-Linac
Paul N. sent a chat · 10:14 PM
Ask Keeshan about the Prostox test
Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 9, 2025
AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: Lotsa confusion throughout this week! To pick just one, Signatera MRD test.
Topics Discussed
Newbie has a great HCP team – but seeking more; Mayo bamboozles this Newbie – needs more and reliable information; another Newbie chose to leave himself on ADT for 5 years – and wonders about fatigue and weight gain he’s now shed w. GLP; muscle mass with low T; Regular finds Signatera MRD test – but it’s not yet FDA approved for prostate cancer… & Dr. Jack’s been following this test a long time; Epstein downgrades Gent from 4+5 to 4+3 – Kishan & MR Linac next; elevated liver enzymes after chemo; steady as he goes with 0.03 rise; what’s pituitary’s role for testosterone; PSA testing during Pluvicto
Chat
Alexander Lalov, Pendleton, IN
sent: 4:13 PM
Is the recording going to be made public?
Eric James; Tyler TX
sent: 4:13 PM
yes, on Youtube
AnCan – rick
sent: 4:14 PM
All our Recordings are posted on YuTube – over 700
Larry (Veteran, Alaskan)
sent: 4:16 PM
Check your camera shutter at the top of your screen
Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881
Jay – those are the 2 pathologists for a 2nd opinion.
Alexander Lalov, Pendleton, IN
sent: 5:27 PM
Bary, would you post the web address, please
Alexander Lalov, Pendleton, IN
sent: 5:28 PM
Oh, Withing is the name. Thnx!
John G.
sent: 5:28 PM
https://www.youtube.com/watch?v=Ado6dItMebE Yes, even on androgen deprivation therapy (ADT) with testosterone suppressed to near-zero (castration levels), you can increase muscle mass and strength through resistance training, though gains are typically modest and focused on counteracting atrophy rather than dramatic hypertrophy.[1][3] ## Evidence from Studies Multiple clinical trials show prostate cancer patients on ADT gaining muscle mass and fiber size after 12–20 weeks of supervised resistance training, including compound lifts like squats and presses, performed 2–3 times weekly. Progressive overload—gradually increasing weights—prevents fiber size decline in both type I and II muscles and boosts capillarization for better performance. These adaptations occur via mechanical loading and protein synthesis pathways independent of testosterone, such as IGF-1 signaling.
Larry (Veteran, Alaskan)
sent: 5:28 PM
YMCA “Livestrong” program is designed for cancer survivors. Look it up
Larry (Veteran, Alaskan)
sent: 5:29 PM
Government funded, so it is free and includes YMCA membership for the 12 week duration,
Active Surveillance Prostate Cancer Video Chat, December 10th, 2025
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, and Blue Earth Diagnostics.
Active Surveillance (AS) for low-risk prostate cancer involves unique challenges compared to other treatments. This online support group is designed for men and their caregivers who are currently on or considering AS. We hold four meetings monthly, recording only the second and fourth sessions. Our discussions cover a wide range of topics, including anxiety management, biopsy experiences, and the decision-making process around continuing or discontinuing AS. Newcomers are given priority to share their experiences, so we encourage you to join us.
You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/. Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/.
Chat Log:
Hugh -Houston
2nd Opinions for Biopsies: -Jonathan Epstein, MD https://advanceduropathology.com -Ming Zhou, MD, PHD Now at Mount Sinai Health System in New York City. If you have questions for him, please contact him directly at Email: Ming.zhou@mountsinai.org) -John Hopkins Pathology https://pathology.jhu.edu/patient-care/second-opinions
Derek
👍
Eric- Atlanta
PROMISE/COLOR Genetic Study w/ANCAN affiliate link: https://www.prostatecancerpromise.org/?utm_campaign=ANCAN&utm_medium=link&utm_source=Webinar
Eric- Atlanta
Men Speaking Freely: https://ancan.org/series/men-speaking-freely/
Eric- Atlanta
Food & Nutrition: https://ancan.org/wp-content/uploads/2020/11/Prostate-Ca-AS_Nov-2020.pdf
Eric- Atlanta
2nd Opinions for MRIs: Botimage AI for MRIs: https://botimageai.com/prostatid/ ~$250, can also be used for biopsy targeting guidance -Second opinion of MRI from Johns Hopkins Images and Reports for Providers | Johns Hopkins Radiology (hopkinsmedicine.org) Email: eradiologycenter@jhmi.edu Phone: 443-287-7378 Fax: 443-769-1210 NIH 2nd Opinion MRI (no fees): Choyke, Peter (NIH/NCI) Radiologist pchoyke@mail.nih.gov -Accolade Radiology NY, PA https://accoladeradiology.com/mritap.html Radiology Check (Switzerland) https://radiologycheck.com/en
AnCan Bill
Got to drop gentlemen. Thanks for helping out Martin (and everyone else). Take care.
Martin Uthe
thank you. Bill!
Eric- Atlanta
Thank you Bill
AnCan – rick
Great advice, Dan G
Martin Uthe
Hi guys- have to run. Thank you so much for your time and support. Talk to you on Friday, Howard.
Howard Wolinsky
Dr. Eggener UCLA
Howard Wolinsky
FYI on perineural invasion–sounds scary–https://howardwolinsky.substack.com/p/part-ii-the-perineural-invaders?utm_source=publication-search
Joel _ Manassas, VA
Much appreciate all the helpful discussion. Best to all
Must-Have Caregiver Tips to Get Organized, Find Help & Recharge by Cancer Support Community
“Cancer caregiving involves a wide range of experiences, feelings, and responsibilities. Whether you describe yourself as a caregiver, care partner, care supporter, or co-survivor, there’s no question that the role can be very rewarding and fulfilling. But caregiving can be hard physically and financially. Sometimes, it can also bring about complicated emotions like anger, shame, and guilt.”
First, know that you’re not alone. Many caregivers have the same questions, concerns, and challenges you may be experiencing. Click here for the full article from Cancer Support Community Gilda’s Club, where you will find helpful resources on navigating your care partnering journey.
Special Presentation: What if You Could Predict the Risk of Radiation Effects – Prostox and Beyond
Featuring Dr. Joanne Weidhaas, developer of the Prostox test. Dr. Weidhaas is a radiation oncologist/ professor at UCLA. Co-discoverer of the biomarker KRAS-variant, she co-founded MiraDx, maker of Prostox, and MiraKind to empower individuals with meaningful health information. Dr. Weidhass’ professional and academic resume includes MSKCC, Yale and Stanford, largely in breast cancer. She also finds time to care for 3 kids and save dogs!
AnCan Founder Rick Davis Discovers He Has VSS in Video Support Group
Here’s an interview with AnCan founder, Rick Davis. Watch Rick talk about the moment he realized he ALSO has visual snow syndrome – AFTER the group’s formation. In Rick’s own words, “It’s crazy how these things come together!”
Davis believes he has lived with Visual Snow Syndrome (VSS) since childhood, but learned to accommodate. His personal symptoms – seeing a “veil” of small dots, floaters, and light sensitivity – have given him deeper insight into the VSS support group. Davis strongly advocates for the medical community to formally recognize VSS and research a cure, while affirming AnCan’s role in providing a crucial, judgment-free virtual community where VSS sufferers realize they are not alone.
AnCan is grateful to the following sponsors for making this recording possible: Johnson and Johnson, Bayer, Novartis, Myriad Genetics, Telix, Blue Earth Diagnostics, and Foundation Medicine.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussion are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500, https://www.fda.gov/media/76299/download/.
All AnCan’s groups are free and drop-in … join us in person sometime!
Editor’s Pick: Pursuing VA disability and healthcare benefits simultaneously (bj)
Topics Discussed Veteran celebrates one year anniversary with AnCan by expressing his gratitude for all those who have helped him; pursuing VA disability and healthcare benefits simultaneously; travel reimbursement is happening and it is better to file earlier because the information is in the system; discussion about the Beneficiary Travel Self-Service System System (BTSSS); filing your own VA claims you need a computer, printer, and scanner—having a fax is optional; types of VA referrals community care versus private doctor; filling non-VA prescriptions at a VA pharmacy; Vet shares his experience in VA’s National Sports Progam.
Chat
AnCan – Boykin sent a chat · 8:12 PM
veterans@ancan.org
AnCan – Boykin sent a chat · 8:12 PM
you’re thinking about Richard
Eric Baker – Lafayette sent a chat · 8:14 PM
What is the VA’s definition of Incontinence?
Bob Schwartz U.S.N. Venice, FL. sent a chat · 8:18 PM
Thank you Col.
AnCan – Boykin sent a chat · 8:27 PM
They used Google Maps for me
AnCan – Boykin sent a chat · 8:29 PM
Beneficiary Travel Self-Service System (BTSSS)
TonyFig sent a chat · 8:38 PM
You can take photo or scan with cell phone
Larry Schuller sent a chat · 8:39 PM
Inkjet printer/scanner with the refillable internal ink tank. Lighter weight than lasers and ink costs MUCH less than ink cartridge types
Bruce Schrimpf sent a chat · 8:47 PM
Printing black and white on a color printer–i have had that happen!
AnCan – Boykin sent a chat · 8:50 PM
Fax is expensive at $2 to $3 a page; sometimes better to overnight mail
Larry Schuller sent a chat · 9:02 PM
What if the doctors disagree?
AnCan – Boykin sent a chat · 9:06 PM
Larry – If doctors disagree, then you need to ask why. In the end, the doctor has to agree with you.
AnCan – Boykin sent a chat · 9:06 PM
You’re right — you can’t make the doctors sign something they don’t believe
Bruce Schrimpf sent a chat · 9:10 PM
This might be unfair, but the object of the insurance company and perhaps the VA , is not to pay you. The object is to deny the claim!
Israel sent a chat · 9:12 PM
Go Navy! Beat Army this weekend!!
Israel sent a chat · 9:13 PM
What do you mean about being active in the VA?
Eric Baker – Lafayette sent a chat · 9:14 PM
I think that you mean, go Army beat Navy this weekend!! 🙂
Israel sent a chat · 9:15 PM
Ha, ha – nope. Go Navy!!⚓
Bruce Schrimpf sent a chat · 9:16 PM
Must run! Have a good Christmas all!
AnCan – Boykin sent a chat · 9:17 PM
Good night Bruce
Hank Zajic Springfield VA sent a chat · 9:20 PM
I have a very early start tomorrow so need to sign off. Thank you all for an excellent meeting tonight.
AnCan – Boykin sent a chat · 9:20 PM
Good night Hank
Mark WV sent a chat · 9:30 PM
sorry have to go good Nite
AnCan – Boykin sent a chat · 9:31 PM
Good night Mark
AnCan – Boykin sent a chat · 9:34 PM
veterans@ancan.org
AnCan – Boykin sent a chat · 9:36 PM
NCCN on December 9 at National Press Club
AnCan – rick sent a chat · 9:37 PM
https://www.cvent.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
Hi-Risk/Recurrent/Advanced PrCa Video Chat, Dec 1, 2025
AnCan thanks the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine.
Views expressed in this Recording are solely the opinion of AnCan Foundation, our Moderators and Participants.
AnCan does not accept sponsored promotion. Any drugs, protocols or devices discussed are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/
Join our other free and drop in groups:
Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/
Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/
Veterans Speaking freely… 4th Tuesday @ @ 8.00 pm Eastern Schmier Room
Editor’s Pick: How do you pick a doctor for a second opinion?
Topics Discussed
bladder control during salvage RT sessions; surgery vs RT for Gent with IDC-P; who to trust for a 2n opinion; gratitude for AnCan’s support; embarking on chemo on ice – report after 1st round;… abd finishing chemo – what next?: recurrence after salvage RT 7 yrs calls for PSMA – but KP is slow on the uptake; T level falls in hours after starrting Orgovyx… really??
Chat
AnCan – rick
sent: 6:03 PM
877 582 7011
AnCan – rick
sent: 6:05 PM
Number for GoTo technical support
Bob Y — Los Angeles
sent: 6:21 PM
Gerry, How did you decide on surgery as the first line of treatment?
Jeff Marchi – San Francisco
sent: 6:27 PM
wiesner clamp
AnCan–John A
sent: 6:40 PM
MSKCC nomogram
AnCan – rick
sent: 6:40 PM
http://nomograms.mskcc.org/Prostate/index.aspx
Gerry & Cynthia
sent: 6:41 PM
thank you
AnCan–John A
sent: 6:44 PM
I see PSA, gleason, age, NCCN risk, and tumor stage on the arterra report
AnCan–John A
sent: 6:45 PM
and the bx slides of course
AnCan – rick
sent: 6:51 PM
Partin tables
Mark N
sent: 6:52 PM
Labcorp test 481220
TonyFig
sent: 6:53 PM
here is another similar labcorp test https://www.labcorp.com/tests/483555/vistaseq-prostate-panel
AnCan–John A
sent: 6:56 PM
If your focus is on inherited genetic risk factors, the Color gene test is likely more complete. If you are seeking tumor-specific genetic profiling or somatic mutations relevant to prostate cancer management, Labcorp #481220 might be more comprehensive.
Jeff Marchi – San Francisco
sent: 6:57 PM
Check out how running may stop prostate cancer from getting worse https://pmc.ncbi.nlm.nih.gov/articles/PMC12535562/
AnCan–John A
sent: 6:57 PM
All I can find so far on #483555 is it’s specially for prostate cancer
Eric James; Tyler TX
sent: 7:05 PM
has anyone had trouble with their camera working on Go To Meeting? Sometimes my camera works on these meetings and sometimes it doesn’t.
Jeff Marchi – San Francisco
sent: 7:06 PM
5 years, 4 different camers on PC, IPADs and iphone
Jeff Marchi – San Francisco
sent: 7:06 PM
never a problem
Jeff Marchi – San Francisco
sent: 7:06 PM
are you on a PC?
Eric James; Tyler TX
sent: 7:06 PM
yes
Jim Marshall, Veteran, Alexandria, VA
sent: 7:07 PM
When I cheaped out on buying Internet bandwidth. Jim
Jeff Marchi – San Francisco
sent: 7:07 PM
if camera doesn’t work go to gear at top right and check camera settings. is the right one selected
Eric James; Tyler TX
sent: 7:08 PM
I only have one camera. In the PC.
Eric James; Tyler TX
sent: 7:08 PM
I suppose I could try adding a new external camera
Gary Martin
sent: 7:08 PM
My PC camera did not work tonight for first time (after WIndows 11 update). Had to switch to external camera.
Jeff Marchi – San Francisco
sent: 7:08 PM
some windows 10 cameras don’t work with win 11
Mark N
sent: 7:09 PM
I had to restart my laptop to get it connect to my mic tonight
Eric James; Tyler TX
sent: 7:09 PM
I
Jeff Marchi – San Francisco
sent: 7:09 PM
restarting is a real fix many times
Jim Marshall, Veteran, Alexandria, VA
sent: 7:09 PM
When I do GOTO I make sure no other apps are running. Many folks leave a whole bunch of apps open which takes memory. Jim
Eric James; Tyler TX
sent: 7:09 PM
I’ve restarted, tried in Chrome and Outlook.
Jeff Marchi – San Francisco
sent: 7:10 PM
did the camera work with zoom or other app
Jim Marshall, Veteran, Alexandria, VA
sent: 7:10 PM
Are you using the Browser Interface for Chrome. Jim
Eric James; Tyler TX
sent: 7:11 PM
It has always worked in the past with zoom
Eric James; Tyler TX
sent: 7:11 PM
I’ve opened in Chrome and Outlook. I don’t know what an interface is.
Jeff Marchi – San Francisco
sent: 7:11 PM
ask goto support 877 582 7011
Jeff Marchi – San Francisco
sent: 7:12 PM
you mean edge not outlook
Eric James; Tyler TX
sent: 7:12 PM
yes
Eric James; Tyler TX
sent: 7:13 PM
I’ll try calling go to support and possibly try an external camera
Larry Schuller
sent: 7:13 PM
Interface: where two systems or programs talk to each other/exchange signals
Eric James; Tyler TX
sent: 7:13 PM
thanks
Jeff Marchi – San Francisco
sent: 7:13 PM
electrolytes give more energy
Larry Schuller
sent: 7:14 PM
Exercise begets Energy…Putit on your car’s sunvisor. Put it on your refrigerator. Put it on your mirror
Jeff Marchi – San Francisco
sent: 7:15 PM
Check out how running may stop prostate cancer from getting worse https://pmc.ncbi.nlm.nih.gov/articles/PMC12535562/
Jeff Marchi – San Francisco
sent: 7:17 PM
i could not run a mile on the track until I started taking electrolytes that enabled me to build up my stamina so I didn’t need it any longer
Jeff Marchi – San Francisco
sent: 7:18 PM
i run a mile twice every day
Jim Stewart Reno, NV
sent: 7:24 PM
have to sign off. grandkid duty…good night all!!!
Hank Zajic Springfield VA
sent: 7:24 PM
Thank you all for tonight’s session. I have to drop off.
RJ Smith (Seattle)
sent: 7:25 PM
Thanks all for the great words of encouragement! I’ll give myself a few breaks and still try to push through as far as is reasonable (without going too far).
Mark N
sent: 7:28 PM
Signing off, thanks !!
Larry Schuller
sent: 7:28 PM
Wait for it to come back? Or get ahead of what you think MIGHT happen? Hard choice.
Len
sent: 7:43 PM
Gary Martin and Mods – the PEACE-1 trial has a group of patients receiving RT added to the systemic triple therapy (ADT + Docetaxel + Abiraterone). The full results regarding the role of RT in this specific quadruplet combination are “highly anticipated.”
Active Surveillance Prostate Cancer Video Chat, November 26th, 2025
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, and Blue Earth Diagnostics.
Active Surveillance (AS) for low-risk prostate cancer involves unique challenges compared to other treatments. This online support group is designed for men and their caregivers who are currently on or considering AS. We hold four meetings monthly, recording only the second and fourth sessions. Our discussions cover a wide range of topics, including anxiety management, biopsy experiences, and the decision-making process around continuing or discontinuing AS. Newcomers are given priority to share their experiences, so we encourage you to join us.
Chris L. (Windsor, CA)
Gut microbiome & phytochemical rich diet: YouTube: https://www.youtube.com/watch?v=0vR0QL3oR2k
Chris L. (Windsor, CA)
Asco highlights: https://www.urotoday.com/conference-highlights/asco-gu-2025/asco-gu-2025-prostate-cancer/158203-asco-gu-2025-gut-health-and-prostate-cancer-the-influence-of-a-specific-phytochemical-rich-food-capsule-plus-or-minus-a-probiotic-prebiotic-blend-on-symptoms-and-progression-a-randomised-double-blind-placebo-controlled-trial.html
Eric- Atlanta
https://howardwolinsky.substack.com/p/breaking-transperineal-biopsies-find?utm_source=publication-search
Bill Harris (Los Angeles)
Hi Rick. Hope all is well
Eric- Atlanta
Seminar link and info: https://aspatients.org/event/transperineal-vs-transrectal-biopsy-2025/
Eric- Atlanta
“Key Clinical Trials Driving the Debate Recent trials have brought new insights: Dr. Jim Hu (PREVENT, 2024): Zero infections with TP vs 1.4% with TR, suggesting a reduced risk of sepsis. Dr. Alastair Lamb and Dr. Richard Bryant (TRANSLATE, 2025): TP detected 5–6% more clinically significant cancers (Grade Group ≥ 2) and often required no antibiotics. Dr. Badar Mian (PRoBE-PC, 2024): Both methods proved safe and effective, giving patients more choice. Together, these studies have reshaped how experts think about prostate biopsy safety.”
Ray E Santa Monica Ca
https://www.perplexity.ai/search/262e8d77-95e5-4fef-aa07-9b7a313c25f1
Ray E Santa Monica Ca
Above is a run down on TP vs Transrectal biopsy
Bill (VA)
Walter Reed now performing TP
AnCan – rick
AnCan Prostate Cancer Debate Aug 2022 Dr. George vs Dr. Kaye https://ancan.org/webinar-prostate-cancer-biopsies-the-great-debate/
Bill Harris (Los Angeles)
Bill Harris wmharris@gmail.com
Bill Harris (Los Angeles)
(new inherited mutation group
Low/Intermediate PCa Video Chat, November 24, 2025
Low/Intermediate PCa Video Chat, November 24, 2025
AnCan is grateful to the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics, and Foundation Medicine.
WELCOME all to our newly recorded Low/Intermediate Prostate Cancer Group. To receive notice when new recordings are posted, either follow us on this YouTube Channel or sign up to our Blog via https://ancan.org/contact-us/ – check New Blog box.
AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence.
AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team.
AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download
AnCan’s Prostate Cancer Forum is back (https://ancan.org/forums). If you’d like to comment on anything you see in our Recordings or read in our Reminders, just sign up and go right ahead. You can also click on the Forum icon at the top right of the webpage.
All AnCan’s groups are free and drop-in … join us in person sometime!
Editor’s Pick: Manage “buyer’s remorse” by trusting the decision. (bj)
Topics Discussed Before treatment (cryotherapy/radiation), get a second pathology opinion (e.g., Dr. Epstein/Dr. Zhou) to confirm Gleason scores; high Decipher scores (e.g., 87) with favorable pathology (Gleason 3+4) may not necessitate leaving Active Surveillance; consult Centers of Excellence. Verify facility accreditation (NCI/NCCN “Centers of Excellence”); manage “buyer’s remorse” by trusting the decision (e.g., MRI-guided SBRT over surgery); weigh recurrence risks of focal versus whole-gland treatment; assess if a PSMA PET scan is necessary for localized intermediate-risk disease; review data on Androgen Deprivation Therapy (ADT) with radiation; consider short-term ADT (6 months) only for multiple intermediate risk factors; consider radiation (SBRT) with whole pelvic coverage over surgery for suspected extra-prostatic disease (lymph nodes) to avoid salvage radiation; use a low Decipher score (e.g., 0.26) to support foregoing ADT with radiation for intermediate-risk cancer.
Chat
AnCan – Stuart sent a chat · 7:58 PM
Dr. Ming Zhou Mount Sinai Health System Department of Pathology, Box 1194 Annenberg Bldg. 15th FL 1468 Madison Ave New York, NY 10029 Email: Ming.zhou@mountsinai.org Telephone: (212)241-8881
AnCan – Stuart sent a chat · 7:59 PM
Dr. Jonathan Epstein – https://advanceduropathology.com/ Tel:516-760-2037 jepstein@imppllc.com
AnCan–John A sent a chat · 8:41 PM
I am grateful to Howie for the term “sixes over sevens”. I am going to create a new Gleason system using poker terms.
AnCan Bill sent a chat · 8:42 PM
Well, I wouldn’t want a full house!
AnCan – rick sent a chat · 8:44 PM
McClure at Weill
AnCan – rick sent a chat · 8:46 PM
Vince Laudone and James Eastham at MSKCC
AnCan–John A sent a chat · 8:47 PM
Howie if you want I’ll read your complete Decipher report including GRID report
Mark Erickson sent a chat · 8:57 PM
can you please repeat how to tell if a group is a center of excellence
Larry (Alaska) sent a chat · 8:59 PM
There are 33 NCCN “Centers of Excellence” scattered across the country.
Larry (Alaska) sent a chat · 8:59 PM
https://www.nccn.org/home/member-institutions
AnCan–John A sent a chat · 8:59 PM
The accrediting groups are the NCCN National Comprehensive Cancer Network, or NCI National Cancer Institute. Go to the website and navigate to Centers of Excellence
AnCan–John A sent a chat · 9:00 PM
thx Larry
AnCan – rick sent a chat · 9:00 PM
877 582 7011
David in Portland, OR sent a chat · 9:01 PM
One picture=1,000 words. This map shows the location of all the NCCN member institutions: https://www.nccn.org/home/member-institutions/
AnCan – rick sent a chat · 9:02 PM
NCI Centers link http://www.cancer.gov/research/nci-role/cancer-centers/find
AnCan Bill sent a chat · 9:02 PM
Thank you Larry
Mark Erickson sent a chat · 9:02 PM
Thanks all
Larry (Alaska) sent a chat · 9:10 PM
I am a master or buyer’s remorse, seller’s remorse, second guessing and hindsight. But one makes a decision based on the best information you have and do not hesitate, dither or delay.
Ancan – Boykin sent a chat · 9:13 PM
Recognize that any treatment has consequences. Decide what you can live with. In the end, it’s a personal decision
Jim Stewart Reno, NV sent a chat · 9:22 PM
Have to sign off, Happy Thanksgiving everyone!!!!
Ancan – Boykin sent a chat · 9:23 PM
Happy Thanksgiving Jim!
AnCan Bill sent a chat · 9:23 PM
Take care Jim.
Bill (VA) sent a chat · 9:30 PM
First meeting I have understood what the focal/nano knife concern is on recurrence.
AnCan – rick sent a chat · 9:34 PM
Optimal Duration of Androgen Deprivation Therapy With Definitive Radiotherapy for Localized Prostate Cancer. https://ancan.us14.list-manage.com/track/click?u=ece3f3da90f82cb974b407396&id=06c8899f70&e=838454d636
AnCan – rick sent a chat · 9:35 PM
JAMA https://jamanetwork.com/journals/jamaoncology/fullarticle/2841671?guestAccessKey=d03b0908-90c8-497e-85cd-aebb43ec2a63&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jamaoncology&utm_content=olf-tfl_&utm_term=112025&mc_cid=0fa42784f6&mc_eid=838454d636
Mark Erickson sent a chat · 9:39 PM
Thanks everyone, Happy Thanksgiving
Ancan – Boykin sent a chat · 9:39 PM
Good Night Mark!
Larry (Alaska) sent a chat · 9:41 PM
Marc, it is a choice (in my mind) between 1) hit it hard and fast with risk of side effects or hit it minimally with s higher risk of recurrence
AnCan–John A sent a chat · 9:41 PM
‘night guys
David in Portland, OR sent a chat · 9:41 PM
Trip Trial compared six months to 30 months of ADT in randomized high risk patients who underwent beam plus brachy. It found no difference in outcomes. The incidence of biochemical recurrence rate at 7 years was 9%: https://www.redjournal.org/article/S0360-3016(23)07843-4/abstract
Bruce Schrimpf sent a chat · 9:56 PM
Great seeing and hearing from all of you! I plan on being with the high-risk group tomorrow. I will have an update tomorrow as I have recently returned from Mayo at Rochester.
Ancan – Boykin sent a chat · 9:57 PM
Good night Bruce!
AnCan – Stuart sent a chat · 10:05 PM
https://www.mskcc.org/nomograms/prostate
Tom O NJ sent a chat · 10:11 PM
Happy Thanksgiving All !!
